Biblio
LIN28B promotes growth and tumorigenesis of the intestinal epithelium via Let-7. Genes Dev. 2013;27(20):2233-45.
. Culturing Adult Stem Cells from Mouse Small Intestinal Crypts. Cold Spring Harb Protoc. 2015;2015(4):pdb.prot078303.
. EGFR inhibitors prevent induction of cancer stem-like cells in esophageal squamous cell carcinoma by suppressing epithelial-mesenchymal transition. Cancer Biol Ther. 2015.
Gremlin 1 Identifies a Skeletal Stem Cell with Bone, Cartilage, and Reticular Stromal Potential. Cell. 2015;160(1-2):269-284.
Krt19(+)/Lgr5(-) Cells Are Radioresistant Cancer-Initiating Stem Cells in the Colon and Intestine. Cell Stem Cell. 2015;16(6):627-638.
Let-7 Represses Carcinogenesis and a Stem Cell Phenotype in the Intestine via Regulation of Hmga2. PLoS Genet. 2015;11(8):e1005408.
. . Dclk1 Defines Quiescent Pancreatic Progenitors that Promote Injury-Induced Regeneration and Tumorigenesis. Cell Stem Cell. 2016;18(4):441-455.
3D Human Esophageal Epithelium Steps Out from hPSCs. Cell Stem Cell. 2018;23(4):460-462.
. Generation and Characterization of Patient-Derived Head and Neck, Oral, and Esophageal Cancer Organoids. Curr Protoc Stem Cell Biol. 2020;53(1):e109.
Mesenchymal plasticity regulated by Prrx1 drives aggressive pancreatic cancer biology. Gastroenterology. 2020.
Stem cells and origins of cancer in the upper gastrointestinal tract. Cell Stem Cell. 2021.
. Engineered hydrogel reveals contribution of matrix mechanics to esophageal adenocarcinoma and identifies matrix-activated therapeutic targets. J Clin Invest. 2023.
The mitochondrial Ca channel MCU is critical for tumor growth by supporting cell cycle progression and proliferation. bioRxiv. 2023.
. SOX9 modulates the transformation of gastric stem cells through biased symmetric cell division. Gastroenterology. 2023.