Biblio

Author Title Type [ Year(Desc)]
Filters: Author is Karuppagounder, Senthilkumar S  [Clear All Filters]
2014
Lu W, Karuppagounder SS, Springer DA, Allen MD, Zheng L, Chao B, Zhang Y, Dawson VL, Dawson TM, Lenardo M. Genetic deficiency of the mitochondrial protein PGAM5 causes a Parkinson's-like movement disorder. Nat Commun. 2014;5:4930.
2021
Seo BAm, Kim D, Hwang H, Kim MSeong, Ma S-X, Kwon S-H, Kweon SHo, Wang H, Yoo JMin, Choi S, et al. TRIP12 ubiquitination of glucocerebrosidase contributes to neurodegeneration in Parkinson's disease. Neuron. 2021.
2022
Scott L, Karuppagounder SS, Neifert S, Kang BGu, Wang H, Dawson VL, Dawson TM. The absence of Parkin does not promote dopamine or mitochondrial dysfunction in PolgA mitochondrial mutator mice. J Neurosci. 2022.
Panicker N, Kam T-I, Wang H, Neifert S, Chou S-C, Kumar M, Brahmachari S, Jhaldiyal A, Hinkle JT, Akkentli F, et al. Neuronal NLRP3 is a parkin substrate that drives neurodegeneration in Parkinson's disease. Neuron. 2022.
Park H, Kam T-I, Peng H, Chou S-C, Mehrabani-Tabari AA, Song J-J, Yin X, Karuppagounder SS, Umanah GK, Rao AVSubba, et al. PAAN/MIF nuclease inhibition prevents neurodegeneration in Parkinson's disease. Cell. 2022.
2023
Washington-Hughes CL, Roy S, Seneviratne HKamal, Karuppagounder SS, Morel Y, Jones JW, Zak A, Xiao T, Boronina TN, Cole RN, et al. Atp7b-dependent choroid plexus dysfunction Causes transient copper deficit and metabolic changes in the developing mouse brain. PLoS Genet. 2023;19(1):e1010558.
Karuppagounder SS, Wang H, Kelly T, Rush R, Nguyen R, Bisen S, Yamashita Y, Sloan N, Dang B, Sigmon A, et al. The c-Abl inhibitor IkT-148009 suppresses neurodegeneration in mouse models of heritable and sporadic Parkinson's disease. Sci Transl Med. 2023;15(679):eabp9352.