Papers of the Week

December 21 - December 27, 2020

Genetically-modified cell lines: categorisation and considerations for characterisation.

Ovchinnikov DA. Genetically-modified cell lines: categorisation and considerations for characterisation. Stem Cell Res. 2020;49:102103.

Metabolic regulation of prostate cancer heterogeneity and plasticity.

Peitzsch C, Gorodetska I, Klusa D, Shi Q, Alves TC, Pantel K, Dubrovska A. Metabolic regulation of prostate cancer heterogeneity and plasticity. Semin Cancer Biol. 2020.

Analysis of Tembusu virus infection of human cell lines and human induced pluripotent stem cell derived hepatocytes.

Ruangrung K, Chakritbudsabong W, Rungarunlert S, Smith DR, Hongeng S, Sirinonthanawech N, Boonarkart C, Pulmanausahakul R, Suptawiwat O, Auewarakul P. Analysis of Tembusu virus infection of human cell lines and human induced pluripotent stem cell derived hepatocytes. Virus Res. 2020:198252.

Gene Regulatory Network Analysis and Engineering Directs Development and Vascularization of Multilineage Human Liver Organoids.

Velazquez JJ, LeGraw R, Moghadam F, Tan Y, Kilbourne J, Maggiore JC, Hislop J, Liu S, Cats D, Lopes SMChuva de, et al. Gene Regulatory Network Analysis and Engineering Directs Development and Vascularization of Multilineage Human Liver Organoids. Cell Syst. 2020.

Single-Cell Sequencing of Developing Human Gut Reveals Transcriptional Links to Childhood Crohn's Disease.

Elmentaite R, Ross ADB, Roberts K, James KR, Ortmann D, Gomes T, Nayak K, Tuck L, Pritchard S, Bayraktar OAli, et al. Single-Cell Sequencing of Developing Human Gut Reveals Transcriptional Links to Childhood Crohn's Disease. Dev Cell. 2020.

Depletion of glioma stem cells by synergistic inhibition of mTOR and c-Myc with a biological camouflaged cascade brain-targeting nanosystem.

Ma Y, Zhang J, Rui Y, Rolle J, Xu T, Qian Z, Gu Y, Li S. Depletion of glioma stem cells by synergistic inhibition of mTOR and c-Myc with a biological camouflaged cascade brain-targeting nanosystem. Biomaterials. 2020;268:120564.

Chromatin and Nuclear Architecture in Stem Cells.

Meshorer E, Plath K. Chromatin and Nuclear Architecture in Stem Cells. Stem Cell Reports. 2020;15(6):1155-1157.

The Master Regulator Protein BAZ2B Can Reprogram Human Hematopoietic Lineage-Committed Progenitors into a Multipotent State.

Arumugam K, Shin W, Schiavone V, Vlahos L, Tu X, Carnevali D, Kesner J, Paull EO, Romo N, Subramaniam P, et al. The Master Regulator Protein BAZ2B Can Reprogram Human Hematopoietic Lineage-Committed Progenitors into a Multipotent State. Cell Rep. 2020;33(10):108474.

Epigenomic Reprogramming toward Mesenchymal-Epithelial Transition in Ovarian-Cancer-Associated Mesenchymal Stem Cells Drives Metastasis.

Fan H, Atiya HI, Wang Y, Pisanic TR, Wang T-H, Shih I-M, Foy KK, Frisbie L, Buckanovich RJ, Chomiak AA, et al. Epigenomic Reprogramming toward Mesenchymal-Epithelial Transition in Ovarian-Cancer-Associated Mesenchymal Stem Cells Drives Metastasis. Cell Rep. 2020;33(10):108473.

On Our Doorstep, A Precious Cargo From MSCs: The Role of Extracellular Vesicles in Stem Cell Therapy.

Cooke JP. On Our Doorstep, A Precious Cargo From MSCs: The Role of Extracellular Vesicles in Stem Cell Therapy. JACC Basic Transl Sci. 2020;5(11):1142-1144.

Long non-coding RNA Peg13 attenuates the sevoflurane toxicity against neural stem cells by sponging microRNA-128-3p to preserve Sox13 expression.

Jiang Y, Wang Y, Sun Y, Jiang H. Long non-coding RNA Peg13 attenuates the sevoflurane toxicity against neural stem cells by sponging microRNA-128-3p to preserve Sox13 expression. PLoS One. 2020;15(12):e0243644.

Quantitative comparison of the mRNA content of human iPSC-derived motor neurons and their extracellular vesicles.

Otake K, Adachi-Tominari K, Nagai H, Saito M, Sano O, Hirozane Y, Iwata H. Quantitative comparison of the mRNA content of human iPSC-derived motor neurons and their extracellular vesicles. FEBS Open Bio. 2020.

Leptin enhances adult neurogenesis and reduces pathological features in a transgenic mouse model of Alzheimer's disease.

Calió MLongoni, Mosini ACristina, Marinho DSouza, Salles GNogueira, Massinhani FHenrique, Ko GMi, Porcionatto MA. Leptin enhances adult neurogenesis and reduces pathological features in a transgenic mouse model of Alzheimer's disease. Neurobiol Dis. 2020:105219.

Hypoxic conditioned promotes the proliferation of human olfactory mucosa mesenchymal stem cells and relevant lncRNA and mRNA analysis.

He J, Huang Y, Liu J, Ge L, Tang X, Lu M, Hu Z. Hypoxic conditioned promotes the proliferation of human olfactory mucosa mesenchymal stem cells and relevant lncRNA and mRNA analysis. Life Sci. 2020:118861.