A computational model of induced pluripotent stem-cell derived cardiomyocytes incorporating experimental variability from multiple data sources.J Physiol.(2019).
Generation of Endothelial Cells From Human Pluripotent Stem Cells.Arterioscler Thromb Vasc Biol39, 1317-1329.(2019).
Induced Pluripotent Stem Cells as a Novel Cancer Vaccine.Expert Opin Biol Ther.(2019).
Modelling diastolic dysfunction in induced pluripotent stem cell-derived cardiomyocytes from hypertrophic cardiomyopathy patients.Eur Heart J.(2019).
NanoMEA: a tool for high-throughput, electrophysiological phenotyping of patterned excitable cells.Nano Lett.(2019).
Splice-Junction-Based Mapping of Alternative Isoforms in the Human Proteome.Cell Rep29, 3751-3765.e5.(2019).
Towards Precision Medicine With Human iPSCs for Cardiac Channelopathies.Circ Res125, 653-658.(2019).
The West coast regional safety pharmacology society meeting update: Filling translational gaps in safety assessment.J Pharmacol Toxicol Methods106582.(2019).
Disease modelling and drug discovery for hypertrophic cardiomyopathy using pluripotent stem cells: how far have we come?.Eur Heart J.(2018).
Genome Editing of Induced Pluripotent Stem Cells to Decipher Cardiac Channelopathy Variant.J Am Coll Cardiol72, 62-75.(2018).
Progress, obstacles, and limitations in the use of stem cells in organ-on-a-chip models.Adv Drug Deliv Rev.(2018).
Systems-Wide Approaches in Induced Pluripotent Stem Cell Models.Annu Rev Pathol.(2018).
Human induced pluripotent stem cell-derived cardiomyocytes recapitulate the predilection of breast cancer patients to doxorubicin-induced cardiotoxicity.Nat Med.(2016).
Human-induced pluripotent stem cell approaches to model inborn and acquired metabolic heart diseases.Curr Opin Cardiol.(2016).
iPSC Model of Pulmonary Arterial Hypertension Reveals Novel Gene Expression and Patient Specificity.Am J Respir Crit Care Med.(2016).
Potential Strategies to Address the Major Clinical Barriers Facing Stem Cell Regenerative Therapy for Cardiovascular Disease: A Review.Jama Cardiol.(2016).
Extracellular Matrix can Recover the Downregulation of Adhesion Molecules after Cell Detachment and Enhance Endothelial Cell Engraftment.Sci Rep5, 10902.(2015).
Human Engineered Heart Muscles Engraft and Survive Long-Term in a Rodent Myocardial Infarction Model.Circ Res.(2015).
Hurdles to clinical translation of human induced pluripotent stem cells.J Clin Invest125, 2551-2557.(2015).
Immune Network and Response to Intramyocardial CD34+ Stem Cell Therapy in Patients with Dilated Cardiomyopathy.J Card Fail.(2015).
Induced Pluripotent Stem Cells.Jama313, 1613-1614.(2015).