Establishment of KEIOi005-A iPSC line from urine-derived cells (UDCs) of a mild Alzheimer's disease (AD) donor with multiple risk SNPs for sporadic Alzheimer's disease (sAD). Stem Cell Res. 2022;62:102802..
Glycosaminoglycans promote osteogenesis from human induced pluripotent stem cells via neural crest induction. Biochem Biophys Res Commun. 2022;603:49-56..
Modulation by DREADD reveals the therapeutic effect of human iPSC-derived neuronal activity on functional recovery after spinal cord injury. Stem Cell Reports. 2022;17(1):127-142.
Pathogenic mutation of TDP-43 impairs RNA processing in a cell type-specific manner: implications for the pathogenesis of ALS/FTLD. eNeuro. 2022..
A set-theoretic definition of cell types with an algebraic structure on gene regulatory networks and application in annotation of RNA-seq data. Stem Cell Reports. 2022..
Developmental dysregulation of excitatory-to-inhibitory GABA-polarity switch may underlie schizophrenia pathology: A monozygotic-twin discordant case analysis in human iPS cell-derived neurons. Neurochem Int. 2021:105179.
Generation and validation of a common marmoset embryonic stem cell line ActiCre-B1 that ubiquitously expresses a tamoxifen-inducible Cre-driver. Stem Cell Res. 2021;51:102164..
Generation of a control human induced pluripotent stem cell line using the defective and persistent Sendai virus vector system. Stem Cell Res. 2021;56:102549..
Identification of hub molecules of FUS-ALS by Bayesian gene regulatory network analysis of iPSC model: iBRN. Neurobiol Dis. 2021:105364.
Integrated Collection of Stem Cell Bank Data, a Data Portal for Standardized Stem Cell Information. Stem Cell Reports. 2021.
Long-term selective stimulation of transplanted neural stem/progenitor cells for spinal cord injury improves locomotor function. Cell Rep. 2021;37(8):110019.
LOTUS overexpression via ex vivo gene transduction further promotes recovery of motor function following human iPSC-NS/PC transplantation for contusive spinal cord injury. Stem Cell Reports. 2021..
MeCP2 controls neural stem cell fate specification through miR-199a-mediated inhibition of BMP-Smad signaling. Cell Rep. 2021;35(7):109124.
A new approach to analysis of intracellular proteins and subcellular localization using cellprofiler and imageJ in combination. Methods. 2021..
Taurine rescues mitochondria-related metabolic impairments in the patient-derived induced pluripotent stem cells and epithelial-mesenchymal transition in the retinal pigment epithelium. Redox Biol. 2021;41:101921..
Transplantation of iPSC-derived corneal endothelial substitutes in a monkey corneal edema model. Stem Cell Res. 2021;55:102497..
Alpha-synuclein dynamics in induced pluripotent stem cell-derived dopaminergic neurons from a Parkinson's disease patient (PARK4) with SNCA triplication. FEBS Open Bio. 2020.
Controlling gene activation by enhancers through a drug-inducible topological insulator. Elife. 2020;9..
Generation of gene-corrected iPSCs line (KEIUi001-A) from a PARK8 patient iPSCs with familial Parkinson's disease carrying the I2020T mutation in LRRK2. Stem Cell Res. 2020;49:102073..
In vivo monitoring of remnant undifferentiated neural cells following human iPS cell-derived neural stem/progenitor cells transplantation. Stem Cells Transl Med. 2020.
Reprogramming of chimpanzee fibroblasts into a multipotent cancerous but not fully pluripotent state by transducing iPSC factors in 2i/LIF culture. Differentiation. 2020;112:67-76.
Sox21 Regulates Anapc10 Expression and Determines the Fate of Ectodermal Organ. iScience. 2020;23(7):101329.