Biblio

Author Title Type [ Year(Asc)]
Filters: Author is Clevers, Hans  [Clear All Filters]
2021
Geurts MH, van der Vaart J, Beumer J, Clevers H. The Organoid Platform: Promises and Challenges as Tools in the Fight against COVID-19. Stem Cell Reports. 2021;16(3):412-418.
Lu C, Lin X, Yamashita J, Xi R, Zhou M, Zhang YV, Wang H, Margolskee RF, Koo B-K, Clevers H, et al. RNF43/ZNRF3 negatively regulates taste tissue homeostasis and positively regulates dorsal lingual epithelial tissue homeostasis. Stem Cell Reports. 2021.
Kretzschmar K, Boonekamp KE, Bleijs M, Asra P, Koomen M, Lopes SMChuva de, Giovannone B, Clevers H. Troy/Tnfrsf19 marks epidermal cells that govern interfollicular epidermal renewal and cornification. Stem Cell Reports. 2021.
2020
Murata K, Jadhav U, Madha S, van Es J, Dean J, Cavazza A, Wucherpfennig K, Michor F, Clevers H, Shivdasani RA. Ascl2-Dependent Cell Dedifferentiation Drives Regeneration of Ablated Intestinal Stem Cells. Cell Stem Cell. 2020.
Geurts MH, de Poel E, Amatngalim GD, Oka R, Meijers FM, Kruisselbrink E, van Mourik P, Berkers G, de Groot KM de Winte, Michel S, et al. CRISPR-Based Adenine Editors Correct Nonsense Mutations in a Cystic Fibrosis Organoid Biobank. Cell Stem Cell. 2020.
Joosten SPJ, Spaargaren M, Clevers H, Pals ST. Hepatocyte growth factor/MET and CD44 in colorectal cancer: partners in tumorigenesis and therapy resistance. Biochim Biophys Acta Rev Cancer. 2020:188437.
Hageman JH, Heinz MC, Kretzschmar K, van der Vaart J, Clevers H, Snippert HJG. Intestinal Regeneration: Regulation by the Microenvironment. Dev Cell. 2020;54(4):435-446.
Rajewsky N, Almouzni G, Gorski SA, Aerts S, Amit I, Bertero MG, Bock C, Bredenoord AL, Cavalli G, Chiocca S, et al. LifeTime and improving European healthcare through cell-based interceptive medicine. Nature. 2020.
Gao Y, Yan Y, Tripathi S, Pentinmikko N, Amaral A, Päivinen P, Domènech-Moreno E, Andersson S, Wong IPL, Clevers H, et al. LKB1 Represses ATOH1 via PDK4 and Energy Metabolism and Regulates Intestinal Stem Cell Fate. Gastroenterology. 2020.
2019
Post Y, Clevers H. Defining Adult Stem Cell Function at Its Simplest: The Ability to Replace Lost Cells through Mitosis. Cell Stem Cell. 2019;25(2):174-183.
Schneeberger K, Sánchez-Romero N, Ye S, van Steenbeek FG, Oosterhoff LA, Palacin IPla, Chen C, van Wolferen ME, van Tienderen G, Lieshout R, et al. Large-scale Production of LGR5-positive Bipotential Human Liver Stem Cells. Hepatology. 2019.
Joosten SPJ, Mizutani T, Spaargaren M, Clevers H, Pals ST. MET signaling overcomes EGFR inhibition in normal and colorectal cancer stem cells causing drug resistance. Gastroenterology. 2019.
Dekkers JF, Whittle JR, Vaillant F, Chen H-R, Dawson C, Liu K, Geurts M, Herold MJ, Clevers H, Lindeman GJ, et al. Modeling breast cancer using CRISPR/Cas9-mediated engineering of human breast organoids. J Natl Cancer Inst. 2019.
Clevers H, Conder RK, Li VSW, Lutolf MP, Vallier L, Chan S, Grikscheit TC, Jensen KB, De Coppi P. Tissue-Engineering the Intestine: The Trials before the Trials. Cell Stem Cell. 2019;24(6):855-859.
2018
Aden K, Bartsch K, Dahl J, Reijns MAM, Esser D, Sheibani-Tezerji R, Sinha A, Wottawa F, Ito G, Mishra N, et al. Epithelial RNase H2 Maintains Genome Integrity and Prevents Intestinal Tumorigenesis in Mice. Gastroenterology. 2018.
Fujii M, Clevers H, Sato T. Modeling Human Digestive Diseases with CRISPR-Cas9-modified Organoids. Gastroenterology. 2018.
Schmitt M, Schewe M, Sacchetti A, Feijtel D, van de Geer WS, Teeuwssen M, Sleddens HF, Joosten R, van Royen ME, van de Werken HJG, et al. Paneth Cells Respond to Inflammation and Contribute to Tissue Regeneration by Acquiring Stem-like Features through SCF/c-Kit Signaling. Cell Rep. 2018;24(9):2312-2328.e7.
Chan LHei, Zhou L, Ng KYu, Wong TLok, Lee TK, Sharma R, Loong JH, Ching YPang, Yuan Y-F, Xie D, et al. PRMT6 Regulates RAS/RAF Binding and MEK/ERK-Mediated Cancer Stemness Activities in Hepatocellular Carcinoma through CRAF Methylation. Cell Rep. 2018;25(3):690-701.e8.
Sasaki N, Clevers H. Studying cellular heterogeneity and drug sensitivity in colorectal cancer using organoid technology. Curr Opin Genet Dev. 2018;52:117-122.
2016
Broutier L, Andersson-Rolf A, Hindley CJ, Boj SF, Clevers H, Koo B-K, Huch M. Culture and establishment of self-renewing human and mouse adult liver and pancreas 3D organoids and their genetic manipulation. Nat Protoc. 2016;11(9):1724-1743.
Clevers H. Modeling Development and Disease with Organoids. Cell. 2016;165(7):1586-1597.
Kretzschmar K, Clevers H. Organoids: Modeling Development and the Stem Cell Niche in a Dish. Dev Cell. 2016;38(6):590-600.
Beumer J, Clevers H. Regulation and plasticity of intestinal stem cells during homeostasis and regeneration. Development. 2016;143(20):3639-3649.
Visvader JE, Clevers H. Tissue-specific designs of stem cell hierarchies. Nat Cell Biol. 2016.
Farin HF, Jordens I, Mosa MH, Basak O, Korving J, Tauriello DVF, de Punder K, Angers S, Peters PJ, Maurice MM, et al. Visualization of a short-range Wnt gradient in the intestinal stem-cell niche. Nature. 2016.

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