Biblio

Author Title [ Type(Desc)] Year
Filters: Author is Giotopoulos, George  [Clear All Filters]
Journal Article
Fong CYew, Gilan O, Lam EYN, Rubin AF, Ftouni S, Tyler D, Stanley K, Sinha D, Yeh P, Morison J, et al. BET inhibitor resistance emerges from leukaemia stem cells. Nature. 2015.
Gallipoli P, Giotopoulos G, Huntly BJP. Epigenetic regulators as promising therapeutic targets in acute myeloid leukemia. Ther Adv Hematol. 2015;6(3):103-119.
Agrawal-Singh S, Bagri J, Giotopoulos G, Azazi D, Horton SJ, Lopez CK, Anand S, Bach A-S, Stedham F, Antrobus R, et al. HOXA9 forms a repressive complex with nuclear matrix-associated protein SAFB to maintain acute myeloid leukemia. Blood. 2022.
Lara-Astiaso D, Goñi-Salaverri A, Mendieta-Esteban J, Narayan N, Del Valle C, Gross T, Giotopoulos G, Beinortas T, Navarro-Alonso M, Aguado-Alvaro LPilar, et al. In vivo screening characterizes chromatin factor functions during normal and malignant hematopoiesis. Nat Genet. 2023.
Giotopoulos G, Huntly BJP. Intratumoral Heterogeneity: Tools to Understand and Exploit Clone Wars in AML. Cancer Cell. 2018;34(4):533-535.
Arede L, Foerner E, Wind SSterre, Kulkarni R, Domingues AFilipa, Giotopoulos G, Kleinwächter S, Mollenhauer-Starkl M, Davison H, Chandru A, et al. KAT2A complexes ATAC and SAGA play unique roles in cell maintenance and identity in hematopoiesis and leukemia. Blood Adv. 2021.
Isobe T, Kucinski I, Barile M, Wang X, Hannah R, Bastos HP, Chabra S, Vijayabaskar MS, Sturgess KHM, Williams MJ, et al. Preleukemic single-cell landscapes reveal mutation-specific mechanisms and gene programs predictive of AML patient outcomes. Cell Genom. 2023;3(12):100426.
Gong C, Krupka JA, Gao J, Grigoropoulos NF, Giotopoulos G, Asby R, Screen M, Usheva Z, Cucco F, Barrans S, et al. Sequential inverse dysregulation of the RNA helicases DDX3X and DDX3Y facilitates MYC-driven lymphomagenesis. Mol Cell. 2021.
Gupta S, Dovey OM, Domingues AFilipa, Cyran OW, Cash CM, Giotopoulos G, Rak J, Cooper J, Gozdecka M, Dijkhuis L, et al. Transcriptional variability accelerates preleukemia by cell diversification and perturbation of protein synthesis. Sci Adv. 2022;8(31):eabn4886.