Biblio
Accelerated transsulfuration metabolically defines a discrete subclass of amyotrophic lateral sclerosis patients. Neurobiol Dis. 2020:105025.
Activation of HERV-K(HML-2) disrupts cortical patterning and neuronal differentiation by increasing NTRK3. Cell Stem Cell. 2021.
Biphasic Activation of WNT Signaling Facilitates the Derivation of Midbrain Dopamine Neurons from hESCs for Translational Use. Cell Stem Cell. 2021;28(2):343-355.e5.
Deciphering Human Cell-Autonomous Anti-HSV-1 Immunity in the Central Nervous System. Front Immunol. 2015;6:208.
. Derivation of Diverse Hormone-Releasing Pituitary Cells from Human Pluripotent Stem Cells. Stem Cell Reports. 2016;6(6):858-872.
. Deriving human ENS lineages for cell therapy and drug discovery in Hirschsprung disease. Nature. 2016.
Developmental chromatin programs determine oncogenic competence in melanoma. Science. 2021;373(6559):eabc1048.
Directed differentiation and functional maturation of cortical interneurons from human embryonic stem cells. Cell Stem Cell. 2013;12(5):559-72.
Epigenetic control and manipulation of neuronal maturation timing. Curr Opin Genet Dev. 2024;85:102164.
. Establishing RNAge to score cellular aging and rejuvenation paradigms and identify novel age-modulating compounds. bioRxiv. 2023.
. Feeder-free Derivation of Melanocytes from Human Pluripotent Stem Cells. J Vis Exp. 2016;(109).
. Generation of human cerebral organoids with a structured outer subventricular zone. Cell Rep. 2024;43(4):114031.
A hPSC-based platform to discover gene-environment interactions that impact human β-cell and dopamine neuron survival. Nat Commun. 2018;9(1):4815.
A Human Pluripotent Stem Cell-based Platform to Study SARS-CoV-2 Tropism and Model Virus Infection in Human Cells and Organoids. Cell Stem Cell. 2020.
Lessons from inducible pluripotent stem cell models on neuronal senescence in aging and neurodegeneration. Nat Aging. 2024.
. Lipid droplets are a metabolic vulnerability in melanoma. Nat Commun. 2023;14(1):3192.
. Moving Stem Cells to the Clinic: Potential and Limitations for Brain Repair. Neuron. 2015;86(1):187-206.
. A Multiplex Human Pluripotent Stem Cell Platform Defines Molecular and Functional Subclasses of Autism-Related Genes. Cell Stem Cell. 2020;27(1):35-49.e6.
Neuron-intrinsic immunity to viruses in mice and humans. Curr Opin Immunol. 2021;72:309-317.
. Optogenetics enables functional analysis of human embryonic stem cell-derived grafts in a Parkinson's disease model. Nat Biotechnol. 2015.
. Pluripotent stem cell-based disease modeling: current hurdles and future promise. Curr Opin Cell Biol. 2015;37:102-110.
. Preclinical Efficacy and Safety of a Human Embryonic Stem Cell-Derived Midbrain Dopamine Progenitor Product, MSK-DA01. Cell Stem Cell. 2021;28(2):217-229.e7.
Programming and Reprogramming Cellular Age in the Era of Induced Pluripotency. Cell Stem Cell. 2015;16(6):591-600.
. The SATB1-MIR22-GBA axis mediates glucocerebroside accumulation inducing a cellular senescence-like phenotype in dopaminergic neurons. bioRxiv. 2023.
Targeting Homologous Recombination in Notch-Driven C. elegans Stem Cell and Human Tumors. PLoS One. 2015;10(6):e0127862.