News & Commentaries

An Important Step for Regenerative Medicine: Human Blood Cells can be Directly Reprogrammed into Neural Stem Cells

DKFZ news

Heidelberg, Germany – Scientists from the German Cancer Research Center (DKFZ) and the stem cell institute HI-STEM in Heidelberg have succeeded for the first time in directly reprogramming human blood cells into a previously unknown type of neural stem cell. These induced stem cells are similar to those that occur during the early embryonic development of the central nervous system. They can be modified and multiplied indefinitely in the culture dish and can represent an important basis for the development of regenerative therapies.

Can Stem Cells Help a Diseased Heart Heal Itself?

rutgers news
New Rutgers Research Achieves Important Milestone to show how newly created cardiac muscle cells can be made to pump together

New Brunswick, NJ, USA – A team of Rutgers scientists, including Leonard Y. Lee and Shaohua Li, have taken an important step toward the goal of making diseased hearts heal themselves – a new model that would reduce the need for bypass surgery, heart transplants or artificial pumping devices.

The Immune System's Supercell – How It Matures

lund news

Lund, Sweden – NK cells, or natural killer cells, play an important role in the body's defences against cancer and various infections. Now, in a joint project, researchers at Lund University in Sweden, the University of Oxford and Karolinska Institutet in Stockholm have mapped how the different steps of the maturation process of these supercells from blood producing stem cells in the bone marrow are regulated: knowledge which is crucial for the development of new immunotherapies against cancer.

IOS Press Relaunches Stembook

STB logo
Open Access Forum for Stem Cell Research |

Amsterdam, NL – IOS Press, an international publisher providing content for scientific, technical and medical communities, is proud to announce the relaunch and revitalization of StemBook, an online open access forum and discussion platform for the stem cell research community. It features a collection of content covering a range of topics related to stem cell biology written by top researchers in the field. The site is being refreshed with new content that will be expanded and updated regularly. Enhanced functionality will also be introduced soon.

New Method For Studying ALS More Effectively


Stockholm, Sweden – The neurodegenerative disease ALS causes motor neuron death and paralysis. However, long before the cells die, they lose contact with the muscles as their axons atrophy. Researchers at Karolinska Institutet have now devised a new method that radically improves the ability to study axons and thus to better understand the pathological development of ALS.

The Source of Stem Cells Points to Two Proteins

East Lansing, MI, USA – Mammalian embryos are unlike those of any other organism as they must grow within the mother’s body. While other animal embryos grow outside the mother, their embryonic cells can get right to work accepting assignments, such as head, tail or vital organ. By contrast, mammalian embryos must first choose between forming the placenta or creating the baby.

Potential Seen to Tailor Acute Myeloid Leukemia Treatment

UW Medicine
Drug response screening of leukemia stem cells offers clues to relapse and suggests ways to improve patient-specific therapies

Seattle, WA, USA – Advances in rapid screening of leukemia cells for drug susceptibility and resistance are bringing scientists closer to patient-tailored treatment for acute myeloid leukemia (AML). Research on the drug responses of leukemia stem cells may reveal why some attempts to treat are not successful or why initially promising treatment results are not sustained.

Maintaining the Unlimited Potential of Stem Cells

salk news
Salk scientists discover new protein complex that keeps embryonic stem cells at stage of fullest potential, a key to regenerative medicine

La Jolla, CA, USA – Embryonic stem cells (ESCs) are the very definition of being full of potential, given that they can become any type of cell in the body. Once they start down any particular path toward a type of tissue, they lose their unlimited potential. Scientists have been trying to understand why and how this happens in order to create regenerative therapies that can, for example, coax a person’s own cells to replace damaged or diseased organs.