Biblio

Author Title Type [ Year(Asc)]
Filters: Author is Piersma, Aldert H  [Clear All Filters]
2022
de Leeuw VC, van Oostrom CTM, Wackers PFK, Pennings JLA, Hodemaekers HM, Piersma AH, Hessel EVS. Neuronal differentiation pathways and compound-induced developmental neurotoxicity in the human neural progenitor cell test (hNPT) revealed by RNA-seq. Chemosphere. 2022:135298.
2021
de Leeuw VC, Pennings JLA, Hessel EVS, Piersma AH. Exploring the biological domain of the neural embryonic stem cell test (ESTn): morphogenetic regulators, Hox genes and cell types, and their usefulness as biomarkers for embryotoxicity screening. Toxicology. 2021:152735.
Fragki S, Hoogenveen R, van Oostrom C, Schwillens P, Piersma AH, Zeilmaker MJ. Integrating in vitro chemical transplacental passage into a generic PBK model: A QIVIVE approach. Toxicology. 2021:153060.
2020
de Leeuw VC, van Oostrom CTM, Westerink RHS, Piersma AH, Heusinkveld HJ, Hessel EVS. An efficient neuron-astrocyte differentiation protocol from human embryonic stem cell-derived neural progenitors to assess chemical-induced developmental neurotoxicity. Reprod Toxicol. 2020.
Mennen RH, de Leeuw VC, Piersma AH. Oxygen tension influences embryonic stem cell maintenance and has lineage specific effects on neural and cardiac differentiation. Differentiation. 2020;115:1-10.
2015
Schulpen SHW, Theunissen PT, Pennings JLA, Piersma AH. Comparison of gene expression regulation in mouse- and human embryonic stem cell assays during neural differentiation and in response to valproic acid exposure. Reprod Toxicol. 2015.
Schulpen SHW, Pennings JLA, Piersma AH. Gene expression regulation and pathway analysis after valproic acid and carbamazepine exposure in a human embryonic stem cell based neuro-developmental toxicity assay. Toxicol Sci. 2015.
2014
van Dartel DAM, Schulpen SH, Theunissen PT, Bunschoten A, Piersma AH, Keijer J. Dynamic changes in energy metabolism upon embryonic stem cell differentiation support developmental toxicant identification. Toxicology. 2014;324C:76-87.