April 11 - April 17, 2022

A TCR Mimic CAR T Cell Specific for NDC80 Is Broadly Reactive With Solid Tumors and Hematological Malignancies.

Klatt MG, Dao T, Yang Z, Liu J, Mun SSoo, Dacek MM, Luo H, Gardner TJ, Bourne CM, Peraro L, et al. A TCR Mimic CAR T Cell Specific for NDC80 Is Broadly Reactive With Solid Tumors and Hematological Malignancies. Blood. 2022.

5--(-Boc-l-Alanine)-Renieramycin T Induces Cancer Stem Cell Apoptosis via Targeting Akt Signaling.

Suksamai D, Racha S, Sriratanasak N, Chaotham C, Aphicho K, Lin AChan Khine, Chansriniyom C, Suwanborirux K, Chamni S, Chanvorachote P. 5--(-Boc-l-Alanine)-Renieramycin T Induces Cancer Stem Cell Apoptosis via Targeting Akt Signaling. Mar Drugs. 2022;20(4).

Blockade of ALDH in Cisplatin-Resistant Ovarian Cancer Stem Cells In Vitro Synergistically Enhances Chemotherapy-Induced Cell Death.

Guo F, Yang Z, Sehouli J, Kaufmann AM. Blockade of ALDH in Cisplatin-Resistant Ovarian Cancer Stem Cells In Vitro Synergistically Enhances Chemotherapy-Induced Cell Death. Curr Oncol. 2022;29(4):2808-2822.

Nanocomposite of electrochemically reduced graphene oxide and gold nanourchins for electrochemical DNA detection.

Azimzadeh M, Aghili Z, Jannat B, Jafari S, Tafti SRafizadeh, Nasirizadeh N. Nanocomposite of electrochemically reduced graphene oxide and gold nanourchins for electrochemical DNA detection. IET Nanobiotechnol. 2022.

Single metal-organic framework-embedded nanopit arrays: A new way to control neural stem cell differentiation.

Cho Y-W, Jee S, Suhito IRosalina, Lee J-H, Park CGwon, Choi KMin, Kim T-H. Single metal-organic framework-embedded nanopit arrays: A new way to control neural stem cell differentiation. Sci Adv. 2022;8(16):eabj7736.

Escargot controls somatic stem cell maintenance through the attenuation of the insulin receptor pathway in Drosophila.

Demarco RSênos, Stack BJ, Tang AM, Voog J, Sandall SL, Southall TD, Brand AH, D Jones L. Escargot controls somatic stem cell maintenance through the attenuation of the insulin receptor pathway in Drosophila. Cell Rep. 2022;39(3):110679.

TGF-β signaling in myeloproliferative neoplasms contributes to myelofibrosis without disrupting the hematopoietic niche.

Yao J-C, Oetjen KA, Wang T, Xu H, Abou-Ezzi G, Krambs JR, Uttarwar S, Duncavage EJ, Link DC. TGF-β signaling in myeloproliferative neoplasms contributes to myelofibrosis without disrupting the hematopoietic niche. J Clin Invest. 2022.

Quantitative phosphoproteomics reveals ectopic ATP synthase on mesenchymal stem cells to promote tumor progression via ERK/c-Fos pathway activation.

Chang Y-W, Wang C-C, Yin C-F, Wu C-H, Huang H-C, Juan H-F. Quantitative phosphoproteomics reveals ectopic ATP synthase on mesenchymal stem cells to promote tumor progression via ERK/c-Fos pathway activation. Mol Cell Proteomics. 2022:100237.

Using Next Generation Sequencing to Identify Mutations Associated with Repair of a CAS9-induced Double Strand Break Near the CD4 Promoter.

Hu C, Doerksen T, Bugbee T, Wallace NA, Palinski R. Using Next Generation Sequencing to Identify Mutations Associated with Repair of a CAS9-induced Double Strand Break Near the CD4 Promoter. J Vis Exp. 2022;(181).

The beneficial effect of chronic muscular exercise on muscle fragility is increased by Prox1 gene transfer in dystrophic mdx muscle.

Monceau A, Delacroix C, Lemaitre M, Revet G, Furling D, Agbulut O, Klein A, Ferry A. The beneficial effect of chronic muscular exercise on muscle fragility is increased by Prox1 gene transfer in dystrophic mdx muscle. PLoS One. 2022;17(4):e0254274.

miR-150-3p enhances neuroprotective effects of neural stem cell exosomes after hypoxic-ischemic brain injury by targeting CASP2.

Luo H, Ye G, Liu Y, Huang D, Luo Q, Chen W, Qi Z. miR-150-3p enhances neuroprotective effects of neural stem cell exosomes after hypoxic-ischemic brain injury by targeting CASP2. Neurosci Lett. 2022:136635.

All-trans retinoic acid inhibits the osteogenesis of periodontal ligament stem cells by promoting IL-1β production via NF-κB signaling.

Guo L, Zhang Y, Liu H, Cheng Q, Yang S, Yang D. All-trans retinoic acid inhibits the osteogenesis of periodontal ligament stem cells by promoting IL-1β production via NF-κB signaling. Int Immunopharmacol. 2022;108:108757.