Aberrant epithelial GREM1 expression initiates colonic tumorigenesis from cells outside the stem cell niche. Nat Med. 2014.
BMP pathway antagonism by Grem1 regulates epithelial cell fate in intestinal regeneration. Gastroenterology. 2021.
Exploiting differential Wnt target gene expression to generate a molecular biomarker for colorectal cancer stratification. Gut. 2019.