Papers of the Week

May 10 - May 16, 2021

Uremic endothelial-derived extracellular vesicles: mechanisms of formation and their role in cell adhesion, cell migration, inflammation, and oxidative stress.

Favretto G, da Cunha RStafim, Santos AFlores, Leitolis A, Schiefer EManfron, Gregório PCézar, Franco CRegina Cav, Massy Z, Dalboni MAparecida, Stinghen AEmilia Mar. Uremic endothelial-derived extracellular vesicles: mechanisms of formation and their role in cell adhesion, cell migration, inflammation, and oxidative stress. Toxicol Lett. 2021.

Early time-point cell morphology classifiers successfully predict human bone marrow stromal cell differentiation modulated by fiber density in nanofiber scaffolds.

Chen D, Dunkers JP, Losert W, Sarkar S. Early time-point cell morphology classifiers successfully predict human bone marrow stromal cell differentiation modulated by fiber density in nanofiber scaffolds. Biomaterials. 2021;274:120812.

Oligodendrocyte progenitor cell maturation is dependent on dual function of MCT8 in the transport of thyroid hormone across brain barriers and the plasma membrane.

Vatine GD, Shelest O, Barriga BK, Ofan R, Rabinski T, Mattis VB, Heuer H, Svendsen CN. Oligodendrocyte progenitor cell maturation is dependent on dual function of MCT8 in the transport of thyroid hormone across brain barriers and the plasma membrane. Glia. 2021.

Two Small Molecule Inhibitors Promote Reprogramming of Guangxi Bama Mini-Pig Mesenchymal Stem Cells Into Naive-Like State Induced Pluripotent Stem Cells.

Chen F, Shi D, Zou L, Yang X, Qiao S, Zhang R, Yang S, Deng Y. Two Small Molecule Inhibitors Promote Reprogramming of Guangxi Bama Mini-Pig Mesenchymal Stem Cells Into Naive-Like State Induced Pluripotent Stem Cells. Cell Reprogram. 2021.

microRNA-125b and its downstream Smurf1/KLF2/ATF2 axis as important promoters on neurological function recovery in rats with spinal cord injury.

Zhao K, Li R, Ruan Q, Meng C, Yin F, Zhu QS. microRNA-125b and its downstream Smurf1/KLF2/ATF2 axis as important promoters on neurological function recovery in rats with spinal cord injury. J Cell Mol Med. 2021.

Targeting microRNA-mediated gene repression limits adipogenic conversion of skeletal muscle mesenchymal stromal cells.

Wosczyna MN, Carbajal EEPerez, Wagner MW, Paredes S, Konishi CT, Liu L, Wang TT, Walsh RA, Gan Q, Morrissey CS, et al. Targeting microRNA-mediated gene repression limits adipogenic conversion of skeletal muscle mesenchymal stromal cells. Cell Stem Cell. 2021.

Current perspectives of limbal-derived stem cells and its application in ocular surface regeneration and limbal stem cell transplantation.

Singh V, Tiwari A, Kethiri AReddy, Sangwan VSingh. Current perspectives of limbal-derived stem cells and its application in ocular surface regeneration and limbal stem cell transplantation. Stem Cells Transl Med. 2021.

Comparison of Myeloablative Versus Reduced-Intensity Conditioning Regimens in Allogeneic Stem Cell Transplant Recipients with Acute Myelogenous Leukemia with MRD Negative Disease at the Time of Transplant: A Retrospective Cohort Study.

Yu J, Du Y, Ahmad S, Patel RD, Varela JCarlos, Chang C-C, Mori S. Comparison of Myeloablative Versus Reduced-Intensity Conditioning Regimens in Allogeneic Stem Cell Transplant Recipients with Acute Myelogenous Leukemia with MRD Negative Disease at the Time of Transplant: A Retrospective Cohort Study. Transplant Cell Ther. 2021.

Activation of HERV-K(HML-2) disrupts cortical patterning and neuronal differentiation by increasing NTRK3.

Nair VPadmanabha, Liu H, Ciceri G, Jungverdorben J, Frishman G, Tchieu J, Cederquist GY, Rothenaigner I, Schorpp K, Klepper L, et al. Activation of HERV-K(HML-2) disrupts cortical patterning and neuronal differentiation by increasing NTRK3. Cell Stem Cell. 2021.

Synthesis and biological evaluation of novel isoxazole-piperazine hybrids as potential anti-cancer agents with inhibitory effect on liver cancer stem cells.

İbiş K, Nalbat E, Çalışkan B, Kahraman DCansen, Cetin-Atalay R, Banoglu E. Synthesis and biological evaluation of novel isoxazole-piperazine hybrids as potential anti-cancer agents with inhibitory effect on liver cancer stem cells. Eur J Med Chem. 2021;221:113489.

Optimizing outcomes for haploidentical hematopoietic stem cell transplantation in severe aplastic anemia with intensive GVHD prophylaxis: a review of current findings.

Xu Z-L, Huang X-J. Optimizing outcomes for haploidentical hematopoietic stem cell transplantation in severe aplastic anemia with intensive GVHD prophylaxis: a review of current findings. Expert Rev Hematol. 2021.

Mesenchymal stem cell-derived exosomes containing miR-145-5p reduce inflammation in spinal cord injury by regulating the TLR4/NF-κB signaling pathway.

Jiang Z, Zhang J. Mesenchymal stem cell-derived exosomes containing miR-145-5p reduce inflammation in spinal cord injury by regulating the TLR4/NF-κB signaling pathway. Cell Cycle. 2021:1-17.

Stem cell restores thalamocortical plasticity to rescue cognitive deficit in neonatal intraventricular hemorrhage.

Ahn SYoon, Jie H, Jung W-B, Jeong J-H, Ko S, Im GHo, Park WSoon, Lee JHee, Chang YSil, Chung S. Stem cell restores thalamocortical plasticity to rescue cognitive deficit in neonatal intraventricular hemorrhage. Exp Neurol. 2021:113736.

Bone marrow-derived macrophages converted into cancer-associated fibroblast-like cells promote pancreatic cancer progression.

Iwamoto C, Ohuchida K, Shinkawa T, Okuda S, Otsubo Y, Okumura T, Sagara A, Koikawa K, Ando Y, Shindo K, et al. Bone marrow-derived macrophages converted into cancer-associated fibroblast-like cells promote pancreatic cancer progression. Cancer Lett. 2021.