Biblio

Author Title [ Type

] Year

Filters: Author is Leedham, Simon J [Clear All Filters]

Journal Article

Davis H, Irshad S, Bansal M, Rafferty H, Boitsova T, Bardella C, Jaeger E, Lewis A, Freeman-Mills L, Giner FC, et al. Aberrant epithelial GREM1 expression initiates colonic tumorigenesis from cells outside the stem cell niche. Nat Med. 2014.

Lannagan TRm, Jackstadt R, Leedham SJ, Sansom OJ. Advances in colon cancer research: in vitro and animal models. Curr Opin Genet Dev. 2021;66:50-56.

Flanagan DJ, Amirkhah R, Vincent DF, Gunduz N, Gentaz P, Cammareri P, McCooey AJ, McCorry AMB, Fisher NC, Davis HL, et al. Author Correction: Epithelial TGFβ engages growth-factor signalling to circumvent apoptosis and drive intestinal tumourigenesis with aggressive features. Nat Commun. 2023;14(1):522.

Koppens MAj, Davis H, Valbuena GN, Mulholland EJ, Nasreddin N, Colombe M, Antanaviciute A, Biswas S, Friedrich M, Lee L, et al. BMP pathway antagonism by Grem1 regulates epithelial cell fate in intestinal regeneration. Gastroenterology. 2021.

Vazquez EGil, Nasreddin N, Valbuena GN, Mulholland EJ, Belnoue-Davis HL, Eggington HR, Schenck RO, Wouters VM, Wirapati P, Gilroy K, et al. Dynamic and adaptive cancer stem cell population admixture in colorectal neoplasia. Cell Stem Cell. 2022;29(11):1612.

Vasquez EGil, Nasreddin N, Valbuena GN, Mulholland EJ, Belnoue-Davis HL, Eggington HR, Schenck RO, Wouters VM, Wirapati P, Gilroy K, et al. Dynamic and adaptive cancer stem cell population admixture in colorectal neoplasia. Cell Stem Cell. 2022;29(8):1213-1228.e8.

Kleeman SO, Koelzer VH, Jones HJs, Vazquez EGil, Davis H, East JE, Arnold R, Koppens MAj, Blake A, Domingo E, et al. Exploiting differential Wnt target gene expression to generate a molecular biomarker for colorectal cancer stratification. Gut. 2019.

Gooding S, Leedham SJ. Gremlin 1 - small protein, big impact: the multiorgan consequences of disrupted BMP antagonism. J Pathol. 2020.

Leedham SJ. Intestine, Heal Thyself! Regulating the Intestinal Epithelial Response to Injury. Cell Mol Gastroenterol Hepatol. 2020.

Malla SB, Byrne RM, Lafarge MW, Corry SM, Fisher NC, Tsantoulis PK, Mills ML, Ridgway RA, Lannagan TRM, Najumudeen AK, et al. Pathway level subtyping identifies a slow-cycling biological phenotype associated with poor clinical outcomes in colorectal cancer. Nat Genet. 2024.

Ali S, Bailey A, Ash S, Haghighat M, Leedham SJ, Lu X, East JE, Rittscher J, Braden B. A pilot study on automatic 3D quantification of Barrett's esophagus for risk stratification and therapy monitoring. Gastroenterology. 2021.