Stembook Sections:
Cellular and nuclear reprogramming »
  • Inducing pluripotency
  • Stem cells in animal models of regeneration
  • Small RNAs – their biogenesis, regulation and function in embryonic stem cells
Ectoderm specification and differentiation »
  • The cranial sensory nervous system: specification of sensory progenitors and placodes
  • Tooth organogenesis and regeneration
  • Melanocyte stem cells
Endoderm specification and differentiation »
  • Pancreatic stem cells
  • Specification and patterning of the respiratory system
  • Liver development
Epigenetics »
  • Epigenetic mechanisms controlling mesodermal specification
  • Imaging chromatin in embryonic stem cells
  • Epigenetic silencing during early lineage commitment
Genomics and proteomics »
  • Proteomic studies of stem cells
  • Genome-wide transcription factor localization and function in stem cells
  • The pluripotent transcriptome
Germ cell and somatic stem cell biology in reproduction »
  • Regulation of spermatogonia
  • piRNA function in germline development
  • The role of microRNAs in germline differentiation
Manufacturing »
  • Regulatory challenges for the manufacture and scale-out of autologous cell therapies
  • From production to patient: challenges and approaches for delivering cell therapies
Mesoderm specification and differentiation »
  • Epigenetic mechanisms controlling mesodermal specification
  • Mouse kidney development
  • Adult mesenchymal stem cells
Niche biology, homing, and migration »
  • Hematopoietic stem cell trafficking
  • The neural stem cell microenvironment
Renewal »
  • Aging and stem cell renewal
  • Quiescent stem cells in the niche
  • Mechanisms regulating stem cell polarity and the specification of asymmetric divisions
Stem cell immunology »
  • Immunologic targeting of the cancer stem cell
  • Immunological considerations for cell therapy using human embryonic stem cell derivatives
  • Mouse models of graft-versus-host disease
Therapeutic prospects »
  • The hematopoietic stem cell niche
  • Medical applications of epidermal stem cells
  • Mesenchymal stromal cells as a drug delivery system
Tissue engineering »
  • Combining stem cells and biomaterial scaffolds for constructing tissues and cell delivery
  • Autologous approaches to tissue engineering
  • Flow perfusion culture of mesenchymal stem cells for bone tissue engineering

Journal Stream

This week's Journalstream spans stem cell research advances in the liver and the brain, as well as describes critical insights into stem cell niche formation. In our Editor's Pick this week, Omatsu et al. describe their finding that the transcription factor Foxc1 is critical for HSC niche formation. 

Papers of the Week

News & Commentaries