P450 oxidoreductase regulates barrier maturation by mediating retinoic acid metabolism in a model of the human BBB. Stem Cell Reports. 2022.
p53 inhibits Bmi-1-driven self-renewal and defines salivary gland cancer stemness. Clin Cancer Res. 2022..
p57 imposes the reserve stem cell state of gastric chief cells. Cell Stem Cell. 2022;29(5):826-839.e9.
p57Kip2 regulates embryonic blood stem cells by controlling sympathoadrenal progenitor expansion. Blood. 2022.
P63 targeted deletion under the FOXN1 promoter disrupts pre-and post-natal thymus development, function and maintenance as well as induces severe hair loss. PLoS One. 2022;17(1):e0261770.
PAI-1 is a vascular cell-specific HIF-2-dependent angiogenic factor that promotes retinal neovascularization in diabetic patients. Sci Adv. 2022;8(9):eabm1896.
Pan-cancer analysis of microRNA expression profiles highlights microRNAs enriched in normal body cells as effective suppressors of multiple tumor types: A study based on TCGA database. PLoS One. 2022;17(4):e0267291..
Pancreas agenesis mutations disrupt a lead enhancer controlling a developmental enhancer cluster. Dev Cell. 2022;57(16):1922-1936.e9..
Pancreatic islet transplantation in type 1 diabetes: 20-year experience from a single-centre cohort in Canada. Lancet Diabetes Endocrinol. 2022.
Pancreatic Stellate Cells Prolong Ex Vivo Islet Viability and Function and Improve Engraftment. Stem Cells Transl Med. 2022..
Paper of April Issue of Stem Cell Reviews and Reports Presents an Update on Acute Myeloid Leukemia Stem Cells: Origin, Characteristics, and Clinical Implications by Dr. David F. Claxton et al. Stem Cell Rev Rep. 2022..
Par3 regulates the asymmetric division of basal stem cells in psoriasis via the Par3/mInsc/LGN signaling axis. Cell Immunol. 2022;373:104496..
A parallelized, perfused 3D triculture model of leukemia for in vitro drug testing of chemotherapeutics. Biofabrication. 2022..
Parallels in signaling between development and regeneration in ectodermal organs. Curr Top Dev Biol. 2022;149:373-419..
A Parkinson's disease model composed of 3D bioprinted dopaminergic neurons within a biomimetic peptide scaffold. Biofabrication. 2022..
The Parkinson's disease protein alpha-synuclein is a modulator of processing bodies and mRNA stability. Cell. 2022;185(12):2035-2056.e33.
Partial epithelial-mesenchymal transition during enamel development. Clin Exp Dent Res. 2022..
Passive immunization against phosphorylated tau improves features of Huntington's disease pathology. Mol Ther. 2022..
Patch grafting of organoids of stem/progenitors into solid organs can correct genetic-based disease states. Biomaterials. 2022:121647.
Paternal eNOS deficiency in mice affects glucose homeostasis and liver glycogen in male offspring without inheritance of eNOS deficiency itself. Diabetologia. 2022.
The path from stem cells to red blood cells. Int J Hematol. 2022..
Pathogenesis of neural tube defects: The regulation and disruption of cellular processes underlying neural tube closure. WIREs Mech Dis. 2022:e1559..
Pathogenic mutation of TDP-43 impairs RNA processing in a cell type-specific manner: implications for the pathogenesis of ALS/FTLD. eNeuro. 2022..