Biblio
Atrial fibrillation-associated electrical remodelling in human induced pluripotent stem cell-derived atrial cardiomyocytes: a novel pathway for antiarrhythmic therapy development. Cardiovasc Res. 2023.
Combining a tetracycline (Tet)-inducible gRNA system and CRISPRa for titratable and timely controlled enhancement of endogenous SHISA3 activation in human induced pluripotent stem cells (hiPSC). Stem Cell Res. 2023;71:103163.
. CRISPLD1: a novel conserved target in the transition to human heart failure. Basic Res Cardiol. 2020;115(3):27.
Disease Phenotypes and Mechanisms of iPSC-Derived Cardiomyocytes From Brugada Syndrome Patients With a Loss-of-Function SCN5A Mutation. Front Cell Dev Biol. 2020;8:592893.
Drug testing in human-induced pluripotent stem cell-derived cardiomyocytes from a patient with short QT syndrome type 1. Clin Pharmacol Ther. 2019.
Efficient generation of osteoclasts from human induced pluripotent stem cells and functional investigations of lethal CLCN7-related osteopetrosis. J Bone Miner Res. 2021.
Electrophysiological and calcium-handling development during long-term culture of human-induced pluripotent stem cell-derived cardiomyocytes. Basic Res Cardiol. 2023;118(1):14.
Establishment of a second generation homozygous CRISPRa human induced pluripotent stem cell (hiPSC) line for enhanced levels of endogenous gene activation. Stem Cell Res. 2021;56:102518.
. Establishment of two homozygous CRISPR interference (CRISPRi) knock-in human induced pluripotent stem cell (hiPSC) lines for titratable endogenous gene repression. Stem Cell Res. 2021;55:102473.
. Generation of a genetically-modified induced pluripotent stem cell line harboring an oncogenic gene variant KRAS p.G12V. Stem Cell Res. 2023;69:103105.
. Generation of a genetically-modified induced pluripotent stem cell line harboring a Noonan syndrome-associated gene variant MRAS p.G23V. Stem Cell Res. 2023;69:103108.
. Generation of homozygous CRISPRa human induced pluripotent stem cell (hiPSC) lines for sustained endogenous gene activation. Stem Cell Res. 2020;48:101944.
. Human Induced Pluripotent Stem Cells Are Targets for Allogeneic and Autologous Natural Killer (NK) Cells and Killing Is Partly Mediated by the Activating NK Receptor DNAM-1. PLoS One. 2015;10(5):e0125544.
. Long-term follow-up of implantable cardioverter-defibrillators in Short QT syndrome. Clin Res Cardiol. 2019.
'Mature' resting membrane potentials in hiPSC-CMs: fact or artefact?-Authors' reply. Europace. 2019.
. mtDNA analysis using Mitopore. Mol Ther Methods Clin Dev. 2024;32(2):101231.
. Non-invasive analysis of contractility during identical maturations revealed two phenotypes in ventricular but not in atrial iPSC-CM. Am J Physiol Heart Circ Physiol. 2024.
. Novel insights in the pathomechanism of Brugada syndrome and fever-related type 1 ECG changes in a preclinical study using human-induced pluripotent stem cell-derived cardiomyocytes. Clin Transl Med. 2023;13(3):e1130.
Preclinical evaluation of CRISPR-based therapies for Noonan syndrome caused by deep-intronic variants. Mol Ther Nucleic Acids. 2024;35(1):102123.
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