Biblio

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Journal Article

Pang L, Sager P, Yang X, Shi H, Sannajust F, Brock M, Wu JC, Abi-Gerges N, Lyn-Cook B, Berridge BR, et al. Workshop Report: FDA Workshop on Improving Cardiotoxicity Assessment With Human-Relevant Platforms. Circ Res. 2019;125(9):855-867.

De Jong HN, Dewey FE, Cordero P, Victorio RA, Kirillova A, Huang Y, Madhvani R, Seo K, Werdich AA, Lan F, et al. Wnt Signaling Interactor WTIP (Wilms Tumor Interacting Protein) Underlies Novel Mechanism for Cardiac Hypertrophy. Circ Genom Precis Med. 2022:101161CIRCGEN121003563.

Buikema JW, Lee S, Goodyer WR, Maas RG, Chirikian O, Li G, Miao Y, Paige SL, Lee D, Wu H, et al. Wnt Activation and Reduced Cell-Cell Contact Synergistically Induce Massive Expansion of Functional Human iPSC-Derived Cardiomyocytes. Cell Stem Cell. 2020;27(1):50-63.e5.

Abi-Gerges N, McMahon C, Vargas H, Sager P, Chui R, Stevens D, Davila J, Schaub JR, Wu JC, Del Rio C, et al. The West coast regional safety pharmacology society meeting update: Filling translational gaps in safety assessment. J Pharmacol Toxicol Methods. 2019:106582.

Eguchi A, Gonzalez AFernanda G, Torres-Bigio SI, Koleckar K, Birnbaum F, Zhang JZ, Wang VY, Wu JC, Artandi SE, Blau HM. TRF2 rescues telomere attrition and prolongs cell survival in Duchenne muscular dystrophy cardiomyocytes derived from human iPSCs. Proc Natl Acad Sci U S A. 2023;120(6):e2209967120.

Wu JC, Garg P, Yoshida Y, Yamanaka S, Gepstein L, Hulot J-S, Knollmann BC, Schwartz PJ. Towards Precision Medicine With Human iPSCs for Cardiac Channelopathies. Circ Res. 2019;125(6):653-658.

Tu C, Caudal A, Liu Y, Gorgodze N, Zhang H, Lam CKeung, Dai Y, Zhang A, Wnorowski A, Wu MA, et al. Tachycardia-induced metabolic rewiring as a driver of contractile dysfunction. Nat Biomed Eng. 2023.

Lau E, Paik DT, Wu JC. Systems-Wide Approaches in Induced Pluripotent Stem Cell Models. Annu Rev Pathol. 2018.

Wang YJessie, Zhang X, Lam CKeung, Guo H, Wang C, Zhang S, Wu JC, Snyder M, Li J. Systems analysis of de novo mutations in congenital heart diseases identified a protein network in the hypoplastic left heart syndrome. Cell Syst. 2022.

Belbachir N, Wu Y, Shen M, Zhang SL, Zhang JZ, Liu C, Knollmann BC, Lyon GJ, Ma N, Wu JC. Studying Long QT Syndrome Caused by Genetic Variants Using Patient-Derived Induced Pluripotent Stem Cells. Circulation. 2023;148(20):1598-1601.

Shen M, Liu C, Zhao SRui, Manhas A, Sundaram L, Ameen M, Wu JC. Stepwise Generation of Human Induced Pluripotent Stem Cell-Derived Cardiac Pericytes to Model Coronary Microvascular Dysfunction. Circulation. 2023;147(6):515-518.

Liu C, Shen M, Tan WLW, Chen IY, Liu Y, Yu X, Yang H, Zhang A, Liu Y, Zhao M-T, et al. Statins improve endothelial function via suppression of epigenetic-driven EndMT. Nat Cardiovasc Res. 2023;2(5):467-485.

Lau E, Han Y, Williams DR, Thomas CT, Shrestha R, Wu JC, P Y Lam M. Splice-Junction-Based Mapping of Alternative Isoforms in the Human Proteome. Cell Rep. 2019;29(11):3751-3765.e5.

Jabart E, Molho J, Sin K, Stansfield B, Kazmouz SG, Ventro D, Gardner K, Wu JC, Churko JM. Single-cell protein expression of hiPSC-derived cardiomyocytes using Single-Cell Westerns. J Mol Cell Cardiol. 2020.

Paik KJ, Maan ZN, Zielins ER, Duscher D, Whittam AJ, Morrison SD, Brett EA, Ransom RC, Hu MS, Wu JC, et al. Short Hairpin RNA Silencing of PHD-2 Improves Neovascularization and Functional Outcomes in Diabetic Wounds and Ischemic Limbs. PLoS One. 2016;11(3):e0150927.

Guo H, Yu X, Liu Y, Paik DT, Justesen JMarie, Chandy M, Jahng JWS, Zhang T, Wu W, Rwere F, et al. SGLT2 inhibitor ameliorates endothelial dysfunction associated with the common alcohol flushing variant. Sci Transl Med. 2023;15(680):eabp9952.

Sharma A, Diecke S, Zhang WY, Lan F, He C, Mordwinkin NM, Chua KF, Wu JC. Role of SIRT6 in Aging and Reprogramming of Human Induced Pluripotent Stem Cells. J Biol Chem. 2013.

Shen M, Zhao SRui, Khokhar Y, Li L, Zhou Y, Liu C, Wu JC. Protocol to generate cardiac pericytes from human induced pluripotent stem cells. STAR Protoc. 2023;4(2):102256.

Wnorowski A, Yang H, Wu JC. Progress, obstacles, and limitations in the use of stem cells in organ-on-a-chip models. Adv Drug Deliv Rev. 2018.

Kim H, Kamm RD, Vunjak-Novakovic G, Wu JC. Progress in multicellular human cardiac organoids for clinical applications. Cell Stem Cell. 2022;29(4):503-514.

Nguyen PK, Neofytou E, Rhee J-W, Wu JC. Potential Strategies to Address the Major Clinical Barriers Facing Stem Cell Regenerative Therapy for Cardiovascular Disease: A Review. JAMA Cardiol. 2016.

Huang CYing, Nicholson MW, Wang JYuan, Ting CYu, Tsai MHeng, Cheng YChe, Liu CLin, Chan DZH, Lee YChan, Hsu CChuan, et al. Population-based high-throughput toxicity screen of human iPSC-derived cardiomyocytes and neurons. Cell Rep. 2022;39(1):110643.

Shah PP, Lv W, Rhoades JH, Poleshko A, Abbey D, Caporizzo MA, Linares-Saldana R, Heffler JG, Sayed N, Thomas D, et al. Pathogenic LMNA variants disrupt cardiac lamina-chromatin interactions and de-repress alternative fate genes. Cell Stem Cell. 2021.

Smith A, Choi E, Gray K, Macadangdang J, Ahn EHyun, Clark EC, Laflamme M, Wu JC, Murry CE, Tung L, et al. NanoMEA: a tool for high-throughput, electrophysiological phenotyping of patterned excitable cells. Nano Lett. 2019.

Wu H, Yang H, Rhee J-W, Zhang JZ, Lam CKeung, Sallam K, C Y Chang A, Ma N, Lee J, Zhang H, et al. Modelling diastolic dysfunction in induced pluripotent stem cell-derived cardiomyocytes from hypertrophic cardiomyopathy patients. Eur Heart J. 2019.

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