Biblio
Cell-type specific defects in PTEN-mutant cortical organoids converge on abnormal circuit activity. Hum Mol Genet. 2023.
A Congenital Anemia Reveals Distinct Targeting Mechanisms for Master Transcription Factor GATA1. Blood. 2022.
Core Circadian Clock Genes Regulate Leukemia Stem Cells in AML. Cell. 2016;165(2):303-316.
DNA methylation dynamics of the human preimplantation embryo. Nature. 2014;511(7511):611-615.
. A genetic disorder reveals a hematopoietic stem cell regulatory network co-opted in leukemia. Nat Immunol. 2022.
Heterochronic parabiosis reprograms the mouse brain transcriptome by shifting aging signatures in multiple cell types. Nat Aging. 2023;3(3):327-345.
Heterogeneous Responses of Hematopoietic Stem Cells to Inflammatory Stimuli Are Altered with Age. Cell Rep. 2018;25(11):2992-3005.e5.
The Human Lung Cell Atlas - A high-resolution reference map of the human lung in health and disease. Am J Respir Cell Mol Biol. 2019.
An integrated taxonomy for monogenic inflammatory bowel disease. Gastroenterology. 2021.
Ketone Body Signaling Mediates Intestinal Stem Cell Homeostasis and Adaptation to Diet. Cell. 2019;178(5):1115-1131.e15.
The MicroRNA-132 and MicroRNA-212 Cluster Regulates Hematopoietic Stem Cell Maintenance and Survival with Age by Buffering FOXO3 Expression. Immunity. 2015;42(6):1021-1032.
Prediction of single-cell RNA expression profiles in live cells by Raman microscopy with Raman2RNA. Nat Biotechnol. 2024.
Proper acquisition of cell class identity in organoids allows definition of fate specification programs of the human cerebral cortex. Cell. 2022;185(20):3770-3788.e27.
A Roadmap for the Human Gut Cell Atlas. Nat Rev Gastroenterol Hepatol. 2023.
Single-Cell RNA-Seq Reveals Cellular Hierarchies and Impaired Developmental Trajectories in Pediatric Ependymoma. Cancer Cell. 2020;38(1):44-59.e9.
Spatial reconstruction of single-cell gene expression data. Nat Biotechnol. 2015.
. Systematic benchmarking of single-cell ATAC-sequencing protocols. Nat Biotechnol. 2023.
TACCO unifies annotation transfer and decomposition of cell identities for single-cell and spatial omics. Nat Biotechnol. 2023.
. Transcriptional States and Chromatin Accessibility Underlying Human Erythropoiesis. Cell Rep. 2019;27(11):3228-3240.e7.
Transcriptome Analysis Identifies Regulators of Hematopoietic Stem and Progenitor Cells. Stem Cell Reports. 2013;1(3):266-280.
Voices of biotech. Nat Biotechnol. 2016;34(3):270-275.