Biblio
Base editors: development and applications in biomedicine. Front Med. 2023.
. BCL11B and the NuRD complex cooperatively guard T-cell fate and inhibit OPA1-mediated mitochondrial fusion in T cells. EMBO J. 2023:e113448.
A booming field of large animal model research. Zool Res. 2024;45(2):311-313.
. Cas9-mediated replacement of expanded CAG repeats in a pig model of Huntington's disease. Nat Biomed Eng. 2023.
CRISPR Start-Loss: A Novel and Practical Alternative for Gene Silencing through Base-Editing-Induced Start Codon Mutations. Mol Ther Nucleic Acids. 2020;21:1062-1073.
. CRISPR/Cas9 mediated β-globin gene knockout in rabbits recapitulates human β-thalassemia. J Biol Chem. 2021:100464.
Development of a highly efficient prime editor system in mice and rabbits. Cell Mol Life Sci. 2023;80(11):346.
The disrupted balance between hair follicles and sebaceous glands in Hoxc13-ablated rabbits. FASEB J. 2018:fj201800928RR.
. DMP1 Ablation in the Rabbit Results in Mineralization Defects and Abnormalities in Haversian Canal/Osteon Microarchitecture. J Bone Miner Res. 2019.
. Efficient base editing for multiple genes and loci in pigs using base editors. Nat Commun. 2019;10(1):2852.
Efficient multi-nucleotide deletions using deaminase-Cas9 fusions in human cells. J Genet Genomics. 2022.
. Engineered domain-inlaid Nme2Cas9 adenine base editors with increased on-target DNA editing and targeting scope. BMC Biol. 2023;21(1):250.
Establishment of gene-edited pigs expressing human blood coagulation factor VII and albumin for bioartificial liver use. J Gastroenterol Hepatol. 2019.
. Expanded targeting scope and enhanced base editing efficiency in rabbit using optimized xCas9(3.7). Cell Mol Life Sci. 2019.
Generating functional cells through enhanced interspecies chimerism with human pluripotent stem cells. Stem Cell Reports. 2022.
Generation of a homozygous GRIN2A gene knockout human embryonic stem cell line using CRISPR/Cas9 system. Stem Cell Res. 2023;69:103121.
. Generation of knockout rabbits using transcription activator-like effector nucleases. Cell Regen (Lond). 2014;3(1):3.
Generation of multi-gene knockout rabbits using the Cas9/gRNA system. Cell Regen (Lond). 2014;3(1):12.
. Genome-edited rabbits: Unleashing the potential of a promising experimental animal model across diverse diseases. Zool Res. 2024;45(2):253-262.
. Highly Efficient Generation of GGTA1 Biallelic Knockout Inbred Mini-Pigs with TALENs. PLoS One. 2013;8(12):e84250.
Mini-PE, a prime editor with compact Cas9 and truncated reverse transcriptase. Mol Ther Nucleic Acids. 2023;33:890-897.
A new compact adenine base editor generated through deletion of HNH and REC2 domain of SpCas9. BMC Biol. 2023;21(1):155.
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