Papers of the Week

October 11 - October 17, 2021

Plant Exosomes As Novel Nanoplatforms for MicroRNA Transfer Stimulate Neural Differentiation of Stem Cells In Vitro and In Vivo.

Xu X-H, Yuan T-J, Dad HAnwar, Shi M-Y, Huang Y-Y, Jiang Z-H, Peng L-H. Plant Exosomes As Novel Nanoplatforms for MicroRNA Transfer Stimulate Neural Differentiation of Stem Cells In Vitro and In Vivo. Nano Lett. 2021.

The interaction of Helicobacter pylori with cancer immunomodulatory stromal cells: new insight into gastric cancer pathogenesis.

Navashenaq JGholizadeh, Shabgah AGowhari, Banach M, Jamialahmadi T, Penson PE, Johnston TP, Sahebkar A. The interaction of Helicobacter pylori with cancer immunomodulatory stromal cells: new insight into gastric cancer pathogenesis. Semin Cancer Biol. 2021.

Exosomes derived from mesenchyml stem cells ameliorate oxygen-glucose deprivation/reoxygenation-induced neuronal injury via transferring MicroRNA-194 and targeting Bach1.

Li X, Zhang X, Liu Y, Pan R, Liang X, Huang L, Yang C. Exosomes derived from mesenchyml stem cells ameliorate oxygen-glucose deprivation/reoxygenation-induced neuronal injury via transferring MicroRNA-194 and targeting Bach1. Tissue Cell. 2021;73:101651.

Large-scale analysis of imprinting in naive human pluripotent stem cells reveals recurrent aberrations and a potential link to FGF signaling.

Keshet G, Benvenisty N. Large-scale analysis of imprinting in naive human pluripotent stem cells reveals recurrent aberrations and a potential link to FGF signaling. Stem Cell Reports. 2021.

Single-cell RNA-sequencing atlas of bovine caudal intervertebral discs: Discovery of heterogeneous cell populations with distinct roles in homeostasis.

Panebianco CJ, Dave A, Charytonowicz D, Sebra R, Iatridis JC. Single-cell RNA-sequencing atlas of bovine caudal intervertebral discs: Discovery of heterogeneous cell populations with distinct roles in homeostasis. FASEB J. 2021;35(11):e21919.

Reprogramming reactive glia into interneurons reduces chronic seizure activity in a mouse model of mesial temporal lobe epilepsy.

Lentini C, d'Orange M, Marichal N, Trottmann M-M, Vignoles R, Foucault L, Verrier C, Massera C, Raineteau O, Conzelmann K-K, et al. Reprogramming reactive glia into interneurons reduces chronic seizure activity in a mouse model of mesial temporal lobe epilepsy. Cell Stem Cell. 2021.

Optimal intervention time of ADSCs for hepatic ischemia-reperfusion combined with partial resection injury in rats.

Piao C, Zhang Q, Xu J, Wang Y, Liu T, Ma H, Liu G, Wang H. Optimal intervention time of ADSCs for hepatic ischemia-reperfusion combined with partial resection injury in rats. Life Sci. 2021:119986.

Slight up-regulation of Kir2.1 channel promotes endothelial progenitor cells to transdifferentiate into a pericyte phenotype by Akt/mTOR/Snail pathway.

Cui X, Li X, He Y, Yu J, Dong N, Zhao RChunhua. Slight up-regulation of Kir2.1 channel promotes endothelial progenitor cells to transdifferentiate into a pericyte phenotype by Akt/mTOR/Snail pathway. J Cell Mol Med. 2021.

FlowCT for the analysis of large immunophenotypic datasets and biomarker discovery in cancer immunology.

Botta C, Maia CDa Silva, Garcés J-J, Termini R, Perez C, Manrique I, Burgos L, Zabaleta A, Alignani D, Sarvide S, et al. FlowCT for the analysis of large immunophenotypic datasets and biomarker discovery in cancer immunology. Blood Adv. 2021.

