Biblio

Author Title Type [ Year(Asc)]
Filters: Author is Patani, Rickie  [Clear All Filters]
2024
Hung C, Patani R. 4R MAPT/tau drives endolysosomal and autophagy dysfunction in frontotemporal dementia. Autophagy. 2024.
Hung C, Fertan E, Livesey FJ, Klenerman D, Patani R. APP antisense oligonucleotides reduce Aβ aggregation and rescue endolysosomal dysfunction in Alzheimer's disease. Brain. 2024.
2023
Hung C, Patani R. Elevated 4R tau contributes to endolysosomal dysfunction and neurodegeneration in VCP-related frontotemporal dementia. Brain. 2023.
Patani R, Hardingham GE, Liddelow SA. Functional roles of reactive astrocytes in neuroinflammation and neurodegeneration. Nat Rev Neurol. 2023.
Ziff OJ, Neeves J, Mitchell J, Tyzack G, Martínez-Ruiz C, Luisier R, Chakrabarti AM, McGranahan N, Litchfield K, Boulton SJ, et al. Integrated transcriptome landscape of ALS identifies genome instability linked to TDP-43 pathology. Nat Commun. 2023;14(1):2176.
Alam A, Singh T, Kayhanian S, Tjerkaski J, Garcia NMarco, Carpenter K, Patani R, Lindblad C, Thelin EPeter, Syed YAhmed, et al. Modelling the inflammatory response of traumatic brain injury using human induced pluripotent stem cell derived microglia. J Neurotrauma. 2023.
Ziff OJ, Harley J, Wang Y, Neeves J, Tyzack G, Ibrahim F, Skehel M, Chakrabarti AM, Kelly G, Patani R. Nucleocytoplasmic mRNA redistribution accompanies RNA binding protein mislocalization in ALS motor neurons and is restored by VCP ATPase inhibition. Neuron. 2023.
2021
Ziff OJ, Taha DM, Crerar H, Clarke BE, Chakrabarti AM, Kelly G, Neeves J, Tyzack GE, Luscombe NM, Patani R. Reactive astrocytes in ALS display diminished intron retention. Nucleic Acids Res. 2021.
2020
Smethurst P, Risse E, Tyzack GE, Mitchell JS, Taha DM, Chen Y-R, Newcombe J, Collinge J, Sidle K, Patani R. Distinct responses of neurons and astrocytes to TDP-43 proteinopathy in amyotrophic lateral sclerosis. Brain. 2020;143(2):430-440.