Biblio

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Journal Article

Osipovich AB, Dudek KD, Trinh LT, Kim LH, Shrestha S, Cartailler J-P, Magnuson MA. ZFP92, a KRAB domain zinc finger protein enriched in pancreatic islets, binds to B1/Alu SINE transposable elements and regulates retroelements and genes. PLoS Genet. 2023;19(5):e1010729.

Trinh LT, Osipovich AB, Liu B, Shrestha S, Cartailler J-P, Wright CVE, Magnuson MA. Single-cell RNA sequencing of Sox17-expressing lineages reveals distinct gene regulatory networks and dynamic developmental trajectories. Stem Cells. 2023.

Nakhe AY, Dadi PK, Kim J, Dickerson MT, Behera S, Dobson JR, Shrestha S, Cartailler J-P, Sampson L, Magnuson MA, et al. The MODY-associated L114P mutation increases islet glucagon secretion and limits insulin secretion resulting in transient neonatal diabetes and glucose dyshomeostasis in adults. Elife. 2024;12.

Richardson TM, Saunders DC, Haliyur R, Shrestha S, Cartailler J-P, Reinert RB, Petronglo J, Bottino R, Aramandla R, Bradley AM, et al. Human pancreatic capillaries and nerve fibers persist in type 1 diabetes despite beta cell loss. Am J Physiol Endocrinol Metab. 2023.

Osipovich AB, Zhou FY, Chong JJ, Trinh LT, Cottam MA, Shrestha S, Cartailler J-P, Magnuson MA. Deletion of Ascl1 in pancreatic β-cells improves insulin secretion, promotes parasympathetic innervation, and attenuates dedifferentiation during metabolic stress. Mol Metab. 2023:101811.

Shrestha S, Saunders DC, Walker JT, Camunas-Soler J, Dai X-Q, Haliyur R, Aramandla R, Poffenberger G, Prasad N, Bottino R, et al. Combinatorial transcription factor profiles predict mature and functional human islet α and β cells. JCI Insight. 2021.

Shrestha S, Erikson G, Lyon J, Spigelman AF, Bautista A, Fox JEManning, Santos CDos, Shokhirev M, Cartailler J-P, Hetzer MW, et al. Aging compromises human islet beta cell function and identity by decreasing transcription factor activity and inducing ER stress. Sci Adv. 2022;8(40):eabo3932.