Biblio

Author Title Type [ Year(Desc)]
Filters: Author is Manz, Markus G  [Clear All Filters]
2015
Mager LF, Riether C, Schürch CM, Banz Y, Wasmer M-H, Stuber R, Theocharides AP, Li X, Xia Y, Saito H, et al. IL-33 signaling contributes to the pathogenesis of myeloproliferative neoplasms. J Clin Invest. 2015.
2016
Pietras EM, Mirantes-Barbeito C, Fong S, Loeffler D, Kovtonyuk LV, Zhang S, Lakshminarasimhan R, Chin CPeng, Techner J-M, Will B, et al. Chronic interleukin-1 exposure drives haematopoietic stem cells towards precocious myeloid differentiation at the expense of self-renewal. Nat Cell Biol. 2016.
Luis TC, Tremblay CS, Manz MG, North TE, King KY, Challen G. Inflammatory Signals in HSPC Development and Homeostasis - Too Much of a Good Thing?. Exp Hematol. 2016.
Saito Y, Ellegast JM, Rafiei A, Song Y, Kull D, Heikenwälder M, Rongvaux A, Halene S, Flavell RA, Manz MG. Peripheral blood CD34+ cells efficiently engraft human cytokine knock-in mice. Blood. 2016.
2019
Bourgine PE, Fritsch K, Pigeot S, Takizawa H, Kunz L, Kokkaliaris KD, Coutu DL, Manz MG, Martin I, Schroeder T. Fate Distribution and Regulatory Role of Human Mesenchymal Stromal Cells in Engineered Hematopoietic Bone Organs. iScience. 2019;19:504-513.
Helbling PM, Piñeiro-Yáñez E, Gerosa R, Boettcher S, Al-Shahrour F, Manz MG, Nombela-Arrieta C. Global Transcriptomic Profiling of the Bone Marrow Stromal Microenvironment during Postnatal Development, Aging, and Inflammation. Cell Rep. 2019;29(10):3313-3330.e4.
2020
Myburgh R, Kiefer JD, Russkamp NF, Magnani CF, Nuñez N, Simonis A, Pfister S, C Wilk M, McHugh D, Friemel J, et al. Anti-human CD117 CAR T-cells efficiently eliminate healthy and malignant CD117-expressing hematopoietic cells. Leukemia. 2020.
Boettcher S, C Wilk M, Singer J, Beier F, Burcklen E, Beisel C, Ferreira MSVentura, Gourri E, Gassner C, Frey BM, et al. Clonal hematopoiesis in donors and long-term survivors of related allogeneic hematopoietic stem cell transplantation. Blood. 2020.
C Wilk M, Manz MG, Boettcher S. Clonal hematopoiesis in hematopoietic stem cell transplantation. Curr Opin Hematol. 2020;Publish Ahead of Print.
Shin JJ, Schröder MS, Caiado F, Wyman SK, Bray NL, Bordi M, DeWitt MA, Vu JT, Kim W-T, Hockemeyer D, et al. Controlled Cycling and Quiescence Enables Efficient HDR in Engraftment-Enriched Adult Hematopoietic Stem and Progenitor Cells. Cell Rep. 2020;32(9):108093.
Takizawa H, Fritsch K, Kovtonyuk LV, Saito Y, Yakkala C, Jacobs K, Ahuja AK, Lopes M, Hausmann A, Hardt W-D, et al. Pathogen-Induced TLR4-TRIF Innate Immune Signaling in Hematopoietic Stem Cells Promotes Proliferation but Reduces Competitive Fitness. Cell Stem Cell. 2020;27(1):177.
Giger S, Kovtonyuk LV, Utz SG, Ramosaj M, Kovacs WJ, Schmid E, Ioannidis V, Greter M, Manz MG, Lutolf MP, et al. A Single Metabolite which Modulates Lipid Metabolism Alters Hematopoietic Stem/Progenitor Cell Behavior and Promotes Lymphoid Reconstitution. Stem Cell Reports. 2020.
2021
Russkamp NF, Myburgh R, Kiefer JD, Neri D, Manz MG. Anti-CD117 immunotherapy to eliminate hematopoietic and leukemia stem cells. Exp Hematol. 2021.
Loeffler D, Schneiter F, Wang W, Wehling A, Kull T, Lengerke C, Manz MG, Schroeder T. Asymmetric organelle inheritance predicts human blood stem cell fate. Blood. 2021.
Taromi S, Firat E, Simonis A, Braun LM, Apostolova P, Elze M, Passlick B, Heitzler A, Lagies S, Frey A, et al. Enhanced AC133-specific CAR T cell therapy induces durable remissions in mice with metastatic small cell lung cancer. Cancer Lett. 2021.
2022
Caiado F, Kovtonyuk LV, Gonullu NG, Fullin J, Boettcher S, Manz MG. Aging drives Tet2+/- >clonal hematopoiesis via IL-1 signaling. Blood. 2022.
Taromi S, Firat E, Simonis A, Braun LM, Apostolova P, Elze M, Passlick B, Schumacher A, Lagies S, Frey A, et al. Enhanced AC133-specific CAR T cell therapy induces durable remissions in mice with metastatic small cell lung cancer. Cancer Lett. 2022:215697.
Tan G, Wolski WEryk, Kummer S, Hofstetter MCarina, Theocharides APA, Manz MG, Aebersold R, Meier-Abt F. Proteomic identification of proliferation and progression markers in human polycythemia vera stem and progenitor cells. Blood Adv. 2022.
2023
Magnani CF, Myburgh R, Brunn S, Chambovey M, Ponzo M, Volta L, Manfredi F, Pellegrino C, Pascolo S, Miskey C, et al. Anti-CD117 CAR T cells incorporating a safety switch eradicate human acute myeloid leukemia and hematopoietic stem cells. Mol Ther Oncolytics. 2023;30:56-71.
Lysenko V, Schürch PM, Tuzlak S, van Wijk NWildner-Ve, Kovtonyuk LV, Becher B, Manz MG, Kreutmair S, Theocharides APA. Blocking the CD47-SIRPα interaction reverses the disease phenotype in a polycythemia vera mouse model. Leukemia. 2023.
Magnani CF, Myburgh R, Brunn S, Chambovey M, Ponzo M, Volta L, Manfredi F, Pellegrino C, Pascolo S, Miskey C, et al. Erratum: Anti-CD117 CAR T cells incorporating a safety switch eradicate human acute myeloid leukemia and hematopoietic stem cells. Mol Ther Oncolytics. 2023;30:150.
Ngai LLam, Hanekamp D, Janssen F, Carbaat-Ham J, Hofland MAM, Fayed MMHE, Kelder A, van Marsbergen LOudshoorn-, Scholten WJ, Snel AN, et al. Prospective Validation of the Prognostic Relevance of CD34+CD38- AML Stem Cell frequency in the HOVON-SAKK132 trial. Blood. 2023.
Volta L, Manz MG. Twisted: Escape of epitope-edited healthy cells from immune attack. J Exp Med. 2023;220(12).