Biblio

Author Title Type [ Year(Asc)]
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2024
Mizokami H, Okabe A, Choudhary R, Mima M, Saeda K, Fukuyo M, Rahmutulla B, Seki M, Goh B-C, Kondo S, et al. Enhancer infestation drives tumorigenic activation of inactive B compartment in Epstein-Barr virus-positive nasopharyngeal carcinoma. EBioMedicine. 2024;102:105057.
2023
Choo J, Kua LFang, Soe MYar, Asuncion BReyna, Tan BKye Jyn, Teo CBoon, Tay RYong Kiat, So J, Shabbir A, Guowei K, et al. Clinical relevance of PD-1 positive CD8 T-cells in gastric cancer. Gastric Cancer. 2023.
Xu C, Huang KKyon, Law JHao, Chua JShijia, Sheng T, Flores NM, Pizzi MPool, Okabe A, Tan ALay Keng, Zhu F, et al. Comprehensive molecular phenotyping of -deficient gastric cancer reveals pervasive epigenomic reprogramming and therapeutic opportunities. Gut. 2023.
Fan Q, Li H, Wang X, Tham Y-C, Teo KYi Chong, Yasuda M, Lim WKhong, Kwan YPing, Teo JXian, Chen C-J, et al. Contribution of common and rare variants to Asian neovascular age-related macular degeneration subtypes. Nat Commun. 2023;14(1):5574.
Kuderna LFK, Gao H, Janiak MC, Kuhlwilm M, Orkin JD, Bataillon T, Manu S, Valenzuela A, Bergman J, Rousselle M, et al. A global catalog of whole-genome diversity from 233 primate species. Science. 2023;380(6648):906-913.
Tham C-Y, Poon LF, Yan T, Koh JYu Peng, Ramlee MKhairul, Teoh VSwee Imm, Zhang S, Cai Y, Hong Z, Lee GS, et al. High-throughput telomere length measurement at nucleotide resolution using the PacBio high fidelity sequencing platform. Nat Commun. 2023;14(1):281.
Kuderna LFK, Ulirsch JC, Rashid S, Ameen M, Sundaram L, Hickey G, Cox AJ, Gao H, Kumar A, Aguet F, et al. Identification of constrained sequence elements across 239 primate genomes. Nature. 2023.
Usui G, Matsusaka K, Huang KKyon, Zhu F, Shinozaki T, Fukuyo M, Rahmutulla B, Yogi N, Okada T, Minami M, et al. Integrated environmental, lifestyle, and epigenetic risk prediction of primary gastric neoplasia using the longitudinally monitored cohorts. EBioMedicine. 2023;98:104844.
Hong JHan, Yong CHan, Heng HLee, Chan JYongsheng, Lau MChan, Chen J, Lee JYi, Lim AHerbert, Li Z, Guan P, et al. Integrative multiomics enhancer activity profiling identifies therapeutic vulnerabilities in cholangiocarcinoma of different etiologies. Gut. 2023.
Gao H, Hamp T, Ede J, Schraiber JG, McRae J, Singer-Berk M, Yang Y, Dietrich ASD, Fiziev PP, Kuderna LFK, et al. The landscape of tolerated genetic variation in humans and primates. Science. 2023;380(6648):eabn8153.
Yonemura A, Semba T, Zhang J, Fan Y, Yasuda-Yoshihara N, Wang H, Uchihara T, Yasuda T, Nishimura A, Fu L, et al. Mesothelial cells with mesenchymal features enhance peritoneal dissemination by forming a protumorigenic microenvironment. Cell Rep. 2023:113613.
Wong E, Bertin N, Hebrard M, Tirado-Magallanes R, Bellis C, Lim WKhong, Chua CYong, Tong PMei Lin, Chua R, Mak K, et al. The Singapore National Precision Medicine Strategy. Nat Genet. 2023.
