News & Commentaries

New Technique ‘Prints’ Cells to Create Diverse Biological Environments

Stembok: New Technique ‘Prints’ Cells to Create Diverse Biological Environments

Berkely, CA, USA – Like humans, cells are easily influenced by peer pressure. Take a neural stem cell in the brain: Whether this cell remains a stem cell or differentiates into a fully formed brain cell is ultimately determined by a complex set of molecular messages the cell receives from countless neighbors. Understanding these messages is key for scientists hoping to harness these stem cells to treat neurological conditions like Alzheimer’s or Parkinson’s.

A Newly Discovered Memory In Our Bones: Blood Stem Cells Boost Immunity By Keeping A Record Of Previous Infections

Stembook: A Newly Discovered Memory In Our Bones: Blood Stem Cells Boost Immunity By Keeping A Record Of Previous Infections

Dresden, Germany – A Franco-German research team led by Prof. Michael Sieweke, from the Center for Regenerative Therapies TU Dresden (CRTD) and the Center of Immunology of Marseille Luminy (CNRS, INSERM, Aix-Marseille University), today uncovered a surprising property of blood stem cells: not only do they ensure the continuous renewal of blood cells and contribute to the immune response triggered by an infection, but they can also remember previous infectious encounters to drive a more rapid and more efficient immune response in the future. These findings should have a significant impact on future vaccination strategies and pave the way for new treatments of an underperforming or over-reacting immune system. The results of this research are published in Cell Stem Cell on March 12, 2020.

University of Minnesota First to Prove New Method to Grow Human Blood Vessels

Stembook: University of Minnesota First to Prove New Method to Grow Human Blood Vessels

Minneapolis, MN, USA – A team of researchers at the University of Minnesota Medical School recently proved the ability to grow human-derived blood vessels in a pig—a novel approach that has the potential for providing unlimited human vessels for transplant purposes. Because these vessels were made with patient-derived skin cells, they are less likely to be rejected by the recipient, helping patients potentially avoid the need for life-long, anti-rejection drugs.

‘Primitive’ Stem Cells Shown to Regenerate Blood Vessels in The Eye

Stembook: ‘Primitive’ Stem Cells Shown to Regenerate Blood Vessels in The Eye

Baltimore, MD, USA – Johns Hopkins Medicine scientists say they have successfully turned back the biological hands of time, coaxing adult human cells in the laboratory to revert to a primitive state, and unlocking their potential to replace and repair damage to blood vessels in the retina caused by diabetes. The findings from this experimental study, they say, advance regenerative medicine techniques aimed at reversing the course of diabetic retinopathy and other blinding eye diseases.

‘Primitive’ Stem Cells Shown to Regenerate Blood Vessels in The Eye

Stembook: ‘Primitive’ Stem Cells Shown to Regenerate Blood Vessels in The Eye

Baltimore, MD, USA – Johns Hopkins Medicine scientists say they have successfully turned back the biological hands of time, coaxing adult human cells in the laboratory to revert to a primitive state, and unlocking their potential to replace and repair damage to blood vessels in the retina caused by diabetes. The findings from this experimental study, they say, advance regenerative medicine techniques aimed at reversing the course of diabetic retinopathy and other blinding eye diseases.

UConn Researchers Discover New Stem Cells That Can Generate New Bone

Stembook UConn Researchers Discover New Stem Cells That Can Generate New Bone

Storrs, CT, USA – In the journal STEM CELLS, lead investigator Dr. Ivo Kalajzic, professor of reconstructive sciences, postdoctoral fellows Dr. Sierra Root and Dr. Natalie Wee, and collaborators at Harvard, Maine Medical Research Center, and the University of Auckland present a new population of cells that reside along the vascular channels that stretch across the bone and connect the inner and outer parts of the bone.

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