Biblio

Author Title [ Type(Desc)] Year
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Journal Article
Seibertz F, Rubio T, Springer R, Popp F, Ritter M, Liutkute A, Bartelt L, Stelzer L, Haghighi F, Pietras J, et al. Atrial fibrillation-associated electrical remodelling in human induced pluripotent stem cell-derived atrial cardiomyocytes: a novel pathway for antiarrhythmic therapy development. Cardiovasc Res. 2023.
Priesmeier L, Schoger E, Cyganek L, Zelarayán LCecilia. Combining a tetracycline (Tet)-inducible gRNA system and CRISPRa for titratable and timely controlled enhancement of endogenous SHISA3 activation in human induced pluripotent stem cells (hiPSC). Stem Cell Res. 2023;71:103163.
Khadjeh S, Hindmarsh V, Weber F, Cyganek L, Vidal RO, Torkieh S, Streckfuss-Bömeke K, Lbik D, Tiburcy M, Mohamed BA, et al. CRISPLD1: a novel conserved target in the transition to human heart failure. Basic Res Cardiol. 2020;115(3):27.
Li W, Stauske M, Luo X, Wagner S, Vollrath M, Mehnert CS, Schubert M, Cyganek L, Chen S, Hasheminasab S-M, et al. Disease Phenotypes and Mechanisms of iPSC-Derived Cardiomyocytes From Brugada Syndrome Patients With a Loss-of-Function SCN5A Mutation. Front Cell Dev Biol. 2020;8:592893.
Zhao Z, Li X, El-Battrawy I, Lan H, Zhong R, Xu Q, Huang M, Liao Z, Lang S, Zimmermann W-H, et al. Drug testing in human-induced pluripotent stem cell-derived cardiomyocytes from a patient with short QT syndrome type 1. Clin Pharmacol Ther. 2019.
Rössler U, Hennig AFloriane, Stelzer N, Bose S, Kopp J, Søe K, Cyganek L, Zifarelli G, Ali S, von der Hagen M, et al. Efficient generation of osteoclasts from human induced pluripotent stem cells and functional investigations of lethal CLCN7-related osteopetrosis. J Bone Miner Res. 2021.
Seibertz F, Sutanto H, Dülk R, Pronto JRyan D, Springer R, Rapedius M, Liutkute A, Ritter M, Jung P, Stelzer L, et al. Electrophysiological and calcium-handling development during long-term culture of human-induced pluripotent stem cell-derived cardiomyocytes. Basic Res Cardiol. 2023;118(1):14.
Schoger E, Zimmermann W-H, Cyganek L, Zelarayán LCecilia. Establishment of a second generation homozygous CRISPRa human induced pluripotent stem cell (hiPSC) line for enhanced levels of endogenous gene activation. Stem Cell Res. 2021;56:102518.
Schoger E, Zimmermann W-H, Cyganek L, Zelarayán LCecilia. Establishment of two homozygous CRISPR interference (CRISPRi) knock-in human induced pluripotent stem cell (hiPSC) lines for titratable endogenous gene repression. Stem Cell Res. 2021;55:102473.
Busley AViktoria, Kleinsorge M, Cyganek L. Generation of a genetically-modified induced pluripotent stem cell line harboring an oncogenic gene variant KRAS p.G12V. Stem Cell Res. 2023;69:103105.
Busley AViktoria, Cyganek L. Generation of a genetically-modified induced pluripotent stem cell line harboring a Noonan syndrome-associated gene variant MRAS p.G23V. Stem Cell Res. 2023;69:103108.
Schoger E, Argyriou L, Zimmermann W-H, Cyganek L, Zelarayán LCecilia. Generation of homozygous CRISPRa human induced pluripotent stem cell (hiPSC) lines for sustained endogenous gene activation. Stem Cell Res. 2020;48:101944.
Kruse V, Hamann C, Monecke S, Cyganek L, Elsner L, Hübscher D, Walter L, Streckfuss-Bömeke K, Guan K, Dressel R. Human Induced Pluripotent Stem Cells Are Targets for Allogeneic and Autologous Natural Killer (NK) Cells and Killing Is Partly Mediated by the Activating NK Receptor DNAM-1. PLoS One. 2015;10(5):e0125544.
El-Battrawy I, Besler J, Ansari U, Liebe V, Schimpf R, Tülümen E, Rudic B, Lang S, Odening K, Cyganek L, et al. Long-term follow-up of implantable cardioverter-defibrillators in Short QT syndrome. Clin Res Cardiol. 2019.
El-Battrawy I, Cyganek L, Zhou X, Akin I. 'Mature' resting membrane potentials in hiPSC-CMs: fact or artefact?-Authors' reply. Europace. 2019.
Dobner J, Nguyen T, Pavez-Giani MGustavo, Cyganek L, Distelmaier F, Krutmann J, Prigione A, Rossi A. mtDNA analysis using Mitopore. Mol Ther Methods Clin Dev. 2024;32(2):101231.
Rapöhn M, Cyganek L, Voigt N, Hasenfuß G, Lehnart SE, Wegener JW. Non-invasive analysis of contractility during identical maturations revealed two phenotypes in ventricular but not in atrial iPSC-CM. Am J Physiol Heart Circ Physiol. 2024.
Li Y, Dinkel H, Pakalniskyte D, Busley AViktoria, Cyganek L, Zhong R, Zhang F, Xu Q, Maywald L, Aweimer A, et al. Novel insights in the pathomechanism of Brugada syndrome and fever-related type 1 ECG changes in a preclinical study using human-induced pluripotent stem cell-derived cardiomyocytes. Clin Transl Med. 2023;13(3):e1130.
Knauer C, Haltern H, Schoger E, Kügler S, Roos L, Zelarayan LC, Hasenfuss G, Zimmermann W-H, Wollnik B, Cyganek L. Preclinical evaluation of CRISPR-based therapies for Noonan syndrome caused by deep-intronic variants. Mol Ther Nucleic Acids. 2024;35(1):102123.