Forum

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Jay Bradner on open source drug discovery, cancer, and targeting the epigenome

Lisa Girard

James “Jay “ Bradner, M.D. is an Assistant Professor of Medicine at Harvard Medical School, Investigator and Staff Physician at the Dana-Farber Cancer Institute, Associate Member of the Chemical Biology Program at the Broad Institute and Affiliate Faculty member of the Harvard Stem Cell Institute. His lab is focused on chemical biological approaches to studying chromatin- associated complexes with a focus on oncology. His achievements in promoting open source drug discovery have the potential to change how cancer and disease therapies are developed. Jay spoke with the StemBook editor, Lisa Girard, about his work creating chemical tools to fight cancer, his innovative approach to distributing these tools as a means of accelerating discovery, and how this just might change how pharma thinks about making medicines.

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Insights Into Post-Traumatic Stress Disorder and Mood Disorders From Adult Neurogenesis and Neural Circuitry Studies-A Conversation With Amar Sahay

Lisa Girard

Amar Sahay, Ph.D, is an Assistant Professor of Psychiatry at Harvard Medical School, Massachusetts General Hospital, Center for Regenerative Medicine, and Principal Faculty at the Harvard Stem Cell Institute. His primary research interests include how plasticity mechanisms in the adult brain affect cognition and mood and how perturbations in neural circuits may contribute to psychiatric disorders. Among other honors, Dr. Sahay has been the recipient of the Society for Neuroscience Career Development Award, the NIMH Pathway to Independence Award, and the Ellison New Scholar Award. StemBook Editor, Lisa Girard, was able to talk with Dr. Sahay recently about the exciting advances in understanding how changes in neural circuitry, specifically adult hippocampal neurogenesis, affects cognition and mood.

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Michael Young Talks to StemBook About Stem Cells, Retinal Repair, and the Eye as a Model for Stem Cell Transplantation

Lisa Girard

Michael Young, Ph.D., is Associate Scientist and Director, Ocular Regenerative Medicine Institute at Schepens Eye Research Institute, Massachusetts Eye and Ear Infirmary and Associate Professor of Ophthalmology, Harvard Medical School and Affiliated Faculty member at the Harvard Stem Cell Institute...

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The Niche, Trends in Bone Marrow Transplants and AIDS: A Conversation with David Scadden

Lisa Girard

David Scadden is the Gerald and Darlene Jordan Professor of Medicine at Harvard University. He is a hematologist/oncologist who focuses on bringing stem cell biology to patient care. He founded and directs the Center for Regenerative Medicine at the Massachusetts General Hospital and with Douglas Melton, co-founded and co-directs the Harvard Stem Cell Institute and the Harvard University Department of Stem Cell and Regenerative Biology...

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Conversation with Brock Reeve, Executive Director of the Harvard Stem Cell Institute

Lisa Girard

StemBook is launching its Forum feature with a series of interviews with a diverse group of prominent opinion leaders in stem cell research. Our first, Brock Reeve, is the Executive Director of the Harvard Stem Cell Institute (HSCI) in Cambridge Massachusetts. Along with the Faculty Directors, Brock , has overall responsibility for the operations and strategy of the HSCI whose mission is to use stem cells, both as tools and as therapies, to understand and treat injury and disease...

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