Biblio

Author Title Type [ Year(Asc)]
Filters: Author is Jaenisch, Rudolf  [Clear All Filters]
2023
Flamier A, Bisht P, Richards A, Tomasello DL, Jaenisch R. Human iPS cell-derived sensory neurons can be infected by SARS-CoV-2. iScience. 2023;26(9):107690.
Qian J, Guan X, Xie B, Xu C, Niu J, Tang X, Li CH, Colecraft HM, Jaenisch R, X Liu S. Multiplex epigenome editing of to rescue Rett syndrome neurons. Sci Transl Med. 2023;15(679):eadd4666.
Sun C, Seranova E, Cohen MA, Chipara M, Roberts J, Astuti D, Palhegyi AM, Acharjee A, Sedlackova L, Kataura T, et al. NAD depletion mediates cytotoxicity in human neurons with autophagy deficiency. Cell Rep. 2023;42(5):112372.
Richards A, Khalil A, Friesen M, Whitfield TW, Lungjangwa T, Gehrke L, Mooney D, Jaenisch R. SARS-CoV-2 infection of human pluripotent stem cell-derived vascular cells reveals smooth muscle cells as key mediators of vascular pathology during infection. bioRxiv. 2023.
2022
Friesen M, Khalil AS, M Barrasa I, Jeppesen JF, Mooney DJ, Jaenisch R. Development of a physiological insulin resistance model in human stem cell-derived adipocytes. Sci Adv. 2022;8(24):eabn7298.
Ma H, de Zwaan E, Guo YEric, Cejas P, Thiru P, van de Bunt M, Jeppesen JF, Syamala S, Dall'Agnese A, Abraham BJ, et al. The nuclear receptor THRB facilitates differentiation of human PSCs into more mature hepatocytes. Cell Stem Cell. 2022.
Ma H, de Zwaan E, Guo YEric, Cejas P, Thiru P, van de Bunt M, Jeppesen JF, Syamala S, Dall'Agnese A, Abraham BJ, et al. The nuclear receptor THRB facilitates differentiation of human PSCs into more mature hepatocytes. Cell Stem Cell. 2022;29(11):1611.
2020
Khalil AS, Jaenisch R, Mooney DJ. Engineered tissues and strategies to overcome challenges in drug development. Adv Drug Deliv Rev. 2020.
Cohen MA, Zhang S, Sengupta S, Ma H, Bell GW, Horton B, Sharma B, George RE, Spranger S, Jaenisch R. Formation of Human Neuroblastoma in Mouse-Human Neural Crest Chimeras. Cell Stem Cell. 2020.
Murai N, Mitalipova M, Jaenisch R. Functional analysis of CX3CR1 in human induced pluripotent stem (iPS) cell-derived microglia-like cells. Eur J Neurosci. 2020.
2018
Soldner F, Jaenisch R. Stem Cells, Genome Editing, and the Path to Translational Medicine. Cell. 2018;175(3):615-632.
2016
Muffat J, Li Y, Jaenisch R. CNS disease models with human pluripotent stem cells in the CRISPR age. Curr Opin Cell Biol. 2016;43:96-103.
Carroll B, Maetzel D, Maddocks ODk, Otten G, Ratcliff M, Smith GR, Dunlop EA, Passos JF, Davies OR, Jaenisch R, et al. Control of TSC2-Rheb signaling axis by arginine regulates mTORC1 activity. Elife. 2016;5.
Muffat J, Li Y, Yuan B, Mitalipova M, Omer A, Corcoran S, Bakiasi G, Tsai L-H, Aubourg P, Ransohoff RM, et al. Efficient derivation of microglia-like cells from human pluripotent stem cells. Nat Med. 2016.
Soldner F, Stelzer Y, Shivalila CS, Abraham BJ, Latourelle JC, M Barrasa I, Goldmann J, Myers RH, Young RA, Jaenisch R. Parkinson-associated risk variant in distal enhancer of α-synuclein modulates target gene expression. Nature. 2016.
2015
Cimmino L, Dawlaty MM, Ndiaye-Lobry D, Yap YSing, Bakogianni S, Yu Y, Bhattacharyya S, Shaknovich R, Geng H, Lobry C, et al. TET1 is a tumor suppressor of hematopoietic malignancy. Nat Immunol. 2015.
Stelzer Y, Shivalila CShakti, Soldner F, Markoulaki S, Jaenisch R. Tracing Dynamic Changes of DNA Methylation at Single-Cell Resolution. Cell. 2015;163(1):218-229.
2014
Buganim Y, Markoulaki S, van Wietmarschen N, Hoke H, Wu T, Ganz K, Akhtar-Zaidi B, He Y, Abraham BJ, Porubsky D, et al. The Developmental Potential of iPSCs Is Greatly Influenced by Reprogramming Factor Selection. Cell Stem Cell. 2014;15(3):295-309.
Yang H, Wang H, Jaenisch R. Generating genetically modified mice using CRISPR/Cas-mediated genome engineering. Nat Protoc. 2014;9(8):1956-1968.
Sexton AN, Regalado SG, Lai CS, Cost GJ, O'Neil CM, Urnov FD, Gregory PD, Jaenisch R, Collins K, Hockemeyer D. Genetic and molecular identification of three human TPP1 functions in telomerase action: recruitment, activation, and homeostasis set point regulation. Genes Dev. 2014.
Flierl A, Oliveira LMA, Falomir-Lockhart LJ, Mak SK, Hesley J, Soldner F, Arndt-Jovin DJ, Jaenisch R, J Langston W, Jovin TM, et al. Higher Vulnerability and Stress Sensitivity of Neuronal Precursor Cells Carrying an Alpha-Synuclein Gene Triplication. PLoS One. 2014;9(11):e112413.
Katz Y, Li F, Lambert NJ, Sokol ES, Tam WLeong, Cheng AW, Airoldi EM, Lengner CJ, Gupta PB, Yu Z, et al. Musashi proteins are post-transcriptional regulators of the epithelial-luminal cell state. Elife. 2014;3.
Theunissen TW, Powell BE, Wang H, Mitalipova M, Faddah DA, Reddy J, Fan ZPeng, Maetzel D, Ganz K, Shi L, et al. Systematic Identification of Culture Conditions for Induction and Maintenance of Naive Human Pluripotency. Cell Stem Cell. 2014.
2013
Chung CYeun, Khurana V, Auluck PK, Tardiff DF, Mazzulli JR, Soldner F, Baru V, Lou Y, Freyzon Y, Cho S, et al. Identification and Rescue of α-Synuclein Toxicity in Parkinson Patient-Derived Neurons. Science. 2013.