Biblio
Autoantibodies to Harmonin and Villin Are Diagnostic Markers in Children with IPEX Syndrome. PLoS One. 2013;8(11):e78664.
. Chemically modified guide RNAs enhance CRISPR-Cas genome editing in human primary cells. Nat Biotechnol. 2015.
Congenital diarrhoeal disorders: advances in this evolving web of inherited enteropathies. Nat Rev Gastroenterol Hepatol. 2015.
. The Biology of T Regulatory Type 1 Cells and Their Therapeutic Application in Immune-Mediated Diseases. Immunity. 2018;49(6):1004-1019.
. Severe autoinflammation in four patients with C-terminal variants in CDC42 successfully treated with IL-1β inhibition. J Allergy Clin Immunol. 2019.
Treatment with Rapamycin Can Restore Regulatory T Cell Function in IPEX Patients. J Allergy Clin Immunol. 2019.
Alloantigen-specific type 1 regulatory T cells suppress through CTLA-4 and PD-1 pathways and persist long-term in patients. Sci Transl Med. 2021;13(617):eabf5264.
Epigenetic and Immunological Indicators of IPEX Disease in subjects with FOXP3 gene mutation. J Allergy Clin Immunol. 2022.
Case report: Refractory Evans syndrome in two patients with spondyloenchondrodysplasia with immune dysregulation treated successfully with JAK1/JAK2 inhibition. Front Immunol. 2023;14:1328005.
FOXP3 deficiency, from the mechanisms of the disease to curative strategies. Immunol Rev. 2023.
. FOXP3 TSDR Measurement Could Assist Variant Classification and Diagnosis of IPEX Syndrome. J Clin Immunol. 2023.
Identification of unstable regulatory and autoreactive effector T cells that are expanded in patients with mutations. Sci Transl Med. 2023;15(727):eadg6822.
IPEX Syndrome from diagnosis to cure, learning along the way. J Allergy Clin Immunol. 2023.
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