Biblio

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Journal Article
Dreyer A-K, Hoffmann D, Lachmann N, Ackermann M, Steinemann D, Timm B, Siler U, Reichenbach J, Grez M, Moritz T, et al. TALEN-mediated functional correction of X-linked chronic granulomatous disease in patient-derived induced pluripotent stem cells. Biomaterials. 2015;69:191-200.
Ackermann M, Mucci A, McCabe A, Frei S, Wright K, Snapper SB, Lachmann N, Williams DA, Brendel C. Restored macrophage function ameliorates disease pathophysiology in a mouse model for IL10 receptor deficient very early onset inflammatory bowel disease. J Crohns Colitis. 2021.
Brinkert K, Hedtfeld S, Burhop A, Gastmeier R, Gad P, Wedekind D, Kloth C, Rothschuh J, Lachmann N, Hetzel M, et al. Rescue from Pseudomonas aeruginosa airway infection via stem cell transplantation. Mol Ther. 2020.
Gonzalez CRodriguez, Schevel H, Hansen G, Schwerk N, Lachmann N. Pulmonary Alveolar Proteinosis and new therapeutic concepts. Klin Padiatr. 2024.
Haake K, Lachmann N. New Drugs for an Old Foe: Mycobacterium tuberculosis Meets PSC-Derived Macrophages. Stem Cell Reports. 2019;13(6):957-959.
Dannenmann B, Klimiankou M, Oswald B, Solovyeva A, Mardan J, Nasri M, Ritter M, Zahabi A, Arreba-Tutusaus P, Mir P, et al. iPSC modeling of stage-specific leukemogenesis reveals BAALC as a key oncogene in severe congenital neutropenia. Cell Stem Cell. 2021.
Haake K, Wüstefeld T, Merkert S, Lüttge D, Göhring G, Auber B, Baumann U, Lachmann N. Human STAT1 gain-of-function iPSC line from a patient suffering from chronic mucocutaneous candidiasis. Stem Cell Res. 2020;43:101713.
Hashtchin ARafiei, Fehlhaber B, Hetzel M, Manstein F, Stalp JLennart, Glage S, Abeln M, Zweigerdt R, Munder A, Viemann D, et al. Human iPSC-derived macrophages for efficient Staphylococcus aureus clearance in a murine pulmonary infection model. Blood Adv. 2021.
Dannenmann B, Zahabi A, Mir P, Oswald B, Bernhard R, Klimiankou M, Morishima T, Zeidler C, Kanz L, Lachmann N, et al. Human iPSC-based model of severe congenital neutropenia reveals elevated UPR and DNA damage in CD34 cells preceding leukemic transformation. Exp Hematol. 2019.
Drick N, Dahlmann J, Sahabian A, Haase A, Göhring G, Lachmann N, Ringshausen FC, Welte T, Martin U, Olmer R. Generation of two human induced pluripotent stem cell lines (MHHi017-A, MHHi017-B) from a patient with primary ciliary dyskinesia carrying a homozygous mutation (c.7915C > T [p.Arg2639*]) in the DNAH5 gene. Stem Cell Res. 2020;46:101848.
Dahlmann J, Sahabian A, Drick N, Haase A, Göhring G, Lachmann N, Ringshausen FC, Welte T, Martin U, Olmer R. Generation of two hiPSC lines (MHHi016-A, MHHi016-B) from a primary ciliary dyskinesia patient carrying a homozygous 5 bp duplication (c.248_252dup (p.Gly85Cysfs*11)) in exon 1 of the CCNO gene. Stem Cell Res. 2020;46:101850.
Börger A-K, Eicke D, Wolf C, Gras C, Aufderbeck S, Schulze K, Engels L, Eiz-Vesper B, Schambach A, Guzman CA, et al. Generation of HLA-universal iPSCs-derived megakaryocytes and platelets for survival under refractoriness conditions. Mol Med. 2016;22.
Malainou C, Abdin SM, Lachmann N, Matt U, Herold S. Alveolar macrophages in tissue homeostasis, inflammation, and infection: evolving concepts of therapeutic targeting. J Clin Invest. 2023;133(19).
Hetzel M, Gensch I, Ackermann M, Lachmann N. Adaptation of Human iPSC-Derived Macrophages Toward an Alveolar Macrophage-Like Phenotype Post-Intra-Pulmonary Transfer into Murine Models. Methods Mol Biol. 2024;2713:463-479.