Stem-Cell Based, Machine Learning Approach for Optimizing Natural Killer Cell-based Personalized Immunotherapy for High-Grade Ovarian Cancer.

Esmail S, Danter WR. Stem-Cell Based, Machine Learning Approach for Optimizing Natural Killer Cell-based Personalized Immunotherapy for High-Grade Ovarian Cancer. FEBS J. 2021.

SATB2 preserves colon stem cell identity and mediates ileum-colon conversion via enhancer remodeling.

Gu W, Wang H, Huang X, Kraiczy J, Singh PNP, Ng C, Dagdeviren S, Houghton S, Pellon-Cardenas O, Lan Y, et al. SATB2 preserves colon stem cell identity and mediates ileum-colon conversion via enhancer remodeling. Cell Stem Cell. 2021.

Stereospecific inhibition of AMPK by (R)-crizotinib induced changes to the morphology and properties of cancer and cancer stem cell-like cells.

Kim THyun, Park JHyeok, Park J, Son DMin, Baek J-Y, Jang HJun, Jung WKi, Byun Y, Kim SKyum, Park S-K. Stereospecific inhibition of AMPK by (R)-crizotinib induced changes to the morphology and properties of cancer and cancer stem cell-like cells. Eur J Pharmacol. 2021:174525.

Intravenous SPION-labeled adipocyte-derived stem cells targeted to the brain by magnetic attraction in a rat stroke model: An ultrastructural insight into cell fate within the brain.

García-Belda P, Prima-García H, Aliena-Valero A, Castelló-Ruiz M, Ulloa-Navas MJosé, Ten-Esteve A, Martí-Bonmatí L, Salom JB, García-Verdugo JManuel, Gil-Perotín S. Intravenous SPION-labeled adipocyte-derived stem cells targeted to the brain by magnetic attraction in a rat stroke model: An ultrastructural insight into cell fate within the brain. Nanomedicine. 2021:102464.

Metformin and sodium dichloroacetate effects on proliferation, apoptosis, and metabolic activity tested alone and in combination in a canine prostate and a bladder cancer cell line.

Klose K, Packeiser E-M, Müller P, Granados-Soler JLuis, Schille JTorben, Goericke-Pesch S, Kietzmann M, Escobar HMurua, Nolte I. Metformin and sodium dichloroacetate effects on proliferation, apoptosis, and metabolic activity tested alone and in combination in a canine prostate and a bladder cancer cell line. PLoS One. 2021;16(9):e0257403.

An enhancer-driven stem cell-like program mediated by SOX9 blocks intestinal differentiation in colorectal cancer.

Liang X, Duronio GN, Yang Y, Bala P, Hebbar P, Spisak S, Sahgal P, Singh H, Zhang Y, Xie Y, et al. An enhancer-driven stem cell-like program mediated by SOX9 blocks intestinal differentiation in colorectal cancer. Gastroenterology. 2021.

Damage Associated Molecular Patterns in Necrotic Femoral Head Inhibit Osteogenesis and Promote Fibrogenesis of Mesenchymal Stem Cells.

Deng Z, Ren Y, Park MSung, Kim HKW. Damage Associated Molecular Patterns in Necrotic Femoral Head Inhibit Osteogenesis and Promote Fibrogenesis of Mesenchymal Stem Cells. Bone. 2021:116215.

LEFTY-PITX2 signaling pathway is critical for generation of mature and ventricular cardiac organoids in human pluripotent stem cell-derived cardiac mesoderm cells.

Song M-H, Choi S-C, Noh J-M, Joo HJoon, Park C-Y, Cha J-J, Ahn THoon, Ko THee, Choi J-I, Na JEun, et al. LEFTY-PITX2 signaling pathway is critical for generation of mature and ventricular cardiac organoids in human pluripotent stem cell-derived cardiac mesoderm cells. Biomaterials. 2021;278:121133.