Journal Article
Xu J, Gruber PJ, Chien KR. SMAD4 is essential for human cardiac mesodermal precursor cell formation. Stem Cells. 2018.
Yan J, Zhang L, Xu J, Sultana N, Hu J, Cai X, Li J, Xu P-X, Cai C-L. Smad4 Regulates Ureteral Smooth Muscle Cell Differentiation during Mouse Embryogenesis. PLoS One. 2014;9(8):e104503.
Jia L, Lee HSeok, Wu CFu, Kundu J, Park SGyu, Kim RNam, Wang L-H, Erkin OCem, Choi J-S, Chae SWan, et al. SMAD4 suppresses AURKA-induced Metastatic Phenotypes via Degradation of AURKA in a TGF-beta-independent manner. Mol Cancer Res. 2014.
Lu Z, Han K. SMAD4 transcriptionally activates GCN5 to inhibit apoptosis and promote osteogenic differentiation in dexamethasone-induced human bone marrow mesenchymal stem cells. Steroids. 2022:108969.
Wang C, Chen Z, Wu J, Zhang Y, Hu J, Ge Q, Yang W, Xu H, Liu J, Ye Z. Small activating RNA induces myogenic differentiation of rat adipose-derived stem cells by upregulating MyoD. Int Braz J Urol. 2015;41(4):764-772.
Hamilton G, Hochmair M, Rath B, Klameth L, Zeillinger R. Small cell lung cancer: circulating tumor cells of extended stage patients express a mesenchymal-epithelial transition phenotype. Cell Adh Migr. 2016.
Jaing T-H, Chang T-Y, Chen S-H, Wen Y-C, Chuang W-Y, Yang C-P. Small cell variant of ALK-positive anaplastic large cell lymphoma with primary subcutaneous presentation: A case report. Medicine (Baltimore). 2018;97(26):e11222.
Heck AM, Wilusz CJ. Small changes, big implications: The impact of mA RNA methylation on gene expression in pluripotency and development. Biochim Biophys Acta Gene Regul Mech. 2019.
Joladarashi D, Thandavarayan RA, Babu SSuresh, Krishnamurthy P. Small Engine, Big Power: MicroRNAs as Regulators of Cardiac Diseases and Regeneration. Int J Mol Sci. 2014;15(9):15891-15911.
Li B, Zhang M, Chen S, Zhao C, Li X, Zhang X. Small extracellular vesicle-based delivery of interleukin-10 improves treatment of experimental autoimmune uveitis. Exp Eye Res. 2024:109936.
Reddy SK, Ballal AR, Shailaja S, Seetharam RN, Raghu CH, Sankhe R, Pai K, Tender T, Mathew M, Aroor A, et al. Small extracellular vesicle-loaded bevacizumab reduces the frequency of intravitreal injection required for diabetic retinopathy. Theranostics. 2023;13(7):2241-2255.
Lino MM, Rondão T, Banerjee A, Aires I, Rodrigues M, Reis T, Santinha A, Fernandes D, Serrenho D, Sobrino T, et al. Small extracellular vesicles administered directly in the brain promote neuroprotection and decreased microglia reactivity in a stroke mouse model. Nanoscale. 2023.
Li M, Sun G, Zhao J, Pu S, Lv Y, Wang Y, Li Y, Zhao X, Wang Y, Yang S, et al. Small extracellular vesicles derived from acute myeloid leukemia cells promote leukemogenesis by transferring miR-221-3p. Haematologica. 2024.
Wang J, Wei Q, Yang Y, Che M, Ma Y, Peng L, Yu H, Shi H, He G, Wu R, et al. Small extracellular vesicles derived from four dimensional-culture of mesenchymal stem cells induce alternatively activated macrophages by upregulating IGFBP2/EGFR to attenuate inflammation in the spinal cord injury of rats. Front Bioeng Biotechnol. 2023;11:1146981.
Sun J, Lin Z, Liao Z, Wu Z, Li H, Wang H. Small extracellular vesicles derived from human adipose-derived stem cells regulate energetic metabolism through the activation of YAP/TAZ pathway facilitating angiogenesis. Cell Biol Int. 2022.
Zhuang Y, Cheng M, Li M, Cui J, Huang J, Zhang C, Si J, Lin K, Yu H. Small extracellular vesicles derived from hypoxic mesenchymal stem cells promote vascularized bone regeneration through the miR-210-3p/EFNA3/PI3K pathway. Acta Biomater. 2022.
Zhang T, Wu Y, Li X, Zhang A, Liu H, Shi M, Zhang Z, Lu W, Guo Y, Tang X, et al. Small extracellular vesicles derived from tendon stem cells promote the healing of injured Achilles tendons by regulating miR-145-3p. Acta Biomater. 2023.
Suzuki H, Yokoi A, Uno K, Yoshida K, Kitagawa M, Asano-Inami E, Matsuo S, Nagao Y, Suzuki K, Nakamura K, et al. Small Extracellular Vesicles from adipose-derived stem cells suppress cell proliferation by delivering the let-7 family of microRNAs in ovarian cancer. Biochem Biophys Res Commun. 2023;680:211-219.
Zuo H, Wang Y, Yuan M, Zheng W, Tian X, Pi Y, Zhang X, Song H. Small extracellular vesicles from HO-1-modified bone marrow-derived mesenchymal stem cells attenuate ischemia-reperfusion injury after steatotic liver transplantation by suppressing ferroptosis via miR-214-3p. Cell Signal. 2023:110793.
Liang Z, Yang Z, Xie H, Rao J, Xu X, Lin Y, Wang C, Chen C. Small extracellular vesicles from hypoxia-preconditioned bone marrow mesenchymal stem cells attenuate spinal cord injury via miR-146a-5p-mediated regulation of macrophage polarization. Neural Regen Res. 2024;19(10):2259-2269.
Caller T, Rotem I, Shaihov-Teper O, Lendengolts D, Schary Y, Shai R, Glick-Saar E, Dominissini D, Motiei M, Katzir I, et al. Small Extracellular Vesicles From Infarcted and Failing Heart Accelerate Tumor Growth. Circulation. 2024.
Teo KYe Wen, Tan R, Wong KLin, Hey DHwee Weng, Hui JHoi Po, Toh WSeong. Small extracellular vesicles from mesenchymal stromal cells: the next therapeutic paradigm for musculoskeletal disorders. Cytotherapy. 2023.
Cui S, Zhang Z, Cheng C, Tang S, Zhai M, Li L, Wei F, Ding G. Small Extracellular Vesicles from Periodontal Ligament Stem Cells Primed by Lipopolysaccharide Regulate Macrophage M1 Polarization via miR-433-3p Targeting TLR2/TLR4/NF-κB. Inflammation. 2023.
Mas-Bargues C, Sanz-Ros J, Romero-García N, Huete-Acevedo J, Dromant M, Borrás C. Small extracellular vesicles from senescent stem cells trigger adaptive mechanisms in young stem cells by increasing antioxidant enzyme expression. Redox Biol. 2023;62:102668.
Wang L, Zhang H, Xiao X, Wang S, Zhao RChunhua. Small extracellular vesicles maintain homeostasis of senescent mesenchymal stem cells at least through excreting harmful lipids. Stem Cells Dev. 2023.