Papers of the Week

April 12 - April 18, 2021

Online monitoring of hiPSC expansion and hepatic differentiation in 3D culture by dielectric spectroscopy.

Isidro IA, Vicente P, Pais DAM, Almeida JI, Domingues M, Abecasis B, Zapata-Linares N, Rodriguez-Madoz JR, Prosper F, Aspegren A, et al. Online monitoring of hiPSC expansion and hepatic differentiation in 3D culture by dielectric spectroscopy. Biotechnol Bioeng. 2021.

In vivo survival and differentiation of Friedreich ataxia iPSC-derived sensory neurons transplanted in the adult dorsal root ganglia.

Viventi S, Frausin S, Howden SE, Lim SY, Finol-Urdaneta RK, McArthur JR, Abu-Bonsrah KDad, Ng W, Ivanusic J, Thompson L, et al. In vivo survival and differentiation of Friedreich ataxia iPSC-derived sensory neurons transplanted in the adult dorsal root ganglia. Stem Cells Transl Med. 2021.

Negative elongation factor regulates muscle progenitor expansion for efficient myofiber repair and stem cell pool repopulation.

Robinson DCL, Ritso M, Nelson GM, Mokhtari Z, Nakka K, Bandukwala H, Goldman SR, Park PJ, Mounier R, Chazaud B, et al. Negative elongation factor regulates muscle progenitor expansion for efficient myofiber repair and stem cell pool repopulation. Dev Cell. 2021.

H3K27ac bookmarking promotes rapid post-mitotic activation of the pluripotent stem cell program without impacting 3D chromatin reorganization.

Pelham-Webb B, Polyzos A, Wojenski L, Kloetgen A, Li J, Di Giammartino DCampigli, Sakellaropoulos T, Tsirigos A, Core L, Apostolou E. H3K27ac bookmarking promotes rapid post-mitotic activation of the pluripotent stem cell program without impacting 3D chromatin reorganization. Mol Cell. 2021.

Human pluripotent stem cells identify molecular targets of trisomy 12 in chronic lymphocytic leukemia patients.

Reid JC, Golubeva D, Boyd AL, Hollands CG, Henly C, Orlando L, Leber A, Hébert J, Morabito F, Cutrona G, et al. Human pluripotent stem cells identify molecular targets of trisomy 12 in chronic lymphocytic leukemia patients. Cell Rep. 2021;34(11):108845.

Heterospheroid formation improves therapeutic efficacy of mesenchymal stem cells in murine colitis through immunomodulation and epithelial regeneration.

Regmi S, Seo Y, Ahn J-S, Pathak S, Acharya S, Nguyen TTien, Yook S, Sung J-H, Park J-B, Kim JOh, et al. Heterospheroid formation improves therapeutic efficacy of mesenchymal stem cells in murine colitis through immunomodulation and epithelial regeneration. Biomaterials. 2021;271:120752.

Defibrotide In Hematopoietic Stem Cell Transplantation: A Multicenter Survey Study Of The Spanish Hematopoietic Stem Cell Transplantation Group (Geth).

Vicent MGonzalez, de Heredia CDíaz, de Pablo JGonzález, Molina B, Regueiro A, Pérez A, Palomo P, Corral LLópez, García E, Fernández JMaría, et al. Defibrotide In Hematopoietic Stem Cell Transplantation: A Multicenter Survey Study Of The Spanish Hematopoietic Stem Cell Transplantation Group (Geth). Eur J Haematol. 2021.

Culture Variabilities of Human iPSC-Derived Cerebral Organoids Are a Major Issue for the Modelling of Phenotypes Observed in Alzheimer's Disease.

Hernández D, Rooney LA, Daniszewski M, Gulluyan L, Liang HH, Cook AL, Hewitt AW, Pébay A. Culture Variabilities of Human iPSC-Derived Cerebral Organoids Are a Major Issue for the Modelling of Phenotypes Observed in Alzheimer's Disease. Stem Cell Rev Rep. 2021.

Is Adipose Tissue the Fountain of Youth? The Impact of Adipose Stem Cell Aging on Metabolic Homeostasis, Longevity, and Cell-Based Therapies.

Van Gijsen HSadie-. Is Adipose Tissue the Fountain of Youth? The Impact of Adipose Stem Cell Aging on Metabolic Homeostasis, Longevity, and Cell-Based Therapies. Adv Exp Med Biol. 2021;1286:225-250.

Tools and approaches for analysing the role of mitochondria in health, development and disease using human cerebral organoids.

Liput M, Magliaro C, Kuczyńska Z, Zayat V, Ahluwalia A, Buzanska L. Tools and approaches for analysing the role of mitochondria in health, development and disease using human cerebral organoids. Dev Neurobiol. 2021.

In Vitro Activation and Development of Goat Preantral Follicles Enclosed in Ovarian Tissue Co-cultured with Mesenchymal Stem Cells.

Sousa RP, Duarte ABeatriz G, Pinto Y, Sá NAR, Alves BG, Cibin FWS, Silva GC, Carvalho CES, Neto NMArgolo, Rodrigues APaula R, et al. In Vitro Activation and Development of Goat Preantral Follicles Enclosed in Ovarian Tissue Co-cultured with Mesenchymal Stem Cells. Reprod Sci. 2021.

Prediction Potency of Gonadal Hormone Alterations on Sexual Dysfunction After Hematopoietic Stem Cell Transplantation.

Xue C, Fang X, Sui X, Qu H, Wang N, Li Y, Liu X, Wang X, Wang X, Xu H, et al. Prediction Potency of Gonadal Hormone Alterations on Sexual Dysfunction After Hematopoietic Stem Cell Transplantation. Reprod Sci. 2021.

An assessment of bone marrow mesenchymal stem cell and human articular cartilage derived chondroprogenitor cocultures vs. monocultures.

Vinod E, Amirtham SManickam, Kachroo U. An assessment of bone marrow mesenchymal stem cell and human articular cartilage derived chondroprogenitor cocultures vs. monocultures. Knee. 2021;29:418-425.