Biblio

Author Title Type [ Year(Desc)]
Filters: Author is Spence, Jason R  [Clear All Filters]
2014
Watson CL, Mahe MM, Múnera J, Howell JC, Sundaram N, Poling HM, Schweitzer JI, Vallance JE, Mayhew CN, Sun Y, et al. An in vivo model of human small intestine using pluripotent stem cells. Nat Med. 2014.
2015
Dye BR, Hill DR, Ferguson MAh, Tsai Y-H, Nagy MS, Dyal R, Wells JM, Mayhew CN, Nattiv R, Klein OD, et al. In vitro generation of human pluripotent stem cell derived lung organoids. Elife. 2015;4.
2016
Aurora M, Spence JR. hPSC-derived lung and intestinal organoids as models of human fetal tissue. Dev Biol. 2016.
2019
Singh AP, Hung Y-H, Shanahan MT, Kanke M, Bonfini A, Dame MK, Biraud M, Peck BCE, Oyesola OO, Freund JM, et al. Enteroendocrine progenitor cell enriched miR-7 regulates intestinal epithelial proliferation in an Xiap-dependent manner. Cell Mol Gastroenterol Hepatol. 2019.
Riemondy KA, Jansing NL, Jiang P, Redente EF, Gillen AE, Fu R, Miller AJ, Spence JR, Gerber AN, Hesselberth JR, et al. Single cell RNA sequencing identifies TGFβ as a key regenerative cue following LPS-induced lung injury. JCI Insight. 2019;5.
2020
Holloway EM, Wu JH, Czerwinski M, Sweet CW, Wu A, Tsai Y-H, Huang S, Stoddard AE, Capeling MM, Glass I, et al. Differentiation of Human Intestinal Organoids with Endogenous Vascular Endothelial Cells. Dev Cell. 2020;54(4):516-528.e7.
Hor P, Punj V, Calvert BA, Castaldi A, Miller AJ, Carraro G, Stripp BR, Brody SL, Spence JR, Ichida JK, et al. Efficient Generation and Transcriptomic Profiling of Human iPSC-Derived Pulmonary Neuroendocrine Cells. iScience. 2020;23(5):101083.
Dye BR, Youngblood RL, Oakes RS, Kasputis T, Clough DW, Spence JR, Shea LD. Human lung organoids develop into adult airway-like structures directed by physico-chemical biomaterial properties. Biomaterials. 2020;234:119757.
Holloway EM, Czerwinski M, Tsai Y-H, Wu JH, Wu A, Childs CJ, Walton KD, Sweet CW, Yu Q, Glass I, et al. Mapping Development of the Human Intestinal Niche at Single-Cell Resolution. Cell Stem Cell. 2020.
Howden SE, Wilson SB, Groenewegen E, Starks L, Forbes TA, Tan KSin, Vanslambrouck JM, Holloway EM, Chen Y-H, Jain S, et al. Plasticity of distal nephron epithelia from human kidney organoids enables the induction of ureteric tip and stalk. Cell Stem Cell. 2020.
2021
Hung Y-H, Huang S, Dame MK, Yu Q, Yu QC, Zeng YA, J Camp G, Spence JR, Sethupathy P. Chromatin regulatory dynamics of early human small intestinal development using a directed differentiation model. Nucleic Acids Res. 2021.
Abuaita BH, Lawrence A-LE, Berger RP, Hill DR, Huang S, Yadagiri VK, Bons B, Fields C, Wobus CE, Spence JR, et al. Comparative transcriptional profiling of the early host response to infection by typhoidal and non-typhoidal Salmonella serovars in human intestinal organoids. PLoS Pathog. 2021;17(10):e1009987.
2022
Dye B, Decker J, Hein R, Miller A, Huang S, Spence JR, Shea LD. Human Lung Organoid Culture in Alginate With and Without Matrigel to Model Development and Disease. Tissue Eng Part A. 2022.
Hein RFC, Wu JH, Holloway EM, Frum T, Conchola AS, Tsai Y-H, Wu A, Fine AS, Miller AJ, Szenker-Ravi E, et al. R-SPONDIN2 mesenchymal cells form the bud tip progenitor niche during human lung development. Dev Cell. 2022.
Capeling MM, Huang S, Childs CJ, Wu JH, Tsai Y-H, Wu A, Garg N, Holloway EM, Sundaram N, Bouffi C, et al. Suspension culture promotes serosal mesothelial development in human intestinal organoids. Cell Rep. 2022;38(7):110379.
2023
Childs CJ, Holloway EM, Sweet CW, Tsai Y-H, Wu A, Vallie A, Eiken MK, Capeling MM, Zwick RK, Palikuqi B, et al. EPIREGULIN creates a developmental niche for spatially organized human intestinal enteroids. JCI Insight. 2023.
Bouffi C, Wikenheiser-Brokamp KA, Chaturvedi P, Sundaram N, Goddard GR, Wunderlich M, Brown NE, Staab JF, Latanich R, Zachos NC, et al. In vivo development of immune tissue in human intestinal organoids transplanted into humanized mice. Nat Biotechnol. 2023.
Hung Y-H, Capeling M, Villanueva JW, Kanke M, Shanahan MT, Huang S, Cubitt R, Rinaldi VD, Schimenti JC, Spence JR, et al. Integrative genome-scale analyses reveal post-transcriptional signatures of early human small intestinal development in a directed differentiation organoid model. BMC Genomics. 2023;24(1):641.
Frum T, Hsu PP, Hein RFC, Conchola AS, Zhang CJ, Utter OR, Anand A, Zhang Y, Clark SG, Glass I, et al. Opposing roles for TGFβ- and BMP-signaling during nascent alveolar differentiation in the developing human lung. NPJ Regen Med. 2023;8(1):48.
Chen L, Qiu X, Dupre A, Pellon-Cardenas O, Fan X, Xu X, Rout P, Walton KD, Burclaff J, Zhang R, et al. TGFB1 induces fetal reprogramming and enhances intestinal regeneration. Cell Stem Cell. 2023.
2024
Eiken MK, Childs CJ, Brastrom LK, Frum T, Plaster EM, Shachaf O, Pfeiffer S, Levine JE, Alysandratos K-D, Kotton DN, et al. Nascent matrix deposition supports alveolar organoid formation from aggregates in synthetic hydrogels. bioRxiv. 2024.