Ablating Lgr5-expressing prostatic stromal cells activates the ERK-mediated mechanosensory signaling and disrupts prostate tissue homeostasis.

Wei X, Zhang L, Zhang Y, Cooper C, Brewer C, Tsai C-F, Wang Y-T, Glaz M, Wessells HB, Que J, et al. Ablating Lgr5-expressing prostatic stromal cells activates the ERK-mediated mechanosensory signaling and disrupts prostate tissue homeostasis. Cell Rep. 2022;40(10):111313.