Author Title [ Type(Desc)] Year
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Journal Article
Sakolish C, Reese CE, Luo Y-S, Valdiviezo A, Schurdak ME, Gough A, D Taylor L, Chiu WA, Vernetti LA, Rusyn I. Analysis of Reproducibility and Robustness of a Human Microfluidic Four-Cell Liver Acinus MicroPhysiology System (LAMPS). Toxicology. 2020:152651.
Kato Y, Lim AY, Sakolish C, Valdiviezo A, Moyer H, Hewitt P, Bajaj P, Han G, Rusyn I. Analysis of reproducibility and robustness of OrganoPlate® 2-lane 96, a liver microphysiological system for studies of pharmacokinetics and toxicological assessment of drugs. Toxicol In Vitro. 2022:105464.
Marx U, Akabane T, Andersson TB, Baker E, Beilmann M, Beken S, Brendler-Schwaab S, Cirit M, David R, Dehne E-M, et al. Biology-inspired microphysiological systems to advance medicines for patient benefit and animal welfare. ALTEX. 2020.
Grimm FA, Klaren WD, Li X, Lehmler H-J, Karmakar M, Robertson LW, Chiu WA, Rusyn I. Cardiovascular Effects of Polychlorinated Biphenyls and Their Major Metabolites. Environ Health Perspect. 2020;128(7):77008.
House JS, Grimm FA, Klaren WD, Dalzell A, Kuchi S, Zhang S-D, Lenz K, Boogaard PJ, Ketelslegers HB, Gant TW, et al. Grouping of UVCB substances with new approach methodologies (NAMs) data. ALTEX. 2020.
Grimm FA, House JS, Wilson MR, Sirenko O, Iwata Y, Wright FA, Ball N, Rusyn I. Multi-dimensional in vitro bioactivity profiling for grouping of glycol ethers. Regul Toxicol Pharmacol. 2018.
Burnett SD, Blanchette AD, Grimm FA, House JS, Reif DM, Wright FA, Chiu WA, Rusyn I. Population-based toxicity screening in human induced pluripotent stem cell-derived cardiomyocytes. Toxicol Appl Pharmacol. 2019:114711.
Sakolish C, Luo Y-S, Valdiviezo A, Vernetti LA, Rusyn I, Chiu WA. Prediction of Hepatic Drug Clearance with a Human Microfluidic Four-Cell Liver Acinus MicroPhysiology System. Toxicology. 2021:152954.
Valdiviezo A, Brown GE, Michell AR, Trinconi CM, Bodke VV, Khetani SR, Luo Y-S, Chiu WA, Rusyn I. Reanalysis of Trichloroethylene and Tetrachloroethylene Metabolism to Glutathione Conjugates Using Human, Rat, and Mouse Liver Models to Improve Precision in Risk Characterization. Environ Health Perspect. 2022;130(11):117009.
Luo Y-S, Chen Z, Blanchette AD, Zhou Y-H, Wright FA, Baker ES, Chiu WA, Rusyn I. Relationships Between Constituents of Energy Drinks and Beating Parameters in Human Induced Pluripotent Cell (iPSC)-Derived Cardiomyocytes. Food Chem Toxicol. 2021:111979.
Hsieh N-H, Chen Z, Rusyn I, Chiu WA. Risk Characterization and Probabilistic Concentration-Response Modeling of Complex Environmental Mixtures Using New Approach Methodologies (NAMs) Data from Organotypic Human Stem Cell Assays. Environ Health Perspect. 2021;129(1):17004.
Blanchette AD, Grimm FA, Dalaijamts C, Hsieh N-H, Ferguson K, Luo Y-S, Rusyn I, Chiu WA. Thorough QT/QTc in a Dish: An In Vitro Human Model That Accurately Predicts Clinical Concentration-QTc Relationships. Clin Pharmacol Ther. 2018.