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Welcome to HSCI StemCenter

The Harvard Stem Cell Institute (HSCI) unites scientists at Harvard and its affiliated hospitals with the shared goal of advancing stem cell research to treat injury and disease and the analysis of related political, legal, and ethical issues. The HSCI StemCenter publishes StemBook which provides current, peer-reviewed chapters on topics related to stem cell biology; as well as timely perspectives, interviews, and news. It serves as a resource for the stem cell research community, educators, and the interested non-specialist as well as a tool to foster discussion and build community among its readers. The Stem Center also provides links to useful biological resources such as genes, antibodies and protocols; links to key events and ability to discuss about them.

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StemBook Home

StemBook is a comprehensive, open-access collection of original, peer-reviewed chapters covering topics related to Stem Cell Biology. Read More

Cellular and nuclear reprogramming
Genomics and proteomics
Renewal
Ectoderm specification and differentiation
Germ cell and somatic stem cell biology in reproduction
Stem cell immunology
Endoderm specification and differentiation
Mesoderm specification and differentiation
Therapeutic prospects
Epigenetics
Niche biology, homing, and migration
Tissue engineering

News

Chemical found to simplify production of stem cells; Harvard team hopes technique cuts tumor risk

News, Boston Globe 11 October 2008

Researchers trying to find ways to transform human skin cells into stem cells said yesterday that they found a shortcut by adding a chemical to the cells.The chemical allowed the team at the Harvard Stem Cell Institute to use just two genes to transform skin cells into more powerful induced pluripotent stem cells, or iPS cells.To read more, click here...

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Commentaries

July 31, 2008
Random versus deterministic input into stem cell lineage choice
June 26, 2008
Stem cell maintenance factors represent potential therapeutic targets for cancer
May 30, 2008
Genomic approaches provide insights into the molecular basis of pluripotency
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