Biblio

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Journal Article

Borbaran-Bravo N, Arreba-Tutusaus P, Ritter MU, Nasri M, Klimiankou M, Skokowa J. Regenerative medicine meets translational oncology: Modeling leukemic bone marrow niche. Cell Rep Med. 2022;3(8):100724.

Dannenmann B, Klimiankou M, Oswald B, Solovyeva A, Mardan J, Nasri M, Ritter M, Zahabi A, Arreba-Tutusaus P, Mir P, et al. iPSC modeling of stage-specific leukemogenesis reveals BAALC as a key oncogene in severe congenital neutropenia. Cell Stem Cell. 2021.

Dannenmann B, Zahabi A, Mir P, Oswald B, Bernhard R, Klimiankou M, Morishima T, Zeidler C, Kanz L, Lachmann N, et al. Human iPSC-based model of severe congenital neutropenia reveals elevated UPR and DNA damage in CD34 cells preceding leukemic transformation. Exp Hematol. 2019.

Pogozhykh D, Karapinar DYilmaz, Klimiankou M, Gerschmann N, Ebetsberger-Dachs G, Palmblad J, Carlsson G, Masmas T, Kinsey S, Bartels M, et al. HAX1-related congenital neutropenia: Long-term observation in paediatric and adult patients enrolled in the European branch of the Severe Chronic Neutropenia International Registry (SCNIR). Br J Haematol. 2023.

Mir P, Ritter M, Welte K, Skokowa J, Klimiankou M. Gene Knockout in Hematopoietic Stem and Progenitor Cells Followed by Granulocytic Differentiation. Methods Mol Biol. 2020;2115:455-469.

Zeidler A, Borbaran-Bravo N, Dannenmann B, Ritter M, Nasri M, Klimiankou M, Kandabarau S, Zahabi A, König J, Zeidler C, et al. Differential transcriptional control of hematopoiesis in congenital and cycling neutropenia patients harboring mutations. Haematologica. 2023.

Nasri M, Ritter M, Mir P, Dannenmann B, Kaufmann MM, Arreba-Tutusaus P, Xu Y, Borbaran-Bravo N, Klimiankou M, Lengerke C, et al. CRISPR/Cas9n-mediated ELANE promoter editing for gene therapy of severe congenital neutropenia. Mol Ther. 2024.