Biblio

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Journal Article

Burtner C, Chandrasekaran D, Santos E, Beard B, Adair J, Hamlin D, D Wilbur S, Sandmaier B, Kiem H-P. ²¹¹Astatine-conjugated monoclonal CD45 antibody-based nonmyeloablative conditioning for stem cell gene therapy. Hum Gene Ther. 2015.

Radtke S, Enstrom MR, Pande D, Duke ER, Ojeda EFabian Car, Madhu R, Owen S, Kanestrom G, Cui MLee, Perez AM, et al. Stochastic fate decisions of HSCs after transplantation: early contribution, symmetric expansion, and pool formation. Blood. 2023.

Li C, Goncalves KA, Raskó T, Pande A, Gil S, Liu Z, Izsvák Z, Papayannopoulou T, Davis JC, Kiem H-P, et al. Single-dose MGTA-145/plerixafor leads to efficient mobilization and in vivo transduction of HSCs with thalassemia correction in mice. Blood Adv. 2021;5(5):1239-1249.

Ziegler CGK, Allon SJ, Nyquist SK, Mbano IM, Miao VN, Tzouanas CN, Cao Y, Yousif AS, Bals J, Hauser BM, et al. SARS-CoV-2 Receptor ACE2 Is an Interferon-Stimulated Gene in Human Airway Epithelial Cells and Is Detected in Specific Cell Subsets across Tissues. Cell. 2020.

Petty NE, Thomas J, Radtke S, Kiem H-P. Now you see me, now you don't: New approaches to sparing nonmalignant cells from CAR T cell therapies. Med. 2023;4(11):749-751.

Haworth KG, Ironside C, Ramirez MA, Weitz S, Beard BC, Schwartz J, Adair JE, Kiem H-P. Minimal conditioning in Fanconi anemia promotes multi-lineage marrow engraftment at ten-fold lower cell doses. J Gene Med. 2018:e3050.

Peterson CW, Haworth KG, Polacino P, Huang M-L, Sykes C, Obenza WM, Repetto AC, Kashuba A, Bumgarner R, DeRosa SC, et al. Lack of viral control and development of combination antiretroviral therapy escape mutations in macaques after bone marrow transplantation. AIDS. 2015;29(13):1597-1606.

Joo JHoyoung, Wang X, Singh S, Chen C-Y, Li C, Adair JE, Kiem H-P, Rawlings DJ, Miao CH. Intraosseous delivery of platelet-targeted FVIII lentiviral vector in humanized NBSGW mice. Blood Adv. 2022.

Li C, Georgakopoulou A, Newby GA, Chen PJ, Everette KA, Paschoudi K, Vlachaki E, Gil S, Anderson AK, Koob T, et al. In vivo HSC prime editing rescues Sickle Cell Disease in a mouse model. Blood. 2023.

Cannon PM, Kiem H-P. The genome-editing decade. Mol Ther. 2021.

Radtke S, Haworth KG, Kiem H-P. The frequency of multipotent CD133(+)CD45RA(-)CD34(+) hematopoietic stem cells is not increased in fetal liver compared to adult stem cell sources. Exp Hematol. 2016.

Gori JL, Butler JM, Kunar B, Poulos MG, Ginsberg M, Nolan DJ, Norgaard ZK, Adair JE, Rafii S, Kiem H-P. Endothelial Cells Promote Expansion of Long-Term Engrafting Marrow Hematopoietic Stem and Progenitor Cells in Primates. Stem Cells Transl Med. 2016.

El-Kharrag R, Berckmueller KE, Madhu R, Cui M, Campoy G, Mack HM, Wolf CB, Perez AM, Humbert O, Kiem H-P, et al. Efficient polymer nanoparticle-mediated delivery of gene editing reagents into human hematopoietic stem and progenitor cells. Mol Ther. 2022.

Srikanthan MA, Humbert O, Haworth KG, Ironside C, Rajawat YS, Blazar BR, Palchaudhuri R, Boitano AE, Cooke MP, Scadden DT, et al. Effective Multi-lineage Engraftment in a Mouse Model of Fanconi Anemia Using Non-genotoxic Antibody-Based Conditioning. Mol Ther Methods Clin Dev. 2020;17:455-464.

Humbert O, Gisch DW, Wohlfahrt ME, Adams AB, Greenberg PD, Schmitt TM, Trobridge GD, Kiem H-P. Development of 3(rd) Generation Cocal Envelope Producer Cell Lines for Robust Lentiviral Gene Transfer into Hematopoietic Stem Cells and T Cells. Mol Ther. 2016.

Choo S, Wolf CB, Mack HM, Egan MJ, Kiem H-P, Radtke S. Choosing the right mouse model: comparison of humanized NSG and NBSGW mice for in vivo HSC gene therapy. Blood Adv. 2023.

Saha A, Hyzy S, Lamothe TLaforest, Hammond KJ, Clark NM, Lanieri L, Bhattarai PRaj, Palchaudhuri R, Gillard GO, Proctor J, et al. CD45-targeted antibody-drug-conjugate successfully conditions for allogeneic hematopoietic stem cell transplantation. Blood. 2022.

Toran PT, Wohlfahrt M, Foye J, Kiem H-P, Wojchowski DM. ASSESSMENT, AND STREAMLINED PREPARATION OF LOW CYTOTOXICITY LENTIVIRAL VECTORS FOR MOBILIZED HUMAN HEMATOPOIETIC STEM CELL TRANSDUCTION. Exp Hematol. 2020.

Samuelson C, Radtke S, Cui M, Perez A, Kiem H-P, Humbert O. AMD3100 re-dosing fails to repeatedly mobilize hematopoietic stem cells in the non-human primate and humanized mouse. Exp Hematol. 2020.

Saha A, Palchaudhuri R, Lanieri L, Hyzy S, Riddle MJ, Panthera J, Eide C, Tolar J, Panoskaltsis-Mortari A, Gorfinkel L, et al. Alloengraftment without significant toxicity or GVHD in CD45 antibody-drug conjugate conditioned Fanconi anemia mice. Blood. 2024.