Tan P, Chu Y. Single-cell profiling of gastric cardia adenocarcinoma reveals drivers of cancer stemness and therapeutic targets. Gut. 2023.
2022
Chan SHoai, Bylstra Y, Teo JXian, Kuan JLing, Bertin N, Gonzalez-Porta M, Hebrard M, Tirado-Magallanes R, Tan JHui Juan, Jeyakani J, et al. Analysis of clinically relevant variants from ancestrally diverse Asian genomes. Nat Commun. 2022;13(1):6694.
Gwee YXiang, Chia DKai Ann, So J, Ceelen W, Yong WPeng, Tan P, Ong C-AJohnny, Sundar R. Integration of Genomic Biology Into Therapeutic Strategies of Gastric Cancer Peritoneal Metastasis. J Clin Oncol. 2022:JCO2102745.
Ho SWei Ting, Sheng T, Xing M, Ooi WFong, Xu C, Sundar R, Huang KKyon, Li Z, Kumar V, Ramnarayanan K, et al. Regulatory enhancer profiling of mesenchymal-type gastric cancer reveals subtype-specific epigenomic landscapes and targetable vulnerabilities. Gut. 2022.
2021
Li W, Okabe A, Usui G, Fukuyo M, Matsusaka K, Rahmutulla B, Mano Y, Hoshii T, Funata S, Hiura N, et al. Activation of EHF via STAT3 phosphorylation by LMP2A in Epstein-Barr virus-positive gastric cancer. Cancer Sci. 2021.
Yasuda T, Koiwa M, Yonemura A, Miyake K, Kariya R, Kubota S, Yokomizo-Nakano T, Yasuda-Yoshihara N, Uchihara T, Itoyama R, et al. Inflammation-driven senescence-associated secretory phenotype in cancer-associated fibroblasts enhances peritoneal dissemination. Cell Rep. 2021;34(8):108779.
2020
Xing M, Ooi WFong, Tan J, Qamra A, Lee P-H, Li Z, Xu C, Padmanabhan N, Lim JQuan, Guo YAmanda, et al. Genomic and epigenomic EBF1 alterations modulate TERT expression in gastric cancer. J Clin Invest. 2020.
Kongpetch S, Jusakul A, Lim JQuan, Ng CChuan Youn, Chan JYongsheng, Rajasegaran V, Lim THui, Lim KHon, Choo SPin, Dima S, et al. Lack of Targetable FGFR2 Fusions in Endemic Fluke-Associated Cholangiocarcinoma. JCO Glob Oncol. 2020;6:628-638.
2019
Xiong L, Wu F, Wu Q, Xu L, Cheung OK, Kang W, Mok MT, Szeto LLM, Lun C-Y, Lung RW, et al. Aberrant enhancer hypomethylation contributes to hepatic carcinogenesis through global transcriptional reprogramming. Nat Commun. 2019;10(1):335.
Ho SWei Ting, Tan P. Dissection of Gastric Cancer Heterogeneity for Precision Oncology. Cancer Sci. 2019.
Ooi WFong, Nargund AM, Lim KJunliang, Zhang S, Xing M, Mandoli A, Lim JQuan, Ho SWei Ting, Guo Y, Yao X, et al. Integrated paired-end enhancer profiling and whole-genome sequencing reveals recurrent and enhancer hijacking in primary gastric adenocarcinoma. Gut. 2019.
Zhang Y, Koe CTat, Tan YSing, Ho J, Tan P, Yu F, Sung W-K, Wang H. The Integrator Complex Prevents Dedifferentiation of Intermediate Neural Progenitors back into Neural Stem Cells. Cell Rep. 2019;27(4):987-996.e3.
Wu D, Dou J, Chai X, Bellis C, Wilm A, Shih CChuan, Soon WWei Jia, Bertin N, Lin CBitong, Khor CChuen, et al. Large-Scale Whole-Genome Sequencing of Three Diverse Asian Populations in Singapore. Cell. 2019;179(3):736-749.e15.

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