Biblio

Author Title [ Type(Desc)] Year
Filters: Author is Göttgens, Berthold  [Clear All Filters]
Journal Article
Park HJung, Li J, Hannah R, Biddie S, Leal-Cervantes AI, Kirschner K, Cruz DFlores San, Sexl V, Göttgens B, Green AR. Cytokine-induced megakaryocytic differentiation is regulated by genome-wide loss of a uSTAT transcriptional program. EMBO J. 2015.
Ezer D, Moignard V, Göttgens B, Adryan B. Determining Physical Mechanisms of Gene Expression Regulation from Single Cell Gene Expression Data. PLoS Comput Biol. 2016;12(8):e1005072.
Fukushima T, Tanaka Y, Hamey FK, Chang C-H, Oki T, Asada S, Hayashi Y, Fujino T, Yonezawa T, Takeda R, et al. Discrimination of Dormant and Active Hematopoietic Stem Cells by G Marker Reveals Dormancy Regulation by Cytoplasmic Calcium. Cell Rep. 2019;29(12):4144-4158.e7.
Moignard V, Göttgens B. Dissecting stem cell differentiation using single cell expression profiling. Curr Opin Cell Biol. 2016;43:78-86.
Yang L, Rodriguez B, Mayle A, Park HJung, Lin X, Luo M, Jeong M, Curry CV, Kim S-B, Ruau D, et al. DNMT3A Loss Drives Enhancer Hypomethylation in FLT3-ITD-Associated Leukemias. Cancer Cell. 2016;29(6):922-934.
Nasrallah R, Knezevic K, Thai T, Thomas SR, Göttgens B, Lacaud G, Kouskoff V, Pimanda JE. Endoglin potentiates nitric oxide synthesis to enhance definitive hematopoiesis. Biol Open. 2015.
Wilkinson AC, Ryan DJ, Kucinski I, Wang W, Yang J, Nestorowa S, Diamanti E, Tsang JCheuk-Ho, Wang J, Campos LS, et al. Expanded Potential Stem Cell Media as a tool to study human developmental hematopoiesis in vitro. Exp Hematol. 2019.
Fitch SR, Kapeni C, Tsitsopoulou A, Wilson NK, Göttgens B, de Bruijn MF, Ottersbach K. Gata3 targets Runx1 in the embryonic haematopoietic stem cell niche. IUBMB Life. 2019.
Thambyrajah R, Mazan M, Patel R, Moignard V, Stefanska M, Marinopoulou E, Li Y, Lancrin C, Clapes T, Möröy T, et al. GFI1 proteins orchestrate the emergence of haematopoietic stem cells through recruitment of LSD1. Nat Cell Biol. 2015.
Vijayabaskar MS, Goode DK, Obier N, Lichtinger M, Emmett AML, Abidin FZ, Shar N, Hannah R, Assi SA, Lie-A-Ling M, et al. Identification of gene specific cis-regulatory elements during differentiation of mouse embryonic stem cells: An integrative approach using high-throughput datasets. PLoS Comput Biol. 2019;15(11):e1007337.
Vink CSebastiaan, Calero-Nieto FJose, Wang X, Maglitto A, Mariani SAntonella, Jawaid W, Göttgens B, Dzierzak E. Iterative Single-Cell Analyses Define the Transcriptome of the First Functional Hematopoietic Stem Cells. Cell Rep. 2020;31(6):107627.
Lawson H, Sepulveda C, van de Lagemaat LN, Durko J, Barile M, Tavosanis A, Georges E, Shmakova A, Timms P, Carter RN, et al. JMJD6 promotes self-renewal and regenerative capacity of hematopoietic stem cells. Blood Adv. 2021;5(3):889-899.
Calero-Nieto FJ, Ng FS, Wilson NK, Hannah R, Moignard V, Leal-Cervantes AI, Jimenez-Madrid I, Diamanti E, Wernisch L, Göttgens B. Key regulators control distinct transcriptional programmes in blood progenitor and mast cells. EMBO J. 2014.
Hamey FK, Göttgens B. Machine learning predicts putative haematopoietic stem cells within large single-cell transcriptomics datasets. Exp Hematol. 2019.
Belluschi S, Calderbank EF, Ciaurro V, Pijuan-Sala B, Santoro A, Mende N, Diamanti E, Sham KYen Chi, Wang X, W Y Lau W, et al. Myelo-lymphoid lineage restriction occurs in the human haematopoietic stem cell compartment before lymphoid-primed multipotent progenitors. Nat Commun. 2018;9(1):4100.
Takahashi M, Barile M, Chapple RH, Tseng Y-J, Nakada D, Busch K, Fanti A-K, Säwén P, Bryder D, Höfer T, et al. Reconciling Flux Experiments for Quantitative Modeling of Normal and Malignant Hematopoietic Stem/Progenitor Dynamics. Stem Cell Reports. 2021.
Ton M-LN, Guibentif C, Göttgens B. Single cell genomics and developmental biology: moving beyond the generation of cell type catalogues. Curr Opin Genet Dev. 2020;64:66-71.
Wilkinson AC, Goode DK, Cheng Y-H, Dickel DE, Foster S, Sendall T, Tijssen MR, Sanchez M-J, Pennacchio LA, Kirkpatrick AM, et al. Single site-specific integration targeting coupled with embryonic stem cell differentiation provides a high-throughput alternative to in vivo enhancer analyses. Biol Open. 2013;2(11):1229-38.
Moignard V, Göttgens B. Transcriptional mechanisms of cell fate decisions revealed by single cell expression profiling. Bioessays. 2014.
Sive J, Göttgens B. Transcriptional network control of normal and leukemic haematopoiesis. Exp Cell Res. 2014.
Dingler FA, Wang M, Mu A, Millington CL, Oberbeck N, Watcham S, Pontel LB, Kamimae-Lanning AN, Langevin F, Nadler C, et al. Two Aldehyde Clearance Systems Are Essential to Prevent Lethal Formaldehyde Accumulation in Mice and Humans. Mol Cell. 2020.