Biblio

Author Title Type [ Year(Desc)]
Filters: Author is Wang, Timothy C  [Clear All Filters]
2014
Hayakawa Y, Jin G, Wang H, Chen X, Westphalen CB, Asfaha S, Renz BW, Ariyama H, Dubeykovskaya ZA, Takemoto Y, et al. CCK2R identifies and regulates gastric antral stem cell states and carcinogenesis. Gut. 2014.
2015
Worthley DL, Churchill M, Compton JT, Tailor Y, Rao M, Si Y, Levin D, Schwartz MG, Uygur A, Hayakawa Y, et al. Gremlin 1 Identifies a Skeletal Stem Cell with Bone, Cartilage, and Reticular Stromal Potential. Cell. 2015;160(1-2):269-284.
Asfaha S, Hayakawa Y, Muley A, Stokes S, Graham TA, Ericksen RE, Westphalen CB, von Burstin J, Mastracci TL, Worthley DL, et al. Krt19(+)/Lgr5(-) Cells Are Radioresistant Cancer-Initiating Stem Cells in the Colon and Intestine. Cell Stem Cell. 2015;16(6):627-638.
2016
C Westphalen B, Takemoto Y, Tanaka T, Macchini M, Jiang Z, Renz BW, Chen X, Ormanns S, Nagar K, Tailor Y, et al. Dclk1 Defines Quiescent Pancreatic Progenitors that Promote Injury-Induced Regeneration and Tumorigenesis. Cell Stem Cell. 2016;18(4):441-455.
2019
Münch NStephens, Fang H-Y, Ingermann J, H Maurer C, Anand A, Kellner V, Sahm V, Wiethaler M, Baumeister T, Wein F, et al. High-fat Diet Accelerates Carcinogenesis in a Mouse Model of Barrett's Esophagus via IL8 and Alterations to the Gut Microbiome. Gastroenterology. 2019.
2020
Fu N, Wu F, Jiang Z, Kim W, Ruan T, Malagola E, Ochiai Y, Nápoles OCompanioni, Valenti G, White RA, et al. Acute intestinal inflammation depletes/recruits histamine-expressing myeloid cells from the bone marrow leading to exhaustion of MB-HSCs. Cell Mol Gastroenterol Hepatol. 2020.
Demir IEkin, Reyes CMota, Alrawashdeh W, Ceyhan GO, Deborde S, Friess H, Görgülü K, Istvanffy R, Jungwirth D, Kuner R, et al. Clinically Actional Strategies for Studying Neural Influences in Cancer. Cancer Cell. 2020.
Karakasheva TA, Kijima T, Shimonosono M, Maekawa H, Sahu V, Gabre JT, Cruz-Acuña R, Giroux V, Sangwan V, Whelan KA, et al. Generation and Characterization of Patient-Derived Head and Neck, Oral, and Esophageal Cancer Organoids. Curr Protoc Stem Cell Biol. 2020;53(1):e109.
Hata M, Kinoshita H, Hayakawa Y, Konishi M, Tsuboi M, Oya Y, Kurokawa K, Hayata Y, Nakagawa H, Tateishi K, et al. GPR30-expressing Gastric Chief Cells do not Dedifferentiate but are Eliminated via PDK-dependent Cell Competition During Development of Metaplasia. Gastroenterology. 2020.
Chang W, Wang H, Kim W, Liu Y, Deng H, Liu H, Jiang Z, Niu Z, Sheng W, Nápoles OCompanioni, et al. Hormonal Suppression of Stem Cells Inhibits Symmetric Cell Division and Gastric Tumorigenesis. Cell Stem Cell. 2020.
Sheng W, Malagola E, Nienhüser H, Zhang Z, Kim W, Zamechek L, Sepulveda A, Hata M, Hayakawa Y, Zhao C-M, et al. Hypergastrinemia expands gastric ECL cells through CCK2R+ progenitor cells via ERK activation. Cell Mol Gastroenterol Hepatol. 2020.
Kunze B, Wein F, Fang H-Y, Anand A, Baumeister T, Strangmann J, Gerland S, Ingermann J, Münch NStephens, Wiethaler M, et al. Notch Signaling Mediates Differentiation in Barrett's Esophagus and Promotes Progression to Adenocarcinoma. Gastroenterology. 2020.
Middelhoff M, Nienhüser H, Valenti G, H Maurer C, Hayakawa Y, Takahashi R, Kim W, Jiang Z, Malagola E, Cuti K, et al. Prox1-positive cells monitor and sustain the murine intestinal epithelial cholinergic niche. Nat Commun. 2020;11(1):111.
Monje M, Borniger JC, D'Silva NJ, Deneen B, Dirks PB, Fattahi F, Frenette PS, Garzia L, Gutmann DH, Hanahan D, et al. Roadmap for the Emerging Field of Cancer Neuroscience. Cell. 2020;181(2):219-222.
2021
Das S, Feng Q, Balasubramanian I, Lin X, Liu H, Pellόn-Cardenas O, Yu S, Zhang X, Liu Y, Wei Z, et al. Colonic healing requires WNT produced by epithelium as well as Tagln+ and Acta2+ stromal cells. Development. 2021.
Hayakawa Y, Nakagawa H, Rustgi AK, Que J, Wang TC. Stem cells and origins of cancer in the upper gastrointestinal tract. Cell Stem Cell. 2021.
2022
Chen L, Lu H, Peng D, Cao LLong, Ballout F, Srirmajayam K, Chen Z, Bhat A, Wang TC, Capobianco A, et al. Activation of NOTCH signaling via DLL1 is mediated by APE1-redox-dependent NF-κB activation in oesophageal adenocarcinoma. Gut. 2022.
Malagola E, Hayakawa Y, Wang TC. R-spondin signaling in the stomach: isthmal Lgr4 rules. EMBO J. 2022:e111696.
2023
Lemmetyinen TT, Viitala EW, Wartiovaara L, Kaprio T, Hagström J, Haglund C, Katajisto P, Wang TC, Domènech-Moreno E, Ollila S. Fibroblast-derived EGF ligand Neuregulin-1 induces fetal-like reprogramming of the intestinal epithelium without supporting tumorigenic growth. Dis Model Mech. 2023.
Manieri E, Tie G, Malagola E, Seruggia D, Madha S, Maglieri A, Huang K, Fujiwara Y, Zhang K, Orkin SH, et al. Role of PDGFRA cells and a CD55 PDGFRA fraction in the gastric mesenchymal niche. Nat Commun. 2023;14(1):7978.
Chen Q, Weng K, Lin M, Jiang M, Fang Y, Chung SSW, Huang X, Zhong Q, Liu Z, Huang Z, et al. SOX9 modulates the transformation of gastric stem cells through biased symmetric cell division. Gastroenterology. 2023.
2024
Sun J, Sepulveda JL, Komissarova EV, Hills C, Seckar TD, LeFevre NM, Simonyan H, Young C, Su G, Del Portillo A, et al. CDKN2A-p16 deletion and activated KRAS drive Barrett's-like gland hyperplasia-metaplasia and synergize in the development of dysplasia pre-cancer lesions. Cell Mol Gastroenterol Hepatol. 2024.