Biblio
Cell-type specific defects in PTEN-mutant cortical organoids converge on abnormal circuit activity. Hum Mol Genet. 2023.
Heterochronic parabiosis reprograms the mouse brain transcriptome by shifting aging signatures in multiple cell types. Nat Aging. 2023;3(3):327-345.
A Roadmap for the Human Gut Cell Atlas. Nat Rev Gastroenterol Hepatol. 2023.
Systematic benchmarking of single-cell ATAC-sequencing protocols. Nat Biotechnol. 2023.
. A Congenital Anemia Reveals Distinct Targeting Mechanisms for Master Transcription Factor GATA1. Blood. 2022.
A genetic disorder reveals a hematopoietic stem cell regulatory network co-opted in leukemia. Nat Immunol. 2022.
Proper acquisition of cell class identity in organoids allows definition of fate specification programs of the human cerebral cortex. Cell. 2022;185(20):3770-3788.e27.
An integrated taxonomy for monogenic inflammatory bowel disease. Gastroenterology. 2021.
Single-Cell RNA-Seq Reveals Cellular Hierarchies and Impaired Developmental Trajectories in Pediatric Ependymoma. Cancer Cell. 2020;38(1):44-59.e9.
The Human Lung Cell Atlas - A high-resolution reference map of the human lung in health and disease. Am J Respir Cell Mol Biol. 2019.
Ketone Body Signaling Mediates Intestinal Stem Cell Homeostasis and Adaptation to Diet. Cell. 2019;178(5):1115-1131.e15.
Transcriptional States and Chromatin Accessibility Underlying Human Erythropoiesis. Cell Rep. 2019;27(11):3228-3240.e7.
Heterogeneous Responses of Hematopoietic Stem Cells to Inflammatory Stimuli Are Altered with Age. Cell Rep. 2018;25(11):2992-3005.e5.
Core Circadian Clock Genes Regulate Leukemia Stem Cells in AML. Cell. 2016;165(2):303-316.
Voices of biotech. Nat Biotechnol. 2016;34(3):270-275.
The MicroRNA-132 and MicroRNA-212 Cluster Regulates Hematopoietic Stem Cell Maintenance and Survival with Age by Buffering FOXO3 Expression. Immunity. 2015;42(6):1021-1032.
Spatial reconstruction of single-cell gene expression data. Nat Biotechnol. 2015.
. DNA methylation dynamics of the human preimplantation embryo. Nature. 2014;511(7511):611-615.
. Transcriptome Analysis Identifies Regulators of Hematopoietic Stem and Progenitor Cells. Stem Cell Reports. 2013;1(3):266-280.