The miR-221/222 cluster regulates hematopoietic stem cell quiescence and multipotency by suppressing both Fos/AP-1/IEG pathway activation and stress-like differentiation to granulocytes.

Jani PK, Petkau G, Kawano Y, Klemm U, Guerra GMaria, Heinz GAnne, Heinrich F, Durek P, Mashreghi M-F, Melchers F. The miR-221/222 cluster regulates hematopoietic stem cell quiescence and multipotency by suppressing both Fos/AP-1/IEG pathway activation and stress-like differentiation to granulocytes. PLoS Biol. 2023;21(11):e3002015.