Stembook Sections:
Cellular and nuclear reprogramming
Ectoderm specification and differentiation
Endoderm specification and differentiation
Epigenetics
Genomics and proteomics
Germ cell and somatic stem cell biology in reproduction
Manufacturing
Mesoderm specification and differentiation
Niche biology, homing, and migration
Renewal
Stem cell immunology
Therapeutic prospects
Tissue engineering
Cellular and nuclear reprogramming »
  • Inducing pluripotency
  • Stem cells in animal models of regeneration
  • Small RNAs – their biogenesis, regulation and function in embryonic stem cells
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Ectoderm specification and differentiation »
  • The cranial sensory nervous system: specification of sensory progenitors and placodes
  • Tooth organogenesis and regeneration
  • Melanocyte stem cells
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Endoderm specification and differentiation »
  • Pancreatic stem cells
  • Specification and patterning of the respiratory system
  • Liver development
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Epigenetics »
  • Epigenetic mechanisms controlling mesodermal specification
  • Imaging chromatin in embryonic stem cells
  • Epigenetic silencing during early lineage commitment
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Genomics and proteomics »
  • Proteomic studies of stem cells
  • Genome-wide transcription factor localization and function in stem cells
  • The pluripotent transcriptome
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Germ cell and somatic stem cell biology in reproduction »
  • Regulation of spermatogonia
  • piRNA function in germline development
  • The role of microRNAs in germline differentiation
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Manufacturing »
  • Regulatory challenges for the manufacture and scale-out of autologous cell therapies
  • From production to patient: challenges and approaches for delivering cell therapies
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Mesoderm specification and differentiation »
  • Epigenetic mechanisms controlling mesodermal specification
  • Mouse kidney development
  • Adult mesenchymal stem cells
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Niche biology, homing, and migration »
  • Hematopoietic stem cell trafficking
  • The neural stem cell microenvironment
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Renewal »
  • Aging and stem cell renewal
  • Quiescent stem cells in the niche
  • Mechanisms regulating stem cell polarity and the specification of asymmetric divisions
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Stem cell immunology »
  • Immunologic targeting of the cancer stem cell
  • Immunological considerations for cell therapy using human embryonic stem cell derivatives
  • Mouse models of graft-versus-host disease
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Therapeutic prospects »
  • The hematopoietic stem cell niche
  • Medical applications of epidermal stem cells
  • Mesenchymal stromal cells as a drug delivery system
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Tissue engineering »
  • Combining stem cells and biomaterial scaffolds for constructing tissues and cell delivery
  • Autologous approaches to tissue engineering
  • Flow perfusion culture of mesenchymal stem cells for bone tissue engineering
View all Chapters in Section »

News & Commentaries

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14 Feb 2019

Can We Repair the Brain? The Promise of Stem Cell Technologies for Treating Parkinson's Disease

JPD article news
Despite challenges, new advances in stem cell biology and genetic engineering show potential for better cell replacement therapies, say experts in a special supplement to JPD

Amsterdam, NL – Cell replacement may play an increasing role in alleviating the motor symptoms of Parkinson's disease in future. Writing in an open access special supplement the Journal of Parkinson's Disease, experts describe how newly developed stem cell technologies could be used to treat the disease and discuss the great promise, as well as the significant challenges, of stem cell treatment.

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10 Jan 2019

Salk Team Reveals Clues into Early Development of Autism Spectrum Disorder

salk news
Neurons from people with autism exhibit different patterns of growth and develop at a faster rate

La Jolla, CA, USA – Autism spectrum disorder (ASD) is a relatively common developmental disorder of communication and behavior that affects about 1 in 59 children in the US, according to the Centers for Disease Control and Prevention. Despite its prevalence, it is still unclear what causes the disease and what are the best ways to treat it.

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9 Jan 2019

Stem Cell Study Offers Clues for Optimizing Bone Marrow Transplants and More

usc news

Los Angeles, CA, USA – Bone marrow transplants, which involve transplanting healthy blood stem cells, offer the best treatment for many types of cancers, blood disorders and immune diseases. Even though 22,000 of these procedures are performed each year in the US, much remains to be understood about how they work.

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