Biblio

Author Title Type [ Year(Asc)]
Filters: Author is Scadden, David T  [Clear All Filters]
2024
Saha A, Palchaudhuri R, Lanieri L, Hyzy S, Riddle MJ, Panthera J, Eide C, Tolar J, Panoskaltsis-Mortari A, Gorfinkel L, et al. Alloengraftment without significant toxicity or GVHD in CD45 antibody-drug conjugate conditioned Fanconi anemia mice. Blood. 2024.
Maneix L, Iakova P, Lee CG, Moree SE, Lu X, Datar GK, Hill CT, Spooner E, King JCK, Sykes DB, et al. Cyclophilin A supports translation of intrinsically disordered proteins and affects haematopoietic stem cell ageing. Nat Cell Biol. 2024.
Mei S, Alchahin AM, Tsea I, Kfoury Y, Hirz T, Jeffries NElias, Zhao T, Xu Y, Zhang H, Sarkar H, et al. Single-cell analysis of immune and stroma cell remodeling in clear cell renal cell carcinoma primary tumors and bone metastatic lesions. Genome Med. 2024;16(1):1.
Kristiansen T, Mayerhofer C, Gustafsson K, Scadden DT. Stromal Cell Isolation from Hematopoietic Organs. J Vis Exp. 2024;(203).
2023
Kfoury YS, Ji F, Jain E, Mazzola MC, Schiroli G, Papazian A, Mercier FEmile, Sykes DBrian, Kiem A, Randolph MA, et al. The bone marrow stroma in human myelodysplastic syndrome reveals alterations that regulate disease progression. Blood Adv. 2023.
Gustafsson K, Rhee C, Frodermann V, Scadden EW, Li D, Iwamoto Y, Palchaudhuri R, Hyzy SL, Boitano AE, Nahrendorf M, et al. CD45-antibody-drug conjugate clears tissue resident myeloid cells from their niches enabling therapeutic adoptive cell transfer. bioRxiv. 2023.
Gustafsson K, Rhee C, Frodermann V, Scadden EW, Li D, Iwamoto Y, Palchaudhuri R, Hyzy S, Boitano A, Nahrendorf M, et al. Clearing and replacing tissue-resident myeloid cells with an anti-CD45-antibody-drug conjugate. Blood Adv. 2023.
Hirz T, Mei S, Sarkar H, Kfoury Y, Wu S, Verhoeven BM, Subtelny AO, Zlatev DV, Wszolek MW, Salari K, et al. Dissecting the immune suppressive human prostate tumor microenvironment via integrated single-cell and spatial transcriptomic analyses. Nat Commun. 2023;14(1):663.
Kooshesh KA, Foy BH, Sykes DB, Gustafsson K, Scadden DT. Health Consequences of Thymus Removal in Adults. N Engl J Med. 2023;389(5):406-417.
Rhee C, Scadden EW, Wong LPing, Schiroli G, Mazzola MC, Chea PL, Kato H, Hoyer FF, Mistry M, Lee B-K, et al. Limited plasticity of monocyte fate and function associated with epigenetic scripting at the level of progenitors. Blood. 2023.
2022
Haase C, Gustafsson K, Mei S, Yeh S-C, Richter D, Milosevic J, Turcotte R, Kharchenko PV, Sykes DB, Scadden DT, et al. Image-seq: spatially resolved single-cell sequencing guided by in situ and in vivo imaging. Nat Methods. 2022.
Mercier FEmile, Shi J, Sykes DBrian, Oki T, Jankovic M, Man CHim, Kfoury YSami, Miller E, He S, Zhu A, et al. In vivo genome-wide CRISPR screening in murine acute myeloid leukemia uncovers microenvironmental dependencies. Blood Adv. 2022.
Torres LS, Asada N, Weiss MJ, Trumpp A, Suda T, Scadden DT, Ito K. Recent advances in "sickle and niche" research - Tribute to Dr. Paul S Frenette. Stem Cell Reports. 2022;17(7):1509-1535.
2021
van Gastel N, Spinelli JB, Haigis MC, Scadden DT. Analysis of Leukemia Cell Metabolism through Stable Isotope Tracing in Mice. Bio Protoc. 2021;11(19):e4171.
M Blanco A, Sykes DB, Gu L, Wu M, Petroni R, Karnik R, Wawer M, Rico J, Li H, Jacobus WD, et al. Chromatin-state barriers enforce an irreversible mammalian cell fate decision. Cell Rep. 2021;37(6):109967.
Wang Y-P, Sharda A, Xu S-N, van Gastel N, Man CHim, Choi U, Leong WZhong, Li X, Scadden DT. Malic enzyme 2 connects the Krebs cycle intermediate fumarate to mitochondrial biogenesis. Cell Metab. 2021.
Kfoury YS, Ji F, Mazzola M, Sykes DB, Scherer AK, Anselmo A, Akiyama Y, Mercier F, Severe N, Kokkaliaris KD, et al. tiRNA signaling via stress-regulated vesicle transfer in the hematopoietic niche. Cell Stem Cell. 2021.
2020
Kokkaliaris KD, Scadden DT. Cell interactions in the bone marrow microenvironment affecting myeloid malignancies. Blood Adv. 2020;4(15):3795-3803.
Srikanthan MA, Humbert O, Haworth KG, Ironside C, Rajawat YS, Blazar BR, Palchaudhuri R, Boitano AE, Cooke MP, Scadden DT, et al. Effective Multi-lineage Engraftment in a Mouse Model of Fanconi Anemia Using Non-genotoxic Antibody-Based Conditioning. Mol Ther Methods Clin Dev. 2020;17:455-464.
Dai C, Li Q, May HI, Li C, Zhang G, Sharma G, A Sherry D, Malloy CR, Khemtong C, Zhang Y, et al. Lactate Dehydrogenase A Governs Cardiac Hypertrophic Growth in Response to Hemodynamic Stress. Cell Rep. 2020;32(9):108087.
Fang S, Chen S, Nurmi H, Leppänen V-M, Jeltsch M, Scadden DT, Silberstein L, Mikkola H, Alitalo K. VEGF-C Protects the Integrity of Bone Marrow Perivascular Niche. Blood. 2020.
2019
Ortinau LC, Wang H, Lei K, Deveza L, Jeong Y, Hara Y, Grafe I, Rosenfeld SB, Lee D, Lee B, et al. Identification of Functionally Distinct Mx1+αSMA+ Periosteal Skeletal Stem Cells. Cell Stem Cell. 2019;25(6):784-796.e5.
Scadden DT. Metcalf Lecture Award Manuscript-Applying niche biology to engineer T cell regenerative therapies. Exp Hematol. 2019.
Scadden DT. Stem Cell Transplant Approaches for Patients With Blood Cancers. Oncology (Williston Park). 2019;33(3).
Severe N, Karabacak NMurat, Gustafsson K, Baryawno N, Courties G, Kfoury Y, Kokkaliaris KD, Rhee C, Lee D, Scadden EW, et al. Stress-Induced Changes in Bone Marrow Stromal Cell Populations Revealed through Single-Cell Protein Expression Mapping. Cell Stem Cell. 2019.

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