Biblio

Author Title Type [ Year(Desc)]
Filters: Author is Brennand, Kristen J  [Clear All Filters]
2015
Mertens J, Wang Q-W, Kim Y, Yu DX, Pham S, Yang B, Zheng Y, Diffenderfer KE, Zhang J, Soltani S, et al. Differential responses to lithium in hyperexcitable neurons from patients with bipolar disorder. Nature. 2015.
Topol A, Tran NN, Brennand KJ. A Guide to Generating and Using hiPSC Derived NPCs for the Study of Neurological Diseases. J Vis Exp. 2015;(96).
2016
Roussos P, Guennewig B, Kaczorowski DC, Barry G, Brennand KJ. Activity-Dependent Changes in Gene Expression in Schizophrenia Human-Induced Pluripotent Stem Cell Neurons. JAMA Psychiatry. 2016.
Hartley BJ, Brennand KJ. Neural organoids for disease phenotyping, drug screening and developmental biology studies. Neurochem Int. 2016.
2019
Halpern M, Brennand KJ, Gregory J. Examining the relationship between astrocyte dysfunction and neurodegeneration in ALS using hiPSCs. Neurobiol Dis. 2019:104562.
Flaherty E, Zhu S, Barretto N, Cheng E, Deans PJMichael, Fernando MB, Schrode N, Francoeur N, Antoine A, Alganem K, et al. Neuronal impact of patient-specific aberrant NRXN1α splicing. Nat Genet. 2019;51(12):1679-1690.
2020
Barretto N, Zhang H, Powell SK, Fernando MB, Zhang S, Flaherty EK, Ho S-M, Slesinger PA, Duan J, Brennand KJ. ASCL1- and DLX2-induced GABAergic neurons from hiPSC-derived NPCs. J Neurosci Methods. 2020;334:108548.
Fernando MB, Ahfeldt T, Brennand KJ. Modeling the complex genetic architectures of brain disease. Nat Genet. 2020.
Wang M, Li A, Sekiya M, Beckmann ND, Quan X, Schrode N, Fernando MB, Yu A, Zhu L, Cao J, et al. Transformative Network Modeling of Multi-omics Data Reveals Detailed Circuits, Key Regulators, and Potential Therapeutics for Alzheimer's Disease. Neuron. 2020.
2021
Deans PJames Mich, Brennand KJ. Applying stem cells and CRISPR engineering to uncover the etiology of schizophrenia. Curr Opin Neurobiol. 2021;69:193-201.
2022
Hafez AK, Zimmerman AJ, Papageorgiou G, Chandrasekaran J, Amoah SK, Lin R, Lozano E, Pierotti C, Dell'Orco M, Hartley BJ, et al. A bidirectional competitive interaction between circHomer1 and Homer1b within the orbitofrontal cortex regulates reversal learning. Cell Rep. 2022;38(3):110282.
Seah C, Huckins LM, Brennand KJ. Stem Cell Models for Context-Specific Modeling in Psychiatric Disorders. Biol Psychiatry. 2022.
2023
Ma Y, Bendl J, Hartley BJ, Fullard JF, Abdelaal R, Ho S-M, Kosoy R, Gochman P, Rapoport J, Hoffman GE, et al. Activity-Dependent Transcriptional Program in NGN2+ Neurons Enriched for Genetic Risk for Brain-Related Disorders. Biol Psychiatry. 2023.
Rahman S, Dong P, Apontes P, Fernando MB, Kosoy R, Townsley KG, Girdhar K, Bendl J, Shao Z, Misir R, et al. Lineage specific 3D genome structure in the adult human brain and neurodevelopmental changes in the chromatin interactome. Nucleic Acids Res. 2023.
Fernando MB, Fan Y, Zhang Y, Kammourh S, Murphy AN, Ghorbani S, Onatzevitch R, Pero A, Padilla C, Cao L, et al. Precise Therapeutic Targeting of Distinct Mutations. bioRxiv. 2023.
2024
Brennand KJ. Aligning Stem Cell Models and Postmortem Studies to Query Striatal Neurodevelopment in Schizophrenia. Am J Psychiatry. 2024;181(6):465-467.
Stern S, Zhang L, Wang M, Wright R, Rosh I, Hussein Y, Stern T, Choudhary A, Tripathi U, Reed P, et al. Monozygotic twins discordant for schizophrenia differ in maturation and synaptic transmission. Mol Psychiatry. 2024.