Biblio

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Journal Article

Kim JJin, Lee SYun, Hwang Y, Kim S, Chung JMin, Park S, Yoon J, Yun H, Ji J-H, Chae S, et al. USP39 promotes non-homologous end-joining repair by poly(ADP-ribose)-induced liquid demixing. Nucleic Acids Res. 2021.

Seo BAm, Kim D, Hwang H, Kim MSeong, Ma S-X, Kwon S-H, Kweon SHo, Wang H, Yoo JMin, Choi S, et al. TRIP12 ubiquitination of glucocerebrosidase contributes to neurodegeneration in Parkinson's disease. Neuron. 2021.

Agarwal A, Park S, Ha S, Kwon J-S, Khan MRepon, Kang BGu, Dawson TM, Dawson VL, Andrabi SA, Kang S-U. Quantitative mass spectrometric analysis of the mouse cerebral cortex after ischemic stroke. PLoS One. 2020;15(4):e0231978.

M Hossain I, Lee JHee, Gagné J-P, Khan J, Poirier GG, King PH, Dawson VL, Dawson TM, Andrabi SA. Poly(ADP-ribose) mediates bioenergetic defects and redox imbalance in neurons following oxygen and glucose deprivation. FASEB J. 2024;38(6):e23556.

Stevens DA, Lee Y, Kang HChul, Lee BDae, Lee Y-I, Bower A, Jiang H, Kang S-U, Andrabi SA, Dawson VL, et al. Parkin loss leads to PARIS-dependent declines in mitochondrial mass and respiration. Proc Natl Acad Sci U S A. 2015.

Kang H, Park S, Jo A, Mao X, Kumar M, Park C-H, Ahn J-Y, Lee Y, Choi J-Y, Lee Y-S, et al. PARIS undergoes liquid-liquid phase separation and poly(ADP-ribose)-mediated solidification. EMBO Rep. 2023:e56166.

Park H, Kam T-I, Peng H, Chou S-C, Mehrabani-Tabari AA, Song J-J, Yin X, Karuppagounder SS, Umanah GK, Rao AVSubba, et al. PAAN/MIF nuclease inhibition prevents neurodegeneration in Parkinson's disease. Cell. 2022.

Panicker N, Kam T-I, Wang H, Neifert S, Chou S-C, Kumar M, Brahmachari S, Jhaldiyal A, Hinkle JT, Akkentli F, et al. Neuronal NLRP3 is a parkin substrate that drives neurodegeneration in Parkinson's disease. Neuron. 2022.

Chen Y-C, Umanah GKE, Dephoure N, Andrabi SA, Gygi SP, Dawson TM, Dawson VL, Rutter J. Msp1/ATAD1 maintains mitochondrial function by facilitating the degradation of mislocalized tail-anchored proteins. EMBO J. 2014.

Kam T-I, Hinkle JT, Dawson TM, Dawson VL. Microglia and astrocyte dysfunction in parkinson's disease. Neurobiol Dis. 2020:105028.

Wan Y-W, Al-Ouran R, Mangleburg CG, Perumal TM, Lee TV, Allison K, Swarup V, Funk CC, Gaiteri C, Allen M, et al. Meta-Analysis of the Alzheimer's Disease Human Brain Transcriptome and Functional Dissection in Mouse Models. Cell Rep. 2020;32(2):107908.

Choi S, Kim D, Kam T-I, Yun S, Kim S, Park H, Hwang H, Pletnikova O, Troncoso JC, Dawson VL, et al. Lysosomal Enzyme Glucocerebrosidase Protects against Aβ1-42 Oligomer-Induced Neurotoxicity. PLoS One. 2015;10(12):e0143854.

Eacker SM, Dawson TM, Dawson VL. The interplay of microRNA and neuronal activity in health and disease. Front Cell Neurosci. 2013;7:136.

Sterling JK, Kam T-I, Guttha S, Park H, Baumann B, Mehrabani-Tabari AA, Schultz H, Anderson B, Alnemri A, Chou S-C, et al. Interleukin-6 triggers toxic neuronal iron sequestration in response to pathological α-synuclein. Cell Rep. 2022;38(7):110358.

Krug S, Gupta M, Kumar P, Feller L, Ihms EA, Kang BGu, Srikrishna G, Dawson TM, Dawson VL, Bishai WR. Inhibition of host PARP1 contributes to the anti-inflammatory and antitubercular activity of pyrazinamide. Nat Commun. 2023;14(1):8161.

Lu W, Karuppagounder SS, Springer DA, Allen MD, Zheng L, Chao B, Zhang Y, Dawson VL, Dawson TM, Lenardo M. Genetic deficiency of the mitochondrial protein PGAM5 causes a Parkinson's-like movement disorder. Nat Commun. 2014;5:4930.

Bae J-H, Jo A, Cho SChun, Lee Y-I, Kam T-I, You C-L, Jeong H-J, Kim H, Jeong M-H, Jeong Y, et al. Farnesol prevents aging-related muscle weakness in mice through enhanced farnesylation of Parkin-interacting substrate. Sci Transl Med. 2023;15(711):eabh3489.

Xu J-C, Fan J, Wang X, Eacker SM, Kam T-I, Chen L, Yin X, Zhu J, Chi Z, Jiang H, et al. Cultured networks of excitatory projection neurons and inhibitory interneurons for studying human cortical neurotoxicity. Sci Transl Med. 2016;8(333):333ra48.

Karuppagounder SS, Wang H, Kelly T, Rush R, Nguyen R, Bisen S, Yamashita Y, Sloan N, Dang B, Sigmon A, et al. The c-Abl inhibitor IkT-148009 suppresses neurodegeneration in mouse models of heritable and sporadic Parkinson's disease. Sci Transl Med. 2023;15(679):eabp9352.

Umanah GKE, Ghasemi M, Yin X, Chang M, Kim JWan, Zhang J, Ma E, Scarffe LA, Lee Y-I, Chen R, et al. AMPA Receptor Surface Expression Is Regulated by S-Nitrosylation of Thorase and Transnitrosylation of NSF. Cell Rep. 2020;33(5):108329.

Scott L, Karuppagounder SS, Neifert S, Kang BGu, Wang H, Dawson VL, Dawson TM. The absence of Parkin does not promote dopamine or mitochondrial dysfunction in PolgA mitochondrial mutator mice. J Neurosci. 2022.

Hinkle JT, Dawson VL, Dawson TM. The A1 astrocyte paradigm: New avenues for pharmacological intervention in neurodegeneration. Mov Disord. 2019.