Biblio
Analysis of proteome-wide degradation dynamics in ALS SOD1 iPSC-derived patient neurons reveals disrupted VCP homeostasis. Cell Rep. 2023:113160.
C9ORF72 protein function and immune dysregulation in amyotrophic lateral sclerosis. Neurosci Lett. 2019:134523.
. The C9ORF72 repeat expansion alters neurodevelopment. Cell Rep. 2023;42(8):112983.
Central role for PICALM in amyloid-β blood-brain barrier transcytosis and clearance. Nat Neurosci. 2015.
CLIP-Seq analysis enables the design of protective ribosomal RNA bait oligonucleotides against ALS/FTD poly-GR pathophysiology. Sci Adv. 2023;9(45):eadf7997.
Deep learning modeling of rare noncoding genetic variants in human motor neurons defines as a therapeutic target for ALS. medRxiv. 2024.
Directly Reprogrammed Neurons Still Have Some Growing Up to Do. Cell Stem Cell. 2019;25(1):1-2.
. Downregulation of Hsp90 and the antimicrobial peptide Mtk suppresses poly(GR)-induced neurotoxicity in C9ORF72-ALS/FTD. Neuron. 2023.
Efficient Generation and Transcriptomic Profiling of Human iPSC-Derived Pulmonary Neuroendocrine Cells. iScience. 2020;23(5):101083.
ELAVL4, splicing, and glutamatergic dysfunction precede neuron loss in MAPT mutation cerebral organoids. Cell. 2021.
Identification and therapeutic rescue of autophagosome and glutamate receptor defects in C9ORF72 and sporadic ALS neurons. JCI Insight. 2019;5.
Modeling pain in vitro using nociceptor neurons reprogrammed from fibroblasts. Nat Neurosci. 2014.
Nanog-Independent Reprogramming to iPSCs with Canonical Factors. Stem Cell Reports. 2014;2(2):119-26.
. . Radiogenomics of expansion carriers reveals global transposable element de-repression and enables prediction of thalamic atrophy and clinical impairment. J Neurosci. 2022.
Transcriptomic analysis of feeder-free culture system for maintaining naïve-state pluripotency in human pluripotent stem cells. Stem Cell Investig. 2023;10:10.
. β-Catenin Functions Pleiotropically in Differentiation and Tumorigenesis in Mouse Embryo-Derived Stem Cells. PLoS One. 2013;8(5):e63265.