March 18 - March 24, 2019

The DNA methylation profile of human spermatogonia at single-cell- and single-allele-resolution refutes its role in spermatogonial stem cell function and germ cell differentiation.

Fend-Guella DLucia, von Kopylow K, Spiess A-N, Schulze W, Salzbrunn A, Diederich S, Hajj NEl, Haaf T, Zechner U, Linke M. The DNA methylation profile of human spermatogonia at single-cell- and single-allele-resolution refutes its role in spermatogonial stem cell function and germ cell differentiation. Mol Hum Reprod. 2019.

SOX2-Dependent Transcription in Clock Neurons Promotes the Robustness of the Central Circadian Pacemaker.

Cheng AH, Bouchard-Cannon P, Hegazi S, Lowden C, Fung SW, Chiang C-K, Ness RW, Cheng H-YMary. SOX2-Dependent Transcription in Clock Neurons Promotes the Robustness of the Central Circadian Pacemaker. Cell Rep. 2019;26(12):3191-3202.e8.

In Vivo Generation of Post-infarct Human Cardiac Muscle by Laminin-Promoted Cardiovascular Progenitors.

Yap L, Wang J-W, Moreno-Moral A, Chong LYen, Sun Y, Harmston N, Wang X, Chong SYen, Öhman MK, Wei H, et al. In Vivo Generation of Post-infarct Human Cardiac Muscle by Laminin-Promoted Cardiovascular Progenitors. Cell Rep. 2019;26(12):3231-3245.e9.

Nidogen-1 Contributes to the Interaction Network Involved in Pro-B Cell Retention in the Peri-sinusoidal Hematopoietic Stem Cell Niche.

Balzano M, De Grandis M, Manh T-PVu, Chasson L, Bardin F, Farina A, Sergé A, Bidaut G, Charbord P, Hérault L, et al. Nidogen-1 Contributes to the Interaction Network Involved in Pro-B Cell Retention in the Peri-sinusoidal Hematopoietic Stem Cell Niche. Cell Rep. 2019;26(12):3257-3271.e8.

Amelioration of Huntington's disease phenotype in astrocytes derived from iPSC-derived neural progenitor cells of Huntington's disease monkeys.

Cho IKi, Yang B, Forest C, Qian L, Chan AWS. Amelioration of Huntington's disease phenotype in astrocytes derived from iPSC-derived neural progenitor cells of Huntington's disease monkeys. PLoS One. 2019;14(3):e0214156.

Cyclosporine A trough concentrations are associated with acute GvHD after non-myeloablative allogeneic hematopoietic cell transplantation.

de Kort EA, de Lil HS, Bremmers MEJ, van Groningen LFJ, Blijlevens NMA, Huls G, Brüggemann RJM, van Dorp S, van der Velden WJFM. Cyclosporine A trough concentrations are associated with acute GvHD after non-myeloablative allogeneic hematopoietic cell transplantation. PLoS One. 2019;14(3):e0213913.

Cytomegalovirus-specific CD8+ T-cells are associated with a reduced incidence of early relapse after allogeneic stem cell transplantation.

Varanasi PReddy, Ogonek J, Luther S, Dammann E, Stadler M, Ganser A, Borchers S, Hambach L, Weissinger EM. Cytomegalovirus-specific CD8+ T-cells are associated with a reduced incidence of early relapse after allogeneic stem cell transplantation. PLoS One. 2019;14(3):e0213739.

Regulation of miRNA biogenesis and histone modification by K63-polyubiquitinated DDX17 controls cancer stem-like features.

Kao S-H, Cheng W-C, Wang Y-T, Wu H-T, Yeh H-Y, Chen Y-J, Tsai M-H, Wu K-J. Regulation of miRNA biogenesis and histone modification by K63-polyubiquitinated DDX17 controls cancer stem-like features. Cancer Res. 2019.

The role of cellular interactions in the induction of hepatocyte polarity and functional maturation in stem cell-derived hepatic cells.

Blau BJ, Miki T. The role of cellular interactions in the induction of hepatocyte polarity and functional maturation in stem cell-derived hepatic cells. Differentiation. 2019;106:42-48.

Media composition modulates human embryonic stem cell morphology and may influence preferential lineage differentiation potential.

Harkness L, Chen X, Gillard M, Gray PPaul, Davies AMitchell. Media composition modulates human embryonic stem cell morphology and may influence preferential lineage differentiation potential. PLoS One. 2019;14(3):e0213678.

Advances of hyaluronic acid in stem cell therapy and tissue engineering, including current clinical trials.

López-Ruiz E, Jiménez G, L de Cienfuegos Á, Antic C, Sabata R, Marcha JA, Gálvez-Martín P. Advances of hyaluronic acid in stem cell therapy and tissue engineering, including current clinical trials. Eur Cell Mater. 2019;37:186-213.

Logic-Gated ROR1 Chimeric Antigen Receptor Expression Rescues T Cell-Mediated Toxicity to Normal Tissues and Enables Selective Tumor Targeting.

Srivastava S, Salter AI, Liggitt D, Yechan-Gunja S, Sarvothama M, Cooper K, Smythe KS, Dudakov JA, Pierce RH, Rader C, et al. Logic-Gated ROR1 Chimeric Antigen Receptor Expression Rescues T Cell-Mediated Toxicity to Normal Tissues and Enables Selective Tumor Targeting. Cancer Cell. 2019;35(3):489-503.e8.

Clearance of hematological malignancies by allogeneic cytokine-induced killer cell or donor lymphocyte infusions.

Merker M, Salzmann-Manrique E, Katzki V, Huenecke S, Bremm M, Bakhtiar S, Willasch A, Jarisch A, Soerensen J, Schulz A, et al. Clearance of hematological malignancies by allogeneic cytokine-induced killer cell or donor lymphocyte infusions. Biol Blood Marrow Transplant. 2019.

Mesenchymal stem cell exosomes enhance periodontal ligament cell functions and promote periodontal regeneration.

Chew JRen Jie, Chuah SJiunn, Teo KYe Wen, Zhang S, Lai RChai, Fu JHui, Lim LPeng, Lim SKiang, Toh WSeong. Mesenchymal stem cell exosomes enhance periodontal ligament cell functions and promote periodontal regeneration. Acta Biomater. 2019.