Minneapolis, MN, USA – A team of researchers at the University of Minnesota Medical School recently proved the ability to grow human-derived blood vessels in a pig—a novel approach that has the potential for providing unlimited human vessels for transplant purposes. Because these vessels were made with patient-derived skin cells, they are less likely to be rejected by the recipient, helping patients potentially avoid the need for life-long, anti-rejection drugs.
News & Commentaries
Baltimore, MD, USA – Johns Hopkins Medicine scientists say they have successfully turned back the biological hands of time, coaxing adult human cells in the laboratory to revert to a primitive state, and unlocking their potential to replace and repair damage to blood vessels in the retina caused by diabetes. The findings from this experimental study, they say, advance regenerative medicine techniques aimed at reversing the course of diabetic retinopathy and other blinding eye diseases.
Zurich, Switzerland – The University of Zurich has sent adult human stem cells to the International Space Station (ISS). Researchers from UZH Space Hub will explore the production of human tissue in weightlessness.
Storrs, CT, USA – In the journal STEM CELLS, lead investigator Dr. Ivo Kalajzic, professor of reconstructive sciences, postdoctoral fellows Dr. Sierra Root and Dr. Natalie Wee, and collaborators at Harvard, Maine Medical Research Center, and the University of Auckland present a new population of cells that reside along the vascular channels that stretch across the bone and connect the inner and outer parts of the bone.
Solna, Sweden – Researchers at Karolinska Institutet in Sweden have analysed all cell types in the human ovary and found that the hotly debated so-called egg stem cells do not exist. The results, published in Nature Communications, open the way for research on improved methods of treating involuntary childlessness.
Raleigh, NC, USA – A new study from North Carolina State University shows that lung stem cell secretions – specifically exosomes and secretomes – delivered via nebulizer, can help repair lung injuries due to multiple types of pulmonary fibrosis in mice and rats. The work could lead to more effective, less invasive treatment for human pulmonary fibrosis sufferers.
Solna, Sweden – Our skin protects us from physical injury, radiation and microbes, and at the same time produces hair and facilitates perspiration. Details of how skin cells manage such disparate tasks have so far remained elusive. Now, researchers at Karolinska Institutet in Sweden have systematically mapped skin cells and their genetic programs, creating a detailed molecular atlas of the skin in its complexity. The study is published today in the scientific journal Cell Stem Cell.
Leuven, Belgium – In the event of a bone fracture, fatty acids in our blood signal to stem cells that they have to develop into bone-forming cells. If there are no blood vessels nearby, the stem cells end up forming cartilage. The finding that specific nutrients directly influence the development of stem cells opens new avenues for stem cell research. Biomedical scientists from KU Leuven and Harvard University published these results in Nature.
London, UK – Scientists have discovered a combination of two commonly available drugs that could help the body heal spinal fractures.
Utrecht, The Netherlands – Whereas the CRISPR-Cas technology developed in 2012 cuts out a defect in a gene and replaces it with a new piece, the latest CRISPR technology works differently. The aim is to repair the error in the DNA without cutting it. This theoretically makes it a safer form of genetic editing. Scientists from Utrecht have shown for the first time that this technique can effectively and safely repair the DNA of stem cells derived from cystic fibrosis patients in the lab. The results of this study were published in the scientific journal Cell Stem Cell on the 20th of February.