Los Angeles, CA, USA – Scientists from the USC Stem Cell laboratories of Neil Segil and Justin Ichida are whispering the secrets of a simpler way to generate the sensory cells of the inner ear. Their approach uses direct reprogramming to produce sensory cells known as “hair cells,” due to their hair-like protrusions that sense sound waves. The study was published today in the journal eLife.
News & Commentaries
Los Angeles, CA, USA – A new study shows that SARS-CoV-2, the virus that causes COVID-19 (coronavirus), can infect heart cells in a lab dish, indicating it may be possible for heart cells in COVID-19 patients to be directly infected by the virus. The discovery, published today in the journal Cell Reports Medicine, was made using heart muscle cells that were produced by stem cell technology.
Skokie, IL, USA – In letters released today by the International Society for Stem Cell Research (ISSCR) to the US Food and Drug Administration (FDA) and the European Medicines Agency (EMA), the Society presses for greater enforcement to help protect patients suffering from devastating diseases including COVID-19. The effort comes as the world’s foremost stem cell and regenerative medicine researchers are meeting this week to share the field’s newest discoveries as part of ISSCR 2020 Virtual.
Mansfield, CT, USA – UConn associate professor of pharmaceutics Xiuling Lu, along with professor of chemistry Rajeswari M. Kasi, was part of a team that recently published a paper in Nature Cell Biology finding a commonly used chemotherapy drug may be repurposed as a treatment for resurgent or chemotherapy-resistant leukemia.
College Station, TX, USA – Although most broken bones can be mended with a firm cast and a generous measure of tender loving care, more complicated fractures require treatments like bone grafting. Researchers at Texas A&M University have now created superior bone grafts using primitive stem cells. They found that these cells help create very fertile scaffolds needed for the bone to regenerate at the site of repair.
London, UK – Researchers at the Francis Crick Institute have found two genes that regulate the differentiation of stem cells in the small intestine, offering valuable insight into how the body develops and maintains a healthy gut.
Chicago, IL, USA – A study published in Molecular Psychiatry shows that patient-derived adult stem cells can be used to model major depressive disorder and test how a patient may respond to medication.
Indianapolis, IN, USA – More than 3 million Americans have glaucoma, a serious eye condition causing vision loss. Using human stem cell models, researchers at Indiana University School of Medicine found they could analyze deficits within cells damaged by glaucoma, with the potential to use this information to develop new strategies to slow the disease process.
San Diego, CA, USA – Using induced pluripotent stem cells (iPSCs) and deleting a key gene, researchers at University of California San Diego School of Medicine have created natural killer cells – a type of immune cell – with measurably stronger activity against a form of leukemia, both in vivo and in vitro.