Biblio

Author Title Type [ Year(Desc)]
Filters: Author is Clevers, Hans  [Clear All Filters]
2013
Petersen N, Reimann F, Bartfeld S, Farin HF, Ringnalda FC, Vries RGJ, van den Brink S, Clevers H, Gribble FM, de Koning EJP. Generation of L-cells in mouse and human small intestine organoids. Diabetes. 2013.
Sato T, Clevers H. Growing self-organizing mini-guts from a single intestinal stem cell: mechanism and applications. Science. 2013;340(6137):1190-4.
Lu J, Zhang S, Nakano H, Simmons DG, Wang S, Kong S, Wang Q, Shen L, Tu Z, Wang W, et al. A positive feedback loop involving gcm1 and fzd5 directs chorionic branching morphogenesis in the placenta. PLoS Biol. 2013;11(4):e1001536.
Peng WChuan, de Lau W, Madoori PK, Forneris F, Granneman JCM, Clevers H, Gros P. Structures of Wnt-Antagonist ZNRF3 and Its Complex with R-Spondin 1 and Implications for Signaling. PLoS One. 2013;8(12):e83110.
2014
Sun X, Terakawa J, Clevers H, Barker N, Daikoku T, Dey SK. Ovarian LGR5 is critical for successful pregnancy. FASEB J. 2014.
de Lau W, Peng WChuan, Gros P, Clevers H. The R-spondin/Lgr5/Rnf43 module: regulator of Wnt signal strength. Genes Dev. 2014;28(4):305-16.
2015
Dow LE, O'Rourke KP, Simon J, Tschaharganeh DF, van Es JH, Clevers H, Lowe SW. Apc Restoration Promotes Cellular Differentiation and Reestablishes Crypt Homeostasis in Colorectal Cancer. Cell. 2015;161(7):1539-1552.
Kundu P, Genander M, Strååt K, Classon J, Ridgway RA, Tan EHong, Björk J, Martling A, van Es J, Sansom OJ, et al. An EphB-Abl signaling pathway is associated with intestinal tumor initiation and growth. Sci Transl Med. 2015;7(281):281ra44.
Gregorieff A, Clevers H. In Situ Hybridization to Identify Gut Stem Cells. Curr Protoc Stem Cell Biol. 2015;34:2F.1.1-2F.1.11.
Drost J, van Jaarsveld RH, Ponsioen B, Zimberlin C, van Boxtel R, Buijs A, Sachs N, Overmeer RM, G Offerhaus J, Begthel H, et al. Sequential cancer mutations in cultured human intestinal stem cells. Nature. 2015.
Sato T, Clevers H. SnapShot: Growing Organoids from Stem Cells. Cell. 2015;161(7):1700-1700.e1.
2016
Broutier L, Andersson-Rolf A, Hindley CJ, Boj SF, Clevers H, Koo B-K, Huch M. Culture and establishment of self-renewing human and mouse adult liver and pancreas 3D organoids and their genetic manipulation. Nat Protoc. 2016;11(9):1724-1743.
Clevers H. Modeling Development and Disease with Organoids. Cell. 2016;165(7):1586-1597.
Kretzschmar K, Clevers H. Organoids: Modeling Development and the Stem Cell Niche in a Dish. Dev Cell. 2016;38(6):590-600.
Beumer J, Clevers H. Regulation and plasticity of intestinal stem cells during homeostasis and regeneration. Development. 2016;143(20):3639-3649.
Visvader JE, Clevers H. Tissue-specific designs of stem cell hierarchies. Nat Cell Biol. 2016.
Farin HF, Jordens I, Mosa MH, Basak O, Korving J, Tauriello DVF, de Punder K, Angers S, Peters PJ, Maurice MM, et al. Visualization of a short-range Wnt gradient in the intestinal stem-cell niche. Nature. 2016.
2018
Aden K, Bartsch K, Dahl J, Reijns MAM, Esser D, Sheibani-Tezerji R, Sinha A, Wottawa F, Ito G, Mishra N, et al. Epithelial RNase H2 Maintains Genome Integrity and Prevents Intestinal Tumorigenesis in Mice. Gastroenterology. 2018.
Fujii M, Clevers H, Sato T. Modeling Human Digestive Diseases with CRISPR-Cas9-modified Organoids. Gastroenterology. 2018.
Schmitt M, Schewe M, Sacchetti A, Feijtel D, van de Geer WS, Teeuwssen M, Sleddens HF, Joosten R, van Royen ME, van de Werken HJG, et al. Paneth Cells Respond to Inflammation and Contribute to Tissue Regeneration by Acquiring Stem-like Features through SCF/c-Kit Signaling. Cell Rep. 2018;24(9):2312-2328.e7.
Chan LHei, Zhou L, Ng KYu, Wong TLok, Lee TK, Sharma R, Loong JH, Ching YPang, Yuan Y-F, Xie D, et al. PRMT6 Regulates RAS/RAF Binding and MEK/ERK-Mediated Cancer Stemness Activities in Hepatocellular Carcinoma through CRAF Methylation. Cell Rep. 2018;25(3):690-701.e8.
Sasaki N, Clevers H. Studying cellular heterogeneity and drug sensitivity in colorectal cancer using organoid technology. Curr Opin Genet Dev. 2018;52:117-122.
2019
Post Y, Clevers H. Defining Adult Stem Cell Function at Its Simplest: The Ability to Replace Lost Cells through Mitosis. Cell Stem Cell. 2019;25(2):174-183.
Schneeberger K, Sánchez-Romero N, Ye S, van Steenbeek FG, Oosterhoff LA, Palacin IPla, Chen C, van Wolferen ME, van Tienderen G, Lieshout R, et al. Large-scale Production of LGR5-positive Bipotential Human Liver Stem Cells. Hepatology. 2019.
Joosten SPJ, Mizutani T, Spaargaren M, Clevers H, Pals ST. MET signaling overcomes EGFR inhibition in normal and colorectal cancer stem cells causing drug resistance. Gastroenterology. 2019.

Pages