Biblio

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Journal Article

Hinkle JT, Dawson VL, Dawson TM. The A1 astrocyte paradigm: New avenues for pharmacological intervention in neurodegeneration. Mov Disord. 2019.

Scott L, Karuppagounder SS, Neifert S, Kang BGu, Wang H, Dawson VL, Dawson TM. The absence of Parkin does not promote dopamine or mitochondrial dysfunction in PolgA mitochondrial mutator mice. J Neurosci. 2022.

Umanah GKE, Ghasemi M, Yin X, Chang M, Kim JWan, Zhang J, Ma E, Scarffe LA, Lee Y-I, Chen R, et al. AMPA Receptor Surface Expression Is Regulated by S-Nitrosylation of Thorase and Transnitrosylation of NSF. Cell Rep. 2020;33(5):108329.

Karuppagounder SS, Wang H, Kelly T, Rush R, Nguyen R, Bisen S, Yamashita Y, Sloan N, Dang B, Sigmon A, et al. The c-Abl inhibitor IkT-148009 suppresses neurodegeneration in mouse models of heritable and sporadic Parkinson's disease. Sci Transl Med. 2023;15(679):eabp9352.

Xu J-C, Fan J, Wang X, Eacker SM, Kam T-I, Chen L, Yin X, Zhu J, Chi Z, Jiang H, et al. Cultured networks of excitatory projection neurons and inhibitory interneurons for studying human cortical neurotoxicity. Sci Transl Med. 2016;8(333):333ra48.

Bae J-H, Jo A, Cho SChun, Lee Y-I, Kam T-I, You C-L, Jeong H-J, Kim H, Jeong M-H, Jeong Y, et al. Farnesol prevents aging-related muscle weakness in mice through enhanced farnesylation of Parkin-interacting substrate. Sci Transl Med. 2023;15(711):eabh3489.

Lu W, Karuppagounder SS, Springer DA, Allen MD, Zheng L, Chao B, Zhang Y, Dawson VL, Dawson TM, Lenardo M. Genetic deficiency of the mitochondrial protein PGAM5 causes a Parkinson's-like movement disorder. Nat Commun. 2014;5:4930.

Krug S, Gupta M, Kumar P, Feller L, Ihms EA, Kang BGu, Srikrishna G, Dawson TM, Dawson VL, Bishai WR. Inhibition of host PARP1 contributes to the anti-inflammatory and antitubercular activity of pyrazinamide. Nat Commun. 2023;14(1):8161.

Sterling JK, Kam T-I, Guttha S, Park H, Baumann B, Mehrabani-Tabari AA, Schultz H, Anderson B, Alnemri A, Chou S-C, et al. Interleukin-6 triggers toxic neuronal iron sequestration in response to pathological α-synuclein. Cell Rep. 2022;38(7):110358.

Eacker SM, Dawson TM, Dawson VL. The interplay of microRNA and neuronal activity in health and disease. Front Cell Neurosci. 2013;7:136.

Choi S, Kim D, Kam T-I, Yun S, Kim S, Park H, Hwang H, Pletnikova O, Troncoso JC, Dawson VL, et al. Lysosomal Enzyme Glucocerebrosidase Protects against Aβ1-42 Oligomer-Induced Neurotoxicity. PLoS One. 2015;10(12):e0143854.

Wan Y-W, Al-Ouran R, Mangleburg CG, Perumal TM, Lee TV, Allison K, Swarup V, Funk CC, Gaiteri C, Allen M, et al. Meta-Analysis of the Alzheimer's Disease Human Brain Transcriptome and Functional Dissection in Mouse Models. Cell Rep. 2020;32(2):107908.

Kam T-I, Hinkle JT, Dawson TM, Dawson VL. Microglia and astrocyte dysfunction in parkinson's disease. Neurobiol Dis. 2020:105028.

Chen Y-C, Umanah GKE, Dephoure N, Andrabi SA, Gygi SP, Dawson TM, Dawson VL, Rutter J. Msp1/ATAD1 maintains mitochondrial function by facilitating the degradation of mislocalized tail-anchored proteins. EMBO J. 2014.

Panicker N, Kam T-I, Wang H, Neifert S, Chou S-C, Kumar M, Brahmachari S, Jhaldiyal A, Hinkle JT, Akkentli F, et al. Neuronal NLRP3 is a parkin substrate that drives neurodegeneration in Parkinson's disease. Neuron. 2022.

Park H, Kam T-I, Peng H, Chou S-C, Mehrabani-Tabari AA, Song J-J, Yin X, Karuppagounder SS, Umanah GK, Rao AVSubba, et al. PAAN/MIF nuclease inhibition prevents neurodegeneration in Parkinson's disease. Cell. 2022.

Kang H, Park S, Jo A, Mao X, Kumar M, Park C-H, Ahn J-Y, Lee Y, Choi J-Y, Lee Y-S, et al. PARIS undergoes liquid-liquid phase separation and poly(ADP-ribose)-mediated solidification. EMBO Rep. 2023:e56166.

Stevens DA, Lee Y, Kang HChul, Lee BDae, Lee Y-I, Bower A, Jiang H, Kang S-U, Andrabi SA, Dawson VL, et al. Parkin loss leads to PARIS-dependent declines in mitochondrial mass and respiration. Proc Natl Acad Sci U S A. 2015.

M Hossain I, Lee JHee, Gagné J-P, Khan J, Poirier GG, King PH, Dawson VL, Dawson TM, Andrabi SA. Poly(ADP-ribose) mediates bioenergetic defects and redox imbalance in neurons following oxygen and glucose deprivation. FASEB J. 2024;38(6):e23556.

Agarwal A, Park S, Ha S, Kwon J-S, Khan MRepon, Kang BGu, Dawson TM, Dawson VL, Andrabi SA, Kang S-U. Quantitative mass spectrometric analysis of the mouse cerebral cortex after ischemic stroke. PLoS One. 2020;15(4):e0231978.

Seo BAm, Kim D, Hwang H, Kim MSeong, Ma S-X, Kwon S-H, Kweon SHo, Wang H, Yoo JMin, Choi S, et al. TRIP12 ubiquitination of glucocerebrosidase contributes to neurodegeneration in Parkinson's disease. Neuron. 2021.

Kim JJin, Lee SYun, Hwang Y, Kim S, Chung JMin, Park S, Yoon J, Yun H, Ji J-H, Chae S, et al. USP39 promotes non-homologous end-joining repair by poly(ADP-ribose)-induced liquid demixing. Nucleic Acids Res. 2021.