Biblio
3D image analysis of the complete ventricular-subventricular zone stem cell niche reveals significant vasculature changes and progenitor deficits in males versus females with aging. Stem Cell Reports. 2021.
. 4D imaging analysis of the aging mouse neural stem cell niche reveals a dramatic loss of progenitor cell dynamism regulated by the RHO-ROCK pathway. Stem Cell Reports. 2022.
. Activation of group 2 innate lymphoid cells alleviates aging-associated cognitive decline. J Exp Med. 2020;217(4).
Assessing patient perception of risk in ocular stem cell therapies. Stem Cell Reports. 2021.
Automated Measurement of Cobblestone Morphology for Characterizing Stem Cell Derived Retinal Pigment Epithelial Cell Cultures. J Ocul Pharmacol Ther. 2016.
. Computational Image Analysis Reveals Intrinsic Multigenerational Differences between Anterior and Posterior Cerebral Cortex Neural Progenitor Cells. Stem Cell Reports. 2015.
. Defective proteostasis in induced pluripotent stem cell models of frontotemporal lobar degeneration. Transl Psychiatry. 2022;12(1):508.
. Direct differentiation of human pluripotent stem cells into vascular network along with supporting mural cells. APL Bioeng. 2023;7(3):036107.
. ELAVL4, splicing, and glutamatergic dysfunction precede neuron loss in MAPT mutation cerebral organoids. Cell. 2021.
Epigenomic and Transcriptomic Changes During Human RPE EMT in a Stem Cell Model of Epiretinal Membrane Pathogenesis and Prevention by Nicotinamide. Stem Cell Reports. 2020.
Highly Differentiated Human Fetal RPE Cultures Are Resistant to the Accumulation and Toxicity of Lipofuscin-Like Material. Invest Ophthalmol Vis Sci. 2019;60(10):3468-3479.
Human Adult Retinal Pigment Epithelial Stem Cell-Derived RPE Monolayers Exhibit Key Physiological Characteristics of Native Tissue. Invest Ophthalmol Vis Sci. 2015;56(12):7085-7099.
Human RPE Stem Cells Grown into Polarized RPE Monolayers on a Polyester Matrix Are Maintained after Grafting into Rabbit Subretinal Space. Stem Cell Reports. 2014;2(1):64-77.
Human tau mutations in cerebral organoids induce a progressive dyshomeostasis of cholesterol. Stem Cell Reports. 2022.
Identifying biomarkers of heterogeneity and transplantation efficacy in retinal pigment epithelial cells. J Exp Med. 2023;220(12).
Improved Protocol for Reproducible Human Cortical Organoids Reveals Early Alterations in Metabolism with Mutations. bioRxiv. 2023.
Interaction of Amyloid Inhibitor Proteins with Amyloid Beta Peptides: Insight from Molecular Dynamics Simulations. PLoS One. 2014;9(11):e113041.
. It Takes a Village: Constructing the Neurogenic Niche. Dev Cell. 2015;32(4):435-446.
. LEVER: software tools for segmentation, tracking and lineaging of proliferating cells. Bioinformatics. 2016.
. Mentorship in Science: Response to AlShebli et al., Nature Communications 2020. Stem Cell Reports. 2021;16(1):1-2.
. Multisensory interface for 5D stem cell image volumes. Conf Proc IEEE Eng Med Biol Soc. 2014;2014:1178-1181.
. Regenerating Eye Tissues to Preserve and Restore Vision. Cell Stem Cell. 2018;23(3):453.
. Stem cell sources and characterization in the development of cell-based products for treating retinal disease: An NEI Town Hall report. Stem Cell Res Ther. 2023;14(1):53.
Visualization and Correction of Automated Segmentation, Tracking and Lineaging from 5-D Stem Cell Image Sequences. BMC Bioinformatics. 2014;15(1):328.